Browsing by Author "Raaijmakers, Jonne A."
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Chromosomes trapped in micronuclei are liable to segregation errors
Soto, Mar; García Santisteban, Iraia ; Krenning, Lenno; Medema, René H.; Raaijmakers, Jonne A. (Company Biologist LTD, 2018-07-09)DNA in micronuclei is likely to get damaged. When shattered DNA from micronuclei gets reincorporated into the primary nucleus, aberrant rearrangements can take place, a phenomenon referred to as chromothripsis. Here, we ...