Now showing items 21-25 of 25

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      Prioritization of candidate cancer genes-an aid to oncogenomic studies 

      Furney, Simon J.; Calvo Molinos, Borja ORCID; Larrañaga, Pedro; Lozano Alonso, José Antonio; López Bigas, Nuria (Oxford University Press, 2008-10)
      The development of techniques for oncogenomic analyses such as array comparative genomic hybridization, messenger RNA expression arrays and mutational screens have come to the fore in modern cancer research. Studies utilizing ...
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      Radiotherapy plus nimotuzumab or placebo in the treatment of high grade glioma patients: results from a randomized, double blind trial 

      Solomón, María Teresa; Selva, Julio César; Figueredo, Javier; Vaquer, José; Toledo, Carolina; Quintanal, Nelson; Salva, Silvia; Domínguez, Rafael; Alert, José; Marinello, Jorge Juan; Catalá, Mauricio; González Griego, Martha; Martell, Juan Antonio; Lorenzo Luaces, Patricia; Ballesteros Rodríguez, Francisco Javier ORCID; De Castro, Niurys; Bach, Ferdinand; Crombet, Tania (BioMed Central, 2013-06-19)
      Background The prognosis of patients bearing high grade glioma remains dismal. Epidermal Growth Factor Receptor (EGFR) is well validated as a primary contributor of glioma initiation and progression. Nimotuzumab is a ...
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      Snail heterogeneity in clear cell renal cell carcinoma 

      Zaldumbide Dueñas, Laura; Erramuzpe Aliaga, Asier; Guarch, Rosa; Pulido Murillo, Rafael; Cortés Díaz, Jesús María (Biomed Central, 2016-03-08)
      Background: Intratumor heterogeneity may be responsible of the unpredictable aggressive clinical behavior that some clear cell renal cell carcinomas display. This clinical uncertainty may be caused by insufficient sampling, ...
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      Structural Basis for Feed-Forward Transcriptional Regulation of Membrane Lipid Homeostasis in Staphylococcus aureus 

      Albanesi, Daniela; Reh, Georgina; Guerín, Marcelo Eduardo; Schaeffer, Francis; Debarbouille, Michel; Buschiazzo, Alejandro; Schujman, Gustavo E.; De Mendoza, Diego; Alzari, Pedro M. (Public Library of Science, 2013-01-03)
      The biosynthesis of membrane lipids is an essential pathway for virtually all bacteria. Despite its potential importance for the development of novel antibiotics, little is known about the underlying signaling mechanisms ...
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      The Carpathian range represents a weak genetic barrier in South-East Europe 

      Hervella Afonso, Montserrat ORCID; Izagirre Arribalzaga, Neskuts ORCID; Alonso Alegre, Santos ORCID; Ioana, Mihai; Netea, Mihai G.; De la Rúa Vaca, Concepción ORCID (Biomed Central, 2014-05-15)
      Background: In the present study we have assessed whether the Carpathian Mountains represent a genetic barrier in East Europe. Therefore, we have analyzed the mtDNA of 128 native individuals of Romania: 62 of them from the ...