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dc.contributor.authorAlonso Alconada, Daniel ORCID
dc.contributor.authorÁlvarez Díaz, Antonia Ángeles
dc.contributor.authorArteaga Cabeza, Olatz
dc.contributor.authorMartínez Ibargüen, Agustín
dc.contributor.authorHilario Rodríguez, Enrique
dc.date.accessioned2014-01-28T19:31:07Z
dc.date.available2014-01-28T19:31:07Z
dc.date.issued2013-04-29
dc.identifier.citationInternational Journal of Molecular Sciences 14(5) : 9379-9395 (2013)es
dc.identifier.issn1422-0067
dc.identifier.urihttp://hdl.handle.net/10810/11315
dc.description17 p.es
dc.description.abstractOne of the most common causes of mortality and morbidity in children is perinatal hypoxia-ischemia (HI). In spite of the advances in neonatology, its incidence is not diminishing, generating a pediatric population that will require an extended amount of chronic care throughout their lifetime. For this reason, new and more effective neuroprotective strategies are urgently required, in order to minimize as much as possible the neurological consequences of this encephalopathy. In this sense, interest has grown in the neuroprotective possibilities of melatonin, as this hormone may help to maintain cell survival through the modulation of a wide range of physiological functions. Although some of the mechanisms by which melatonin is neuroprotective after neonatal asphyxia remain a subject of investigation, this review tries to summarize some of the most recent advances related with its use as a therapeutic drug against perinatal hypoxic-ischemic brain injury, supporting the high interest in this indoleamine as a future feasible strategy for cerebral asphyctic events.es
dc.language.isoenges
dc.publisherMDPI AGes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectmelatonines
dc.subjectneuroprotectiones
dc.subjecthypoxia-ischemiaes
dc.subjectnewbornes
dc.titleNeuroprotective Effect of Melatonin: A Novel Therapy against Perinatal Hypoxia-Ischemiaes
dc.typeinfo:eu-repo/semantics/articlees
dc.rights.holder© 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).es
dc.relation.publisherversionhttp://www.mdpi.com/1422-0067/14/5/9379es
dc.identifier.doi10.3390/ijms14059379
dc.departamentoesBiología celular e histologíaes_ES
dc.departamentoeuZelulen biologia eta histologiaes_ES
dc.subject.categoriaCATALYSIS
dc.subject.categoriaSPECTROSCOPY
dc.subject.categoriaMOLECULAR BIOLOGY
dc.subject.categoriaCOMPUTER SCIENCE APPLICATIONS
dc.subject.categoriaCHEMISTRY, PHYSICAL
dc.subject.categoriaCHEMISTRY, ORGANIC
dc.subject.categoriaCHEMISTRY, INORGANIC AND NUCLEAR


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