Browsing by Author "Baguley, Tyler D."
Now showing items 1-2 of 2
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Down-regulation of BDNF in cell and animal models increases striatal-enriched protein tyrosine phosphatase 61 (STEP61) levels
Xu, Jian; Kurup, Pradeep; Azkona Mendoza, Garikoitz; Baguley, Tyler D.; Saavedra, Ana; Nairn, Angus C.; Ellman, Jonathan A.; Pérez Navarro, Esther; Lombroso, Paul J. (Wiley, 2015-08-28)
Brain-derived neurotrophic factor (BDNF) regulates synaptic strengthening and memory consolidation, and altered BDNF expression is implicated in a number of neuropsychiatric and neurodegenerative disorders. BDNF potentiates ... -
Striatal-enriched protein tyrosine phosphatase modulates nociception: evidence from genetic deletion and pharmacological inhibition
Azkona, Garikoitz; Saavedra, Ana; Aira Muga, Zigor; Aluja, David; Xifró, Xavier; Baguley, Tyler D.; Alberch, Jordi; Ellman, Jonathan A.; Lombroso, Paul J.; Azkue Barrenetxea, Jon Jatsu; Pérez Navarro, Esther (International Association for the Study of Pain, 2016-02)
The information from nociceptors is processed in the dorsal horn of the spinal cord by complex circuits involving excitatory and inhibitory interneurons. It is well documented that GluN2B and ERK1/2 phosphorylation contributes ...