Browsing by Author "Mestre, Daniela"

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      Atorvastatin Provides a New Lipidome Improving Early Regeneration After Partial Hepatectomy in Osteopontin Deficient Mice 

      Núñez García, Maitane; Gómez Santos, Beatriz; Saenz de Urturi Indart, Diego; Mestre, Daniela; González Romero, Francisco; Buqué García, Xabier ORCID; Gutiérrez de Juan, Virginia; Martínez Chantar, María Luz ORCID; Syn, Wing-Kin; Fresnedo Aranguren, María Olatz; Aspichueta Celaá, Patricia (Nature Publishing Group, 2018-10-02)
      Osteopontin (OPN), a multifunctional cytokine that controls liver glycerolipid metabolism, is involved in activation and proliferation of several liver cell types during regeneration, a condition of high metabolic demands. ...
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      Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation 

      Barbier Torres, Lucía; Fortner, Karen A.; Iruzubieta, Paula; Delgado, Teresa C.; Giddings, Emily; Chen, Youdinghuan; Champagne, Devin; Fernández Ramos, David; Mestre, Daniela; Gómez Santos, Beatriz; Varela Rey, Marta; Gutiérrez de Juan, Virginia; Fernández Tussy, Pablo; Zubiete Franco, Imanol; García Monzón, Carmelo; González Rodríguez, Águeda; Oza, Dhaval; Valença Pereira, Felipe; Fang, Qian; Crespo, Javier; Aspichueta Celaá, Patricia; Tremblay, Frederic; Christensen, Brock C.; Anguita Castillo, Juan de Dios; Martínez Chantar, María Luz ORCID; Rincón, Mercedes (Nature, 2020-07-03)
      Nonalcoholic fatty liver disease (NAFLD) is considered the next major health epidemic with an estimated 25% worldwide prevalence. No drugs have yet been approved and NAFLD remains a major unmet need. Here, we identify MCJ ...