BackBrowsing Artículos, Comunicaciones, Libros by Author "Sabio, Guadalupe"
Now showing items 1-5 of 5
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Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function
Da Silva Lima, Natalia; Fondevila, Marcos F.; Novoa, Eva; Buqué García, Xabier
; Mercado Gómez, María; Gallet, Sarah; González Rellán, María Jesús; Fernández, Uxia; Loyens, Anne; García Vence, María; Chantada Vázquez, María del Pilar; Bravo López, Susana Belén; Marañón, Patricia; Senra, Ana; Escudero González, Adriana; Leiva, Magdalena; Guallar, Diana; Fidalgo, Miguel; Gomes, Pedro; Claret, Marc; Sabio, Guadalupe; Varela Rey, Marta; Cardoso Delgado, Teresa de Jesús; Montero Vallejo, Rocío; Ampuero Herrojo, Javier; López, Miguel; Diéguez González, Carlos; Herrero, Laura; Serra, Dolors; Schwaninger, Markus; Prevot, Vincent; Gallego Durán, Rocío; Romero Gómez, Manuel; Iruzubieta, Paula; Crespo, Javier; Martínez Chantar, María Luz ; García Monzón, Carmelo; González Rodríguez, Águeda; ; Nogueiras Pozo, Rubén (Elsevier, 2022-01)
[EN]Background & Aims: Autophagy-related gene 3 (ATG3) is an enzyme mainly known for its actions in the LC3 lipidation process, which is essential for autophagy. Whether ATG3 plays a role in lipid metabolism or contributes ... -
Magnesium Accumulation Upon Cyclin M4 Silencing Activates Microsomal Triglyceride Transfer Protein Improving NASH
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; Martínez Chantar, María Luz (Elsevier, 2021-07)
Background & Aims: Perturbations of intracellular magnesium (Mg2+) homeostasis have implications for cell physiology. The cyclin M family, CNNM, perform key functions in the transport of Mg2+ across cell membranes. Herein, ... -
Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis
; Buqué García, Xabier; ; ; ; ; ; ; ; ; ; ; ; ; ; ; Aurrekoetxea Galindo, Igor ; ; ; ; ; ; ; Bañales Asurmendi, Jesús María ; ; ; Martínez Chantar, María Luz ; ; (Nature, 2022)
Altered methionine metabolism is associated with weight gain in obesity. The methionine adenosyltransferase (MAT), catalyzing the first reaction of the methionine cycle, plays an important role regulating lipid metabolism. ... -
Mitochondrial bioenergetics boost macrophage activation, promoting liver regeneration in metabolically compromised animals
Goikoetxea Usandizaga, Naroa; ; Delgado, Teresa C.; Simón Espinosa, Jorge; Fernández Ramos, David; Barriales, Diego; Cornide, María E.; Jiménez, Mónica; Pérez Redondo, Marina; Lachiondo Ortega, Sofía; Rodríguez Agudo, Rubén; Bizkarguenaga, Maider; Diego Zalamea, Juan; Pasco, Samuel T.; Caballero Díaz, Daniel; Alfano, Benedetta; Bravo Garmendia, Miren; González Recio, Irene; Mercado Gómez, María; Gil Pitarch, Clàudia; Mabe Alvarez, Jon; Gracia Sancho, Jordi; Abecia Aliende, Leticia; Lorenzo, Oscar; Martín Sanz, Paloma; Abrescia, Nicola A.G.; Sabio, Guadalupe; Rincón, Mercedes; Anguita Castillo, Juan de Dios; Miñambres, Eduardo; Martín, César; Berenguer, Marina; Fabregat, Isabel; Casado, Marta; Peralta, Carmen; Varela Rey, Marta; Martínez Chantar, María Luz (Wiley, 2022-03)
[EN] Background and Aims Hepatic ischemia-reperfusion injury (IRI) is the leading cause of early posttransplantation organ failure as mitochondrial respiration and ATP production are affected. A shortage of donors has ... -
p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1
; ; ; ; ; ; Rodríguez, Elena; ; ; ; ; ; ; ; ; ; ; ; ; ; (Public Library Science, 2021-11-10)
[EN]During the first weeks of postnatal heart development, cardiomyocytes undergo a major adaptive metabolic shift from glycolytic energy production to fatty acid oxidation. This metabolic change is contemporaneous to the ...