Browsing by Author "Mihigo, Helene B."

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      Di-aryl guanidinium derivatives: Towards improved α2-Adrenergic affinity and antagonist activity 

      McMullan, Michela; Kelly, Brendan; Mihigo, Helene B.; Keogh, Aaron P.; Rodríguez, Fernando; Brocos Mosquera, Iria; García Bea, Aintzane; Miranda Azpiazu, Patricia; Callado Hernando, Luis Felipe ORCID; Rozas, Isabel (Elsevier, 2021-01-01)
      Compounds with excellent receptor engagement displaying alpha(2)-AR antagonist activity are useful not only for therapeutic purposes (e.g. antidepressants), but also to help in the crystallization of this particular GPCR. ...