Browsing by Subject "AGING"

Now showing items 1-2 of 2

    • Thumbnail

      Epitope mapping of antibodies to alpha-synuclein in LRRK2 mutation carriers, idiopathic Parkinson disease patients, and healthy controls 

      Alvarez-Castelao, Beatriz; Gorostidi, Ana; Ruíz-Martínez, Javier; López de Munain Arregui, Adolfo José; Castaño, José G. (Frontiers Research Foundation, 2014-07-15)
      Alpha-synuclein (Snca) plays a major role in Parkinson disease (PD). Circulating anti-Snca antibodies has been described in PD patients and healthy controls, but they have been poorly characterized. This study was designed ...
    • Thumbnail

      Muscle wasting in myotonic dystrophies: a model of premature aging 

      Mateos Aierdi, Alba Judith; Goicoechea, María; Aiastui, Ana; Fernández-Torrón, Roberto; García-Puga, Mikel; Matheu Fernández, Ander; López de Munain Arregui, Adolfo José (Frontiers Research Foundation, 2015-07-09)
      Myotonic dystrophy type 1 (DM1 or Steinert's disease) and type 2 (DM2) are multisystem disorders of genetic origin. Progressive muscular weakness, atrophy and myotonia are the most prominent neuromuscular features of these ...