Browsing by Author "Qi, Xin"

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      Allosteric control of dynamin-related protein 1 through a disordered C-terminal Short Linear Motif 

      Pérez Jover, María Isabel; Rochon, Kristy; Hu, Di; Mahajan, Mukesh; Mohan, Pooja Madan; Santos Pérez, Isaac; Ormaetxea Gisasola, Julene; Martínez Gálvez, Juan Manuel; Agirre, Jon; Qi, Xin; Mears, Jason A.; Shnyrova Zhadan, Anna ORCID; Ramachandran, Rajesh (Nature, 2024-01)
      The mechanochemical GTPase dynamin-related protein 1 (Drp1) catalyzes mitochondrial and peroxisomal fission, but the regulatory mechanisms remain ambiguous. Here we find that a conserved, intrinsically disordered, six-residue ...