BackExaminar por departamento (cas.) "Medicina"
Now showing items 41-60 of 207
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Correlative super-resolution fluorescence and electron microscopy using conventional fluorescent proteins in vacuo
Peddie, Christopher J.; Domart, Marie-Charlotte; Snetkov, Xenia; O'Toole, Peter; Larijani, Banafshé
; Way, Michael; Cox, Susan; Collinson, Lucy M. (Elsevier, 2017-08)
Super-resolution light microscopy, correlative light and electron microscopy, and volume electron microscopy are revolutionising the way in which biological samples are examined and understood. Here, we combine these ... -
Código GiTEP: optimización de la atención en pacientes con tromboembolismo pulmonar grave en el ámbito de Gipuzkoa desde una intervención multidisciplinar.
(2018-06-18)La enfermedad tromboembólica venosa y más concretamente el tromboembolismo pulmonar (TEP), representa una grave amenaza para la salud, convirtiéndose en la tercera enfermedad cardiovascular por su importancia epidemiológica ... -
Current Approaches for Predicting a Lack of Response to Anti-EGFR Therapy in KRAS Wild-Type Patients
Er, Tze-Kiong; Chen, Chih-Chieh; Bujanda Fernández de Pierola, Luis; Herreros Villanueva, Marta (Hindawi Publishing, 2014)
Targeting epidermal growth factor receptor (EGFR) has been one of the most effective colorectal cancer strategies. Anti-EGFR antibodies function by binding to the extracellular domain of EGFR, preventing its activation, ... -
Dairy Product Consumption and Changes in Cognitive Performance: Two-Year Analysis of the PREDIMED-Plus Cohort
Alonso Gómez, Ángel María; (Wiley, 2022-07)
[EN] Scope Dairy consumption has been suggested to impact cognition; however, evidence is limited and inconsistent. This study aims to longitudinally assess the association between dairy consumption with cognitive changes ... -
Desarrollo y validación de una herramienta de segmentación automática del trombo para el seguimiento postoperatorio de los aneurismas de aorta abdominal tratados de forma endovascular.
(2022-03-30)El aneurisma de aorta abdominal (AAA) es una dilatación focal de la aorta que puede provocar su ruptura. El tratamiento habitual es la reparación endovascular (EVAR), que conlleva un seguimiento postoperatorio de por vida ... -
Detailed stratified GWAS analysis for severe COVID-19 in four European populations.
(Oxford University Press, 2022-12)Given the highly variable clinical phenotype of Coronavirus disease 2019 (COVID-19), a deeper analysis of the host genetic contribution to severe COVID-19 is important to improve our understanding of underlying disease ... -
Determinación del valor pronóstico y predictivo de respuesta a temozolomida de la metilación del promotor de MGMT en pacientes con gliomas de alto grado tratados en el Hospital Universitario de Donostia
(2019-06-07)El glioblastoma multiforme (GBM) es el tumor primario más frecuente del sistema nervioso central (SNC). El pronóstico de estos tumores es infausto: con el actual tratamiento estándar ¿que consiste en cirugía seguida de ... -
Determinants of Participation in a Post-Hospitalization Physical Exercise Program for Older Adults
Urquiza Abaunza, Miriam; Echeverria Garay, Iñaki ; ; Amasene Ugalde, María ; Labayen Goñi, Idoya ; ; ; ; Irazusta Astiazaran, Jon (BioMed Central, 2020-10-16)
Background: Older patients often experience a decline in physical function and cognitive status after hospitalization. Although interventions involving physical exercise are effective in improving functional performance, ... -
Development and external validation of a faecal immunochemical test-based prediction model for colorectal cancer detection in symptomatic patients
Cubiella, Joaquín; Vega, Pablo; Salve, María; Díaz-Ondina, Marta; Alves, Maria Teresa; Quintero, Enrique; Álvarez-Sánchez, Victoria; Fernández-Bañares, Fernando; Boadas, Jaume; Campo, Rafel; Bujanda Fernández de Pierola, Luis; Clofent, Joan; Ferrandez, Ángel; Torrealba, Leyanira; Piñol, Virginia; Rodríguez-Alcalde, Daniel; Hernández, Vicent; Fernández-Seara, Javier; COLONPREDICT study investigators (Biomed Central, 2016-08-31)
Background: Risk prediction models for colorectal cancer (CRC) detection in symptomatic patients based on available biomarkers may improve CRC diagnosis. Our aim was to develop, compare with the NICE referral criteria and ... -
Diastolic Dysfunction and Exercise Capacity in Patients with Metabolic Syndrome and Overweight/Obesity
Alonso Gómez, Ángel María; Tojal Sierra, Lucas; Fortuny Frau, Elena; Goicolea Güemez, Leire; Aboitiz Uribarri, Ane; Portillo Baquedano, María Puy ; Toledo, Estefanía; Schröder, Helmut; Salas Salvadó, Jordi; Arós Borau, Luis Fernando (Elsevier, 2019-03)
Background: Left ventricle diastolic dysfunction (LVDD) is a common finding in high risk individuals, its presence being associated with reduced exercise capacity (EC). We assessed the prevalence of LVDD, applying the 2016 ... -
Dietary diversity and depression: cross-sectional and longitudinal analyses in Spanish adult population with metabolic syndrome. Findings from PREDIMED-Plus trial
; ; ; ; ; ; ; ; Alonso Gómez, Ángel María; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; (Cambridge University Press, 2023-03)
Objective: To examine the cross-sectional and longitudinal (2-year follow-up) associations between dietary diversity (DD) and depressive symptoms. Design: An energy-adjusted dietary diversity score (DDS) was assessed ... -
Dietary Diversity and Nutritional Adequacy among an Older Spanish Population with Metabolic Syndrome in the PREDIMED-Pl us Study:A Cross-Sectional Analysis
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; Alonso Gómez, Ángel María; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; (MDPI, 2019-04-26)
Dietary guidelines emphasize the importance of a varied diet to provide an adequate nutrient intake. However, an older age is often associated with consumption of monotonous diets that can be nutritionally inadequate, ... -
Dietary Intake in Population with Metabolic Syndrome: Is the Prevalence of Inadequate Intake Influenced by Geographical Area? Cross-Sectional Analysis from PREDIMED-Plus Study
; ; ; ; ; ; ; ; ; ; ; ; ; Alonso Gómez, Ángel María; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; (MDPI, 2018-11-04)
Inadequate diet influences chronic diseases such as cardiovascular disease (CVD), the leading cause of death in Spain. CVD figures vary from one geographical region to another; this could be associated with different food ... -
Differential activity of GSK-3 isoforms regulates NF-kappa B and TRAIL- or TNF alpha induced apoptosis in pancreatic cancer cells
Zhang, J.S.; Herreros Villanueva, Marta; Koenig, A.; Deng, Z.; M De Narvajas, A. A.; Gómez, T. S.; Meng, X.; Bujanda Fernández de Pierola, Luis; Ellenrieder, V.; Li, X. K.; Kaufmann, S. H.; Billadeau, D. D. (Nature Publishing Group, 2014-03)
While TRAIL is a promising anticancer agent due to its ability to selectively induce apoptosis in neoplastic cells, many tumors, including pancreatic ductal adenocarcinoma (PDA), display intrinsic resistance, highlighting ... -
Differentially Deregulated MicroRNAs as Novel Biomarkers for Neoplastic Progression in Ulcerative Colitis.
; ; ; ; ; ; ; Bujanda Fernández de Pierola, Luis; ; ; ; ; ; ; ; ; ; (Wolters Kluwer, 2022)
INTRODUCTION: Colorectal cancer (CRC) is a potentially life-threatening complication of long-standing ulcerative colitis (UC). MicroRNAs (miRNA) are epigenetic regulators that have been involved in the development of ... -
Discoidin Domain Receptor 2 Expression as Worse Prognostic Marker in Invasive Breast Cancer
Romayor Arredondo, Irene; Luque García Vaquero, Marina; Márquez Clavijo, Joana ; Arteta Ruiz, Beatriz ; Barceló Galíndez, José Ramón; Benedicto García, Aitor (Wiley, 2022)
[EN] Discoidin domain receptor 2 (DDR2) is arising as a promising therapeutic target in breast carcinoma (BC). The ability of DDR2 to bind to collagen promotes protumoral responses in cancer cells that influence the tumor ... -
Documento de consenso para el manejo de la esquistosomiasis en atención primaria
(Elsevier, 2022-08)Human schistosomiasis is the parasitic disease with the highest morbidity and morta-lity worldwide after malaria. It is endemic in more than 78 tropical and subtropical countries, especially in sub-Saharan Africa, and it ... -
Dysautonomia in COVID-19 Patients: A Narrative Review on Clinical Course, Diagnostic and Therapeutic Strategies
(Frontiers Media, 2022-05)IntroductionOn March 11, 2020, the World Health Organization sounded the COVID-19 pandemic alarm. While efforts in the first few months focused on reducing the mortality of infected patients, there is increasing data on ... -
Effect of an Intensive Lifestyle Intervention on Circulating Biomarkers of Atrial Fibrillation-Related Pathways among Adults with Metabolic Syndrome: Results from a Randomized Trial
; ; ; Alonso Gómez, Ángel María; ; ; ; ; ; ; ; (MDPI, 2024-04-07)
Background: Lifestyles influence atrial fibrillation (AF) risk. Determining the effect of lifestyle interventions on blood concentrations of biomarkers of AF-related pathways could help understand AF pathophysiology and ... -
Effectiveness of a Structured Group Intervention Based on Pain Neuroscience Education for Patients with Fibromyalgia in Primary Care: a Multicentre Randomized Open-Label Controlled Trial
; Muñoa Capron Manieux, María; ; ; ; ; ; ; ; ; Zorrilla Artero, Ana Isabel ; Larrinaga Embeita, Gorka ; ; (Wiley, 2021-05)
Background There has been increased interest in pain neuroscience education (PNE) as a therapeutic approach for the management of fibromyalgia (FM). Methods A multicentre randomized, open-label, controlled trial was ...