Browsing by Author "Nadjar, Agnes"

Now showing items 1-2 of 2

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      Essential Omega-3 Fatty Acids Tune Microglial Phagocytosis of Synaptic Elements in the Mouse Developing Brain 

      Madore, C.; Leyrolle, Quentin; Morel, L.; Rossitto, M.; Greenhalgh, A. D.; Delpech, J. C.; Martinat, M.; Bosch-Bouju, Clémentine; Bourel, J.; Rani, B.; Lacabanne, C.; Thomazeau, Aurore; Hopperton, K. E.; Beccari Galeano, Marlene Soledad; Sere, A.; Aubert, A.; De Smedt-Peyrusse, Véronique; Lecours, Cynthia; Bisht, K.; Fourgeaud, L.; Gregoire, S.; Bretillon, L.; Acar, N.; Grant, N. J.; Badaut, J.; Gressens, P.; Sierra Saavedra, Amanda; Butovsky, O.; Tremblay, Marie-Ève; Bazinet, R. P.; Joffre, C.; Nadjar, Agnes; Layé, Sophie (Nature, 2020-11-30)
      Omega-3 fatty acids (n-3 PUFAs) are essential for the functional maturation of the brain. Westernization of dietary habits in both developed and developing countries is accompanied by a progressive reduction in dietary ...
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      Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling 

      Abiega Etxabe, Oihane; Beccari Galeano, Marlene Soledad; Diaz-Aparicio, Irune; Nadjar, Agnes; Layé, Sophie; Leyrolle, Quentin; Gómez-Nicola, Diego; Domercq García, María ORCID; Pérez-Samartín, Alberto; Sánchez-Zafra, Víctor; Paris Guerrero, Ignacio; Valero Gómez-Lobo, Jorge; Savage, Julie C.; Hui, Chin-Wai; Tremblay, Marie-Ève; Deudero, Juan J. P.; Brewster, Amy L.; Anderson, Anne E.; Zaldumbide Dueñas, Laura; Galbarriatu, Lara; Marinas, Ainhoa; Vivanco Ruiz, María del Mar; Matute Almau, Carlos José; Maletic-Savatic, Mirjana; Encinas Pérez, Juan Manuel; Sierra Saavedra, Amanda (2016)
      Phagocytosis by microglia is tightly coupled to apoptosis, swiftly removing apoptotic cells and actively maintaining tissue homeostasis, but the neuronal hyperactivity associated with epilepsy disrupts the ATP gradients ...