BackBrowsing by Author "Abecia, Leticia"
Now showing items 1-11 of 11
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A structurally unique Fusobacterium nucleatum tannase provides detoxicant activity against gallotannins and pathogen resistance
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; Abecia Aliende, Leticia
; ; ; ; (Wiley, 2022-02)
Colorectal cancer pathogenesis and progression is associated with the presence of Fusobacterium nucleatum and the reduction of acetylated derivatives of spermidine, as well as dietary components such as tannin-rich foods. ... -
An in vitro analysis of the interaction between infliximab and granulocyte–monocyte apheresis
; Abecia Aliende, Leticia; ; ; (Elsevier, 2024-04)
Objetivo La falta de respuesta primaria y la pérdida de respuesta secundaria a los agentes antifactor de necrosis tumoral (TNF) son comunes en la enfermedad inflamatoria intestinal. El aumento de los niveles de fármaco ... -
Deciphering the impact of the mitochondrial negative regulator MCJ on host-microbiota interactions in experimental ulcerative colitis
(2021-10-29)La colitis ulcerosa (CU) es un trastorno inflamatorio crónico que afecta al intestino. Aunque la causa es desconocida, es una enfermedad multifactorial que está desencadenada por el sistema inmune, factores medioambientales, ... -
Gut microbiome and serum metabolome analyses identify molecular biomarkers and altered glutamate metabolism in fibromyalgia
; ; ; Abecia Aliende, Leticia; ; ; ; ; ; ; ; ; ; ; ; ; Bujanda Fernández de Pierola, Luis ; ; ; ; ; (Elsevier, 2019-08)
Background: Fibromyalgia is a complex, relatively unknown disease characterised by chronic, widespread musculoskeletal pain. The gut-brain axis connects the gut microbiome with the brain through the enteric nervous system ... -
Implicación de la microbiota intestinal en la respuesta a la inmunoterapia del cáncer colorrectal
(2024-06-21)[ES] La microbiota intestinal cumple importantes funciones en el organismo, pero una de las más importantes es la inmunomodulación. Se ha demostrado que la alteración de la microbiota intestinal, puede favorecer que se ... -
Mitochondrial bioenergetics boost macrophage activation, promoting liver regeneration in metabolically compromised animals
Goikoetxea Usandizaga, Naroa; ; Delgado, Teresa C.; Simón Espinosa, Jorge; Fernández Ramos, David; Barriales, Diego; Cornide, María E.; Jiménez, Mónica; Pérez Redondo, Marina; Lachiondo Ortega, Sofía; Rodríguez Agudo, Rubén; Bizkarguenaga, Maider; Diego Zalamea, Juan; Pasco, Samuel T.; Caballero Díaz, Daniel; Alfano, Benedetta; Bravo Garmendia, Miren; González Recio, Irene; Mercado Gómez, María; Gil Pitarch, Clàudia; Mabe Alvarez, Jon; Gracia Sancho, Jordi; Abecia Aliende, Leticia; Lorenzo, Oscar; Martín Sanz, Paloma; Abrescia, Nicola A.G.; Sabio, Guadalupe; Rincón, Mercedes; Anguita Castillo, Juan de Dios; Miñambres, Eduardo; Martín, César; Berenguer, Marina; Fabregat, Isabel; Casado, Marta; Peralta, Carmen; Varela Rey, Marta; Martínez Chantar, María Luz (Wiley, 2022-03)
[EN] Background and Aims Hepatic ischemia-reperfusion injury (IRI) is the leading cause of early posttransplantation organ failure as mitochondrial respiration and ATP production are affected. A shortage of donors has ... -
Mitochondrial complex I dysfunction alters the balance of soluble and membrane-bound TNF during chronic experimental colitis.
; ; ; ; ; ; ; ; Fullaondo Elordui-Zapaterieche, Asier; ; ; ; Abecia Aliende, Leticia (Nature, 2022-06)
Inflammatory bowel disease (IBD) is a complex, chronic, relapsing and heterogeneous disease induced by environmental, genomic, microbial and immunological factors. MCJ is a mitochondrial protein that regulates the metabolic ... -
Mitochondrial dysfunction promotes microbial composition that negatively impacts on ulcerative colitis development and progression
; ; ; ; ; ; ; ; ; ; ; Fullaondo Elordui-Zapaterieche, Asier; ; ; ; ; Abecia Aliende, Leticia (Nature, 2023)
Recent evidence demonstrates potential links between mitochondrial dysfunction and inflammatory bowel diseases (IBD). In addition, bidirectional interactions between the intestinal microbiota and host mitochondria may ... -
Peripheral Blood Mononuclear Cells (PBMC) Microbiome is Not Affected by Colon Microbiota in Healthy Goats
Peña Cearra, Ainize; Belanche, Alejandro; González López, Monika; Lavín, José L.; Pascual Itoiz, Miguel Ángel; Jiménez, Elisabeth; Rodríguez López, Héctor; Aransay Bañares, Ana María; Anguita Castillo, Juan de Dios; Yáñez Ruiz, David R.; Abecia Aliende, Leticia (BioMed Central, 2021-04-14)
BACKGROUND: The knowledge about blood circulating microbiome and its functional relevance in healthy individuals remains limited. An assessment of changes in the circulating microbiome was performed by sequencing peripheral ... -
Restoring cellular magnesium balance through Cyclin M4 protects against acetaminophen-induced liver damage
; ; ; ; ; ; ; ; ; ; ; Abecia Aliende, Leticia; ; ; ; ; ; ; ; Ávila, Matías A. ; ; ; ; ; ; ; ; ; ; ; ; Martínez Chantar, María Luz (Nature, 2022-11)
Drug induced liver injury (DILI) is an important cause acute liver failure. Here the authors report that serum Mg2+ serum levels decrease in patients with DILI as well as in preclinical animal models treated with acetaminophen ... -
The commensal bacterium Lactiplantibacillus plantarum imprints innate memory-like responses in mononuclear phagocytes
; Barriales, Diego; Peña Cearra, Ainize; Castelo Careaga, Janire; Palacios, Ainhoa; López, Nerea; Atondo Gondra, Estibaliz; Pascual Itoiz, Miguel Ángel; Martín Ruiz, Itziar; Sampedro, Leticia; González López, Monika; Bárcena, Laura; Martín Mateos, Teresa; Landete, José María; Prados Rosales, Rafael; Plaza Vinuesa, Laura; Muñoz, Rosario; De las Rivas, Blanca; Rodríguez, Juan Miguel; Berra Ramírez, Miren Edurne; Aransay Bañares, Ana María; Abecia Aliende, Leticia; Lavín, José L.; Rodríguez López, Héctor; Anguita Castillo, Juan de Dios (Taylor and Francis, 2021-07-05)
Gut microbiota is a constant source of antigens and stimuli to which the resident immune system has developed tolerance. However, the mechanisms by which mononuclear phagocytes, specifically monocytes/macrophages, cope ...