BackBrowsing by Author "López Almaraz, Ricardo"
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Clinical management of the acute complications of sickle cell anemia: 11 years of experience in a tertiary hospital
(Elsevier, 2022-07)Sickle cell disease is an emerging anemia in Europe leading to high morbidity with severe acute complications requiring hospital admission and chronic consequences. The management of these patients is complex and needs ... -
Dual-Specificity Phosphatases in Neuroblastoma Cell Growth and Differentiation
Nunes Xavier, Caroline E.; Zaldumbide Dueñas, Laura; Aurtenetxe, Olaia; López Almaraz, Ricardo; López Fernández de Villaverde, José Ignacio
; Pulido Murillo, Rafael (MDPI, 2019-03-01)
Dual-specificity phosphatases (DUSPs) are important regulators of neuronal cell growth and differentiation by targeting proteins essential to neuronal survival in signaling pathways, among which the MAP kinases (MAPKs) ... -
Identification of germline cancer predisposition variants in pediatric sarcoma patients from somatic tumor testing
(Nature, 2023-02)Genetic predisposition is an important risk factor for cancer in children and adolescents but detailed associations of individual genetic mutations to childhood cancer are still under intense investigation. Among pediatric ... -
Protein tyrosine phosphatase modulates cell growth and associates with poor outcome in human neuroblastoma
Nunes Xavier, Caroline E.; Aurtenetxe, Olaia; Zaldumbide Dueñas, Laura; López Almaraz, Ricardo; Erramuzpe Aliaga, Asier; Cortés Díaz, Jesús María; López Fernández de Villaverde, José Ignacio; Pulido Murillo, Rafael (BMC, 2019-12-14)
Background Protein tyrosine phosphatases (PTPs) regulate neuronal differentiation and survival, but their expression patterns and functions in human neuroblastoma (NB) are scarcely known. Here, we have investigated the ... -
Tumores muy raros en niños y adolescentes en España: ¿de donde venimos? ¿donde estamos? ¿hacia donde vamos?
(2023-09-27)A medida que lean y/o escuchen este trabajo, comprenderán por qué comienza con el epígrafe ¿Si trabajas en cánceres frecuentes, ¡haz ensayos aleatorios! Si trabajas en cánceres raros, ¡ENCUENTRA AMIGOS!¿, y que se ha ...