Browsing by Author "Ophel, Jasper"

Now showing items 1-1 of 1

    • Thumbnail

      Engineering pan–HIV-1 neutralization potency through multispecific antibody avidity 

      Rujas Díez, Edurne; Cui, Hong; Burnie, Jonathan; Burn Aschner, Clare; Zhao, Tiantian; Insausti González, Sara; Muthuraman, Krithika; Semesi, Anthony; Ophel, Jasper; Nieva Escandón, José Luis; Seaman, Michael S.; Guzzo, Christina; Treanor, Bebhinn; Julien, Jean-Philippe (National Academy of Sciences of the United States of America, 2022-01-25)
      Deep mining of B cell repertoires of HIV-1-infected individuals has resulted in the isolation of dozens of HIV-1 broadly neutralizing antibodies (bNAbs). Yet, it remains uncertain whether any such bNAbs alone are sufficiently ...