Browsing by Author "Marchetti, Piero"

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      A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells 

      González Moro, Itziar ORCID; Rojas Márquez, Henar; Sebastián de la Cruz, Maialen ORCID; Mentxaka Salgado, Jon; Olazagoitia Garmendia, Ane; Mendoza Gómez, Luis Manuel; Lluch, Aina; Fantuzzi, Federica; Lambert, Carmen; Ares Blanco, Jessica; Marselli, Lorella; Marchetti, Piero; Cnop, Miriam; Delgado, Elías; Fernández Real, José Manuel; Ortega, Francisco José; Castellanos Rubio, Ainara; Santín Gómez, Izortze (Frontiers Media, 2023-02)
      IntroductionMost of the disease-associated single nucleotide polymorphisms (SNPs) lie in non- coding regions of the human genome. Many of these variants have been predicted to impact the expression and function of long ...
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      The T1D-associated lncRNA Lnc13 modulates human pancreatic β cell inflammation by allele-specific stabilization of STAT1 mRNA 

      González Moro, Itziar ORCID; Olazagoitia Garmendia, Ane; Colli, Maikel L.; Cobo Vuilleumier, Nadia; Postler, Thomas S.; Marselli, Lorella; Marchetti, Piero; Ghosh, Sankar; Gauthier, Benoit R.; Eizirik, Decio L.; Castellanos Rubio, Ainara; Santín Gómez, Izortze (National Academy of Sciences, 2020-03-05)
      The vast majority of type 1 diabetes (T1D) genetic association signals lie in non-coding regions of the human genome. Many have been predicted to affect the expression and secondary structure of long non-coding RNAs ...