Examinar por departamento (cas.) "Bioquímica y Biología Molecular"

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      A functional variant that affects exon-skipping and protein expression of SP140 as genetic mechanism predisposing to multiple sclerosis 

      Matesanz, Fuencisla; Potenciano, Victor; Fedetz, María; Ramos-Mozo, Priscilla; Abad-Grau, María del Mar; Karaky, Mohamed; Barrionuevo, Cristina; Izquierdo, Guillermo; Ruiz-Peña, Juan Luis; García-Sánchez, María Isabel; Lucas, Miguel; Fernández, Óscar; Leyva, Laura; Otaegui, David; Muñoz-Culla, Maider; Olascoaga, Javier; Vandenbroeck, Koen; Alloza Moral, Iraide; Astobiza Pérez, Janire; Rodríguez-Antigüedad Zarranz, Alfredo; Villar, Luisa M.; Alvarez-Cermeño, José Carlos; Malhotra, Sunny; Comabella, Manuel; Montalbán, Xavier; Saiz, Albert; Blanco, Yolanda; Arroyo, Rafael; Varadé, Jezabel; Urcelay, Elena; Alcina, Antonio (Oxford University Pres, 2015-10-01)
      Several variants in strong linkage disequilibrium (LD) at the SP140 locus have been associated with multiple sclerosis (MS), Crohn's disease (CD) and chronic lymphocytic leukemia (CLL). To determine the causal polymorphism, ...