Browsing by Author "Abad García, Beatriz"
Now showing items 1-7 of 7
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A UHPLC-Mass Spectrometry View of Human Melanocytic Cells Uncovers Potential Lipid Biomarkers of Melanoma
Pérez Valle, Arantza; Abad García, Beatriz; Fresnedo Aranguren, María Olatz; Barreda Gómez, Gabriel; Aspichueta Celaá, Patricia; Asumendi Mallea, Aintzane ; Astigarraga Arribas, Egoitz; Fernández González, José Andrés ; Boyano López, María Dolores ; Ochoa Olascoaga, Begoña (MDPI, 2021-10-08)Melanoma is the deadliest form of skin cancer due to its ability to colonize distant sites and initiate metastasis. Although these processes largely depend on the lipid-based cell membrane scaffold, our understanding of ... -
Comparative study of the lipid profile of tears and plasma enriched in growth factors.
Acera Osa, Arantxa; Abad García, Beatriz; Pereiro Díez, Xandra ; Rodríguez, Francisco David; Ruzafa Andrés, Noelia ; Durán de la Colina, Juan Antonio; Vecino Cordero, Elena (Elsevier, 2022-06)[EN] The Tear Film Lipid Layer (TFLL) acts primarily as an interface between the aqueous layer and air. Tear film lipid is composed of a thin layer of polar lipids that interact with the secretory layer of the underlying ... -
Erythrocyte Membrane Nanomechanical Rigidity Is Decreased in Obese Patients
Sot, Jesús; García Arribas, Aritz ; Abad García, Beatriz; Arranz, Sara; Portune, Kevin; Andrade, Fernando; Martín Nieto, Alicia; Velasco, Olaia; Arana, Eunate; Tueros, Itziar; Ferreri, Carla; Gaztambide Sáenz, María Sonia; Goñi Urcelay, Félix María ; Castaño González, Luis Antonio ; Alonso Izquierdo, Alicia (MDPI, 2022-02-08)This work intends to describe the physical properties of red blood cell (RBC) membranes in obese adults. The hypothesis driving this research is that obesity, in addition to increasing the amount of body fat, will also ... -
Lipidomic data uncover extensive heterogeneity in phosphatidylcholine structural variants in HepG2 cells
Chico Carmona, Yolanda; Abad García, Beatriz; Ochoa Olascoaga, Begoña; Martínez San Pelayo, María José (Elsevier, 2019-10-04)The data contain information related to the research article entitled "Profiling of promoter occupancy by the SND1 transcriptional coactivator identifies downstream glycerolipid metabolic genes involved in TNF alpha response ... -
Tri-Reagent Homogenate Is a Suitable Starting Material for UHPLC-MS Lipidomic Analysis
Background: Transcriptomic and lipidomic dual analyses usually initiate with independent extractive procedures. That entails a difficulty in aligning results from both omics platforms, especially in the case of highly ... -
Untargeted Metabolomic Liquid Chromatography High-Resolution Mass Spectrometry Fingerprinting of Apple Cultivars for the Identification of Biomarkers Related to Resistance to Rosy Apple Aphid
Alonso Rojas, Rosa María ; Berrueta Simal, Luis Angel; Abad García, Beatriz; Sasía-Arriba, Andrea; Asensio Regalado, Carlos ; Dapena, Enrique; Gallo Hermosa, Blanca (American Chemical Society, 2022-06-10)Liquid chromatography high-resolution mass spectrometry fingerprinting together with pattern recognition techniques was used to determine the metabolites involved in the susceptibility of apple cultivars to rosy apple aphid ... -
Using the Synergy between HPLC-MS and MALDI-MS Imaging to Explore the Lipidomics of Clear Cell Renal Cell Carcinoma
Martín Saiz, Lucía; Abad García, Beatriz; Solano Iturri, Jon Danel; Mosteiro González, Lorena; Martín Allende, Javier; Rueda Estévez, Yuri ; Pérez Fernández, Amparo; Unda Urzaiz, Jesús Miguel; Coterón Ochoa, Pedro; Goya, Aintzane; Saiz, Alberto; Martínez, Jennifer; Ochoa Olascoaga, Begoña; Fresnedo Aranguren, María Olatz; Larrinaga Embeita, Gorka ; Fernández González, José Andrés (American Chemical Society, 2023-01)Lipid imaging mass spectrometry (LIMS) has been tested in several pathological contexts, demonstrating its ability to segregate and isolate lipid signatures in complex tissues, thanks to the technique’s spatial resolution. ...