Browsing by Author "García Marín, Jose Juan"

Now showing items 1-6 of 6

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      Beneficial effect of ursodeoxycholic acid in patients with acyl-CoA oxidase 2 (ACOX2) deficiency-associated hypertransaminasemia 

      Alonso Peña, Marta; Espinosa Escudero, Ricardo; Herráez Aguilar, Elisa; Briz Sánchez, Oscar; Cagigal, María Luisa; González Santiago, Jesús M.; Ortega Alonso, Aida; Fernández Rodríguez, Conrado; Bujanda Fernández de Pierola, Luis ORCID; Calvo Sánchez, Marta; D'Avola, Delia; Londono, Maria Carlota; Diago, Moisés; Fernández Checa, José Carlos; García Ruiz, Carmen; Andrade, Raúl; Lammert, Frank; Prieto, Jesús; Crespo, Javier; Juanpérez, Javier; Díaz González, Álvaro; Monte, María J.; García Marín, Jose Juan (Wiley, 2022-11)
      Background and Aims: A variant (p.Arg225Trp) of peroxisomal acyl-CoA oxidase 2 (ACOX2), involved in bile acid (BA) side-chain shortening, has been associated with unexplained persistent hypertransaminasemia and ...
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      Cholangiocarcinoma 2020: the next horizon in mechanisms and management 

      Bañales Asurmendi, Jesús María ORCID; García Marín, Jose Juan; Lamarca, Angela; Rodrigues, Pedro M.; Khan, Shahid A.; Roberts, Lewis R.; Cardinale, Vincenzo; Carpino, Guido; Andersen, Jesper B.; Braconi, Chiara; Calvisi, Diego; Perugorria Montiel, María Jesús; Fabris, Luca; Boulter, Luke; Macias, Rocio I. R.; Gaudio, Eugenio; Alvaro, Domenico; Gradilone, Sergio A.; Strazzabosco, Mario; Marzioni, Marco; Coulouarn, Cédric; Fouassier, Laura; Raggi, Chiara; Invernizzi, Pietro; Mertens, Joachim C.; Moncsek, Anja; Rizvi, Sumera; Heimbach, Julie; Groot Koerkamp, Bas; Bruix, Jordi; Forner, Alejandro; Bridgewater, John; Valle, Juan W.; Gores, Gregory J. (Springer Nature, 2020-06-30)
      [EN] Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant tumours that can arise at any point of the biliary tree. Their incidence is increasing globally, currently accounting for ~15% ...
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      Patients with Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease Diagnosis 

      Lapitz Dambolenea, Ainhoa; Arbelaiz Cossio, Ander; O’Rourke, Colm J.; Lavín, José L.; Casta, Adelaida La; Ibarra, Cesar; Jimeno, Juan P.; Santos Laso, Álvaro; Izquierdo Sánchez, Laura; Krawczyk, Marcin; Perugorria Montiel, María Jesús; Jiménez Agüero, Raúl; Sanchez-Campos, Alberto; Riaño Fernández, Ioana; Gónzalez, Esperanza; Lammert, Frank; Marzioni, Marco; Rodríguez Macías, Rocío Isabel; García Marín, Jose Juan; Karlsen, Tom H.; Bujanda Fernández de Pierola, Luis ORCID; Falcón Pérez, Juan Manuel; Andersen, Jesper B.; Aransay Bañares, Ana María; Rodrigues, Pedro M.; Bañales Asurmendi, Jesús María ORCID (MDPI, 2020-03-14)
      Cholangiocarcinoma (CCA) comprises a group of heterogeneous biliary cancers with dismal prognosis. The etiologies of most CCAs are unknown, but primary sclerosing cholangitis (PSC) is a risk factor. Non-invasive diagnosis ...
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      Serum Metabolites as Diagnostic Biomarkers for Cholangiocarcinoma, Hepatocellular Carcinoma, and Primary Sclerosing Cholangitis 

      Bañales Asurmendi, Jesús María ORCID; Iñarrairaegui, Mercedes; Arbelaiz Cossio, Ander; Milkiewicz, Piotr; Muntané, Jordi; Muñoz Bellvis, Luis; La Casta, Adelaida; Gonzaz, Luis M.; Arretxe Oliden, Enara; Alonso, Cristina; Martínez Arranz, Ibon; Lapitz Dambolenea, Ainhoa; Santos Laso, Álvaro; Ávila, Matías A. ORCID; Martínez Chantar, María Luz ORCID; Bujanda Fernández de Pierola, Luis ORCID; García Marín, Jose Juan; Sangro, Bruno; Rodríguez Macías, Rocío Isabel (Wiley, 2019-08)
      Early and differential diagnosis of intrahepatic cholangiocarcinoma (iCCA) and hepatocellular carcinoma (HCC) by noninvasive methods represents a current clinical challenge. The analysis of low-molecular-weight metabolites ...
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      Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models. 

      Olaizola Rebe, Paula; Lee-Law, Pui Y.; García Fernández de Barrena, Maite; Álvarez Asiain, Laura; Cadamuro, Massimiliano ORCID; Azkargorta, Mikel; O’Rourke, Colm J.; Caballero Camino, Francisco Javier ORCID; Olaizola, Irene; Rodríguez Macías, Rocío Isabel; García Marín, Jose Juan; Serrano Maciá, Marina; Martínez Chantar, María Luz ORCID; Ávila, Matías A. ORCID; Aspichueta Celaá, Patricia; CALVISI, Diego Francesco ORCID; Evert, Matthias; Fabris, Luca; Castro, Rui ORCID; Elortza, Felix; Andersen, Jesper B.; Bujanda Fernández de Pierola, Luis ORCID; Rodrigues, Pedro M.; Perugorria, Maria Jesus ORCID; Bañales Asurmendi, Jesús María ORCID (Elsevier, 2022-07)
      [EN] BACKGROUND & AIMS: Cholangiocarcinoma (CCA) comprises a heterogeneous group of malignant tumors associated with dismal prognosis. Alterations in post-translational modifications (PTMs), including NEDDylation, result ...
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      TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation 

      Labiano Ciriza, Ibone; Agirre Lizaso, Aloña; Olaizola Rebe, Paula; Echebarria, Anne; Huici Izagirre, Maider; Olaizola, Irene; Esparza Baquer, Aitor ORCID; Sharif, Omar; Hijona Muruamendiaraz, Elizabeth; Milkiewicz, Piotr; Milkiewicz, Malgorzata; González Romero, Francisco; Aspichueta Celaá, Patricia; Monte, María J.; García Marín, Jose Juan; Vucur, Michael; Luedde, Tom; Marzioni, Marco; Mann, Derek A.; Bujanda Fernández de Pierola, Luis ORCID; Perugorria Montiel, María Jesús (Elsevier, 2022-10)
      Background & Aims: Inflammation, particularly that mediated by bacterial components translocating from the gut to the liver and binding to toll-like receptors (TLRs), is central to cholestatic liver injury. The triggering ...