Browsing by Author "Petersen, Kamilla Vandsø"

Now showing items 1-2 of 2

    • Thumbnail

      Gel-Free Tools for Quick and Simple Screening of Anti-Topoisomerase 1 Compounds 

      Keller, Josephine Geertsen; Petersen, Kamilla Vandsø; Mizielinski, Karol; Thiesen, Celine; Bjergbæk, Lotte; Reguera, Rosa M.; Pérez-Pertejo, Yolanda; Balaña-Fouce, Rafael; Trejo, Ángela; Masdeu Margalef, Carme; Alonso Pérez, Concepción Estibaliz ORCID; Knudsen, Birgitta R.; Tesauro, Cinzia (MDPI, 2023-04-27)
      With the increasing need for effective compounds against cancer or pathogen-borne diseases, the development of new tools to investigate the enzymatic activity of biomarkers is necessary. Among these biomarkers are DNA ...
    • Thumbnail

      Simple and Fast DNA Based Sensor System for Screening of Small-Molecule Compounds Targeting Eukaryotic Topoisomerase 1 

      Petersen, Kamilla Vandsø; Selas Lanseros, Asier; Hymøller, Kirstine Mejlstrup; Mizielinski, Karol; Thorsager, Maria; Stougaard, Magnus; Alonso Pérez, Concepción Estibaliz ORCID; Palacios Gambra, Francisco Javier ORCID; Pérez-Pertejo, Yolanda; Reguera, Rosa M.; Balaña-Fouce, Rafael; Knudsen, Birgitta Ruth; Tesauro, Cinzia (MDPI, 2021-08-13)
      Background: Eukaryotic topoisomerase 1 is a potential target of anti-parasitic and anti-cancer drugs. Parasites require topoisomerase 1 activity for survival and, consequently, compounds that inhibit topoisomerase 1 activity ...