Now showing items 1-20 of 32

    • Thumbnail

      Acidosis tubular renal distal hereditaria: correlación genotípica, evolución a largo plazo y nuevas perspectivas terapéuticas 

      Gómez Conde, Sara; García Castaño, Alejandro; Aguirre, Mireia; Herrero Goñi, María; Gondra Sangroniz, Leire; Castaño González, Luis Antonio ORCID; Madariaga Domínguez, Leire ORCID (Elsevier, 2021-07)
      [ES] La acidosis tubular renal distal (ATRD) es una enfermedad rara que se debe al fallo del proceso normal de acidificación de la orina a nivel tubular distal y colector. Se caracteriza por una acidosis metabólica ...
    • Thumbnail

      Adiponectin, leptin, and IGF-1 are useful diagnostic and stratification biomarkers of NAFLD 

      Marques, Vanda; Afonso, Marta Bento; Bierig, Nina; Duarte-Ramos, Filipa; Santos Laso, Álvaro; Jiménez Agüero, Raúl; Eizaguirre Letamendia, Emma; Bujanda Fernández de Pierola, Luis ORCID; Pareja Megía, María J.; Luís, Rita; Costa, Adília; Machado, Mariana Verdelho; Alonso, Cristina; Arretxe Oliden, Enara; Alustiza Echeberria, José María; Krawczyk, Marcin; Lammert, Frank; Tiniakos, Dina G.; Flehmig, Bertram; Cortez-Pinto, Helena; Bañales Asurmendi, Jesús María ORCID; Castro, Rui E.; Normann, Andrea; Rodrigues, Cecilia M. P. (Frontiers Media, 2021-06-23)
      [EN] Background: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease where liver biopsy remains the gold standard for diagnosis. Here we aimed to evaluate the role of circulating adiponectin, ...
    • Thumbnail

      Alérgenos candidatos para ser incluidos en la serie estándar española a partir de los datos del Registro Español de Dermatitis de Contacto 

      Hernández Fernández, Carlos Pelayo; Mercader García, Pedro; Silvestre Salvador, Juan Francisco; Sánchez Pérez, Javier; Fernández Redondo, Virginia; Miquel Miquel, Francisco Javier; Ortíz de Frutos, Francisco Javier; Gatica Ortega, María Elena; Mora Fernández, Verónica; Giménez Arnau, Anna María; Zaragoza Ninet, Violeta; González Pérez, Ricardo; Sanz Sánchez, Tatiana; Pastor Nieto, María Antonia; Serra Baldrich, Esther; Córdoba Guijarro, Susana; Heras Mendaza, Felipe; Ruiz González, Inmaculada; Rodríguez Serna, Mercedes; Hervella Garcés, Marcos; Gallego Descalzo, Miguel Ángel; García Doval, Ignacio; Borrego Hernando, Leopoldo (Elsevier, 2021-10)
      [EN]Background: Standard patch test series must be updated using objective data on allergen sensitization. The Spanish standard series was last updated in 2016 and the European series in 2019, and the inclusion of several ...
    • Thumbnail

      Assessing the Utility and Patient Satisfaction of Virtual Retina Clinics During COVID-19 Pandemic 

      Juaristi, Leire; Irigoyen, Cristina; Chapartegui, Jaione; Guibelalde González, Ane; Mar Medina, Javier (Dove Medical Press, 2022)
      [EN] Purpose: To explore whether the virtual retina clinic (VRC) has been a useful and safe platform for monitoring retinal diseases during the COVID-19 pandemic and assessing patient satisfaction. Methods: A prospective ...
    • Thumbnail

      Association of TYR SNP rs1042602 with Melanoma Risk and Prognosis 

      Sevilla Mambrilla, Arrate ORCID; Sánchez Díez, Ana; Cobo, Sofía; Izagirre Arribalzaga, Neskuts ORCID; Martínez Cadenas, Conrado; Martí Laborda, Rosa María; Puértolas, Teresa; de Unamuno, Blanca; Bañuls, José; Izu Belloso, Rosa María; Gardeazabal García, Jesús; Asumendi Mallea, Aintzane ORCID; Boyano López, María Dolores ORCID; Alonso Alegre, Santos ORCID (MDPI, 2022-12-01)
      Cutaneous melanoma is the most aggressive of skin tumors. In order to discover new biomarkers that could help us improve prognostic prediction in melanoma patients, we have searched for germline DNA variants associated ...
    • Thumbnail

      Behavior of hyperreflective foci in non- infectious uveitic macular edema, a 12- month follow-up prospective study 

      Berasategui, Bárbara; Fonollosa Calduch, Alejandro; Artaraz Beobide, Joseba Iñaki; Ruiz Arruza, Ioana; Ríos, José; Matas, Jessica; Llorenç, Victor; Diaz-Valle, David; Sastre-Ibañez, Marina; Arriola-Villalobos, Pedro; Adan, Alfredo (Biomed Central, 2018-07-20)
      Background: Hyperreflective foci have been described in OCT imaging of patients with retinal vascular diseases. It has been suggested that they may play a role as a prognostic factor of visual outcomes in these diseases. ...
    • Thumbnail

      Comparative lipidomic analysis of mammalian retinal ganglion cells and Muller glia in situ and in vitro using High-Resolution Imaging Mass Spectrometry 

      Pereiro Díez, Xandra ORCID; Fernández, Roberto; Barreda Gómez, Gabriel; Ruzafa Andrés, Noelia ORCID; Acera Osa, Arantxa; Araiz Iribarren, José Javier; Astigarraga Arribas, Egoitz; Vecino Cordero, Elena ORCID (Nature, 2020-11-18)
      In order to better understand retinal physiology, alterations to which underlie some ocular diseases, we set out to establish the lipid signature of two fundamental cell types in the retina, Muller Glia and Retinal Ganglion ...
    • Thumbnail

      Comparative study of the lipid profile of tears and plasma enriched in growth factors. 

      Acera Osa, Arantxa; Abad García, Beatriz; Pereiro Díez, Xandra ORCID; Rodríguez, Francisco David; Ruzafa Andrés, Noelia ORCID; Durán de la Colina, Juan Antonio; Vecino Cordero, Elena ORCID (Elsevier, 2022-06)
      [EN] The Tear Film Lipid Layer (TFLL) acts primarily as an interface between the aqueous layer and air. Tear film lipid is composed of a thin layer of polar lipids that interact with the secretory layer of the underlying ...
    • Thumbnail

      Computational and Experimental Evaluation of the Immune Response of Neoantigens for Personalized Vaccine Design 

      Malaina Celada, Iker ORCID; González Melero, Lorena; Martínez Fernández, Luis ORCID; Salvador Martínez, Aiala ORCID; Sánchez Díez, Ana; Asumendi Mallea, Aintzane ORCID; Margareto, Javier; Carrasco Pujante, José; Legarreta Solaguren, Leire; García, María Asunción; Pérez Pinilla, Martín Blas ORCID; Izu Belloso, Rosa María; Martínez de la Fuente Martínez, Ildefonso Abel; Igartua Olaechea, Manuela ORCID; Alonso Alegre, Santos ORCID; Hernández Martín, Rosa María ORCID; Boyano López, María Dolores ORCID (MDPI, 2023-05-19)
      In the last few years, the importance of neoantigens in the development of personalized antitumor vaccines has increased remarkably. In order to study whether bioinformatic tools are effective in detecting neoantigens that ...
    • Thumbnail

      Dabrafenib for cutaneous melanoma infiltrating the vitreous: regression of metastasis and occurrence of uveitis as a secondary effect 

      Fonollosa Calduch, Alejandro; Vargas Kelsh, Jose Gabriel; Garay Aramburu, Gonzaga ORCID; Saiz, Angel; Zabalza Estévez, Ignacio; Fernández, Ricardo (Springer, 2017-07-25)
      Intraocular metastasis of cutaneous melanoma is extremely infrequent. This typically occurs in advanced metastatic disease and has a poor survival prognosis. The most frequent reported treatment is radiotherapy. BRAF ...
    • Thumbnail

      Differential Distribution of RBPMS in Pig, Rat, and Human Retina after Damage 

      Pereiro Díez, Xandra ORCID; Ruzafa Andrés, Noelia ORCID; Urcola Carrera, Javier Haritz ORCID; Sharma, Sansar C.; Vecino Cordero, Elena ORCID (MDPI, 2020-12-07)
      RNA binding protein with multiple splicing (RBPMS) is expressed exclusively in retinal ganglion cells (RGCs) in the retina and can label all RGCs in normal retinas of mice, rats, guinea pigs, rabbits, cats, and monkeys, ...
    • Thumbnail

      Do Nutritional Supplements Have a Role in Age Macular Degeneration Prevention? 

      Pinazo-Durán, Maria D.; Gómez-Ulla, Francisco; Arias, Luis; Araiz Iribarren, José Javier; Casaroli-Marano, Ricardo; García-Medina, Jose J.; López-Gálvez, María Isabel; Manzanas, Lucía; Salas, Anna; Zapata, Miguel; Diaz-Llopis, Manuel; García-Layana, Alfredo (Hindawi Publishing, 2014)
      Purpose. To review the proposed pathogenic mechanisms of age macular degeneration (AMD), as well as the role of antioxidants (AOX) and omega-3 fatty acids (omega-3) supplements in AMD prevention. Materials and Methods. ...
    • Thumbnail

      Effect of Neonatal Asphyxia on the Impairment of the Auditory Pathway by Recording Auditory Brainstem Responses in Newborn Piglets: A New Experimentation Model to Study the Perinatal Hypoxic-Ischemic Damage on the Auditory Syste 

      Álvarez, Francisco José; Revuelta Aramberri, Miren ORCID; Santaolalla Montoya, Francisco ORCID; Álvarez Díaz, Antonia Ángeles; Lafuente, Héctor; Arteaga Cabeza, Olatz; Alonso Alconada, Daniel ORCID; Sánchez del Rey, Ana Salomé; Hilario Rodríguez, Enrique; Martínez Ibargüen, Agustín (Public Library Science, 2015-05-26)
      Introduction Hypoxia-ischemia (HI) is a major perinatal problem that results in severe damage to the brain impairing the normal development of the auditory system. The purpose of the present study is to study the effect ...
    • Thumbnail

      Efficacy, safety and cost-effectiveness of methotrexate, adalimumab or their combination in non-infectious non-anterior uveitis: a protocol for a multicentre, randomised, parallel three arms, active-controlled, phase III open label with blinded outcome assessment study 

      CoTHEIA Study Group; Fonollosa Calduch, Alejandro (BMJ, 2022-03-22)
      [EN] INTRODUCTION: Non-infectious uveitis include a heterogeneous group of sight-threatening and incapacitating conditions. Their correct management sometimes requires the use of immunosuppressive drugs (ISDs), prescribed ...
    • Thumbnail

      Evaluation of 10 AMD Associated Polymorphisms as a Cause of Choroidal Neovascularization in Highly Myopic Eyes 

      Velázquez Villoria, Alvaro; Recalde, Sergio; Anter, Jaouad; Bezunartea, Jaione; Hernández Sánchez, Maria; García García, Laura; Alonso, Elena; Ruiz Moreno, José María; Araiz Iribarren, José Javier; Fernández Robredo, Patricia; García Layana, Alfredo (Public Library Science, 2016-09-19)
      Choroidal neovascularization (CNV) commonly occurs in age related macular degeneration and pathological myopia patients. In this study we conducted a case-control prospective study including 431 participants. The aim of ...
    • Thumbnail

      Evaluation of Macular Thickness Changes after Uncomplicated Phacoemulsification Surgery in Healthy Subjects and Diabetic Patients without Retinopathy by Spectral Domain OCT 

      García Gómez de Segura, Mikel; Martín Arroyuelos, Ana María ORCID; Pinilla, Isabel; Araiz Iribarren, José Javier (MDPI, 2022-12-07)
      Purpose: To assess differences in the evolution of macular thickness after uncomplicated phacoemulsification surgery between non-diabetic subjects and patients with diabetes mellitus (DM) without diabetic retinopathy (DR), ...
    • Thumbnail

      Implementation of a Surgery Congress for Medical Students to Learn Transversal Competences. A Case of Student-Led Teaching Activity 

      Herrero de la Parte, Borja; Santaolalla Sánchez, María; Santaolalla Sánchez, Francisco Javier; García-Alonso Montoya, Ignacio ORCID; Santaolalla Montoya, Francisco ORCID; Sánchez del Rey, Ana (MDPI, 2021-09-14)
      Background: A dynamic training approach close to clinical work and research is highly requested by health sciences students. The aim of this paper is to present the organizational model of a student-promoted and student-managed ...
    • Thumbnail

      Incidence and Risk Factors Affecting the Recurrence of Primary Retinal Detachment in a Tertiary Hospital in Spain 

      Irigoyen Laborra, Cristina ORCID; Goikoetxea-Zubeldia, Ainhoa; Sanchez-Molina, Jorge ORCID; Amenabar Alonso, Asier; Ruiz-Miguel, Miguel; Iglesias-Gaspar, Maria Teresa (MDPI, 2022)
      (1) Objective: To determine the incidence, visual outcomes and risk factors associated with the recurrence of primary retinal detachment (RD) in a tertiary hospital. (2) Methods: A retrospective observational study was ...
    • Thumbnail

      Involvement of ANXA5 and ILKAP in Susceptibility to Malignant Melanoma 

      Arroyo Berdugo, Yoana; Alonso Alegre, Santos ORCID; Ribas, Gloria; Ibarrola Villava, Maider; Peña-Chilet, María; Martínez-Cadenas, Conrado; Gardeazabal García, Jesús; Ratón Nieto, Juan Antonio; Sánchez Díez, Ana; Careaga Alzaga, Jesús María; Pérez-Yarza Pérez-Irezabal, Gorka ORCID; Carretero, Gregorio; Martín-González, Manuel; Gómez-Fernández, Cristina; Nagore, Eduardo; Asumendi Mallea, Aintzane ORCID; Boyano López, María Dolores ORCID (Public Library Science, 2014-04-17)
      Single nucleotide-polymorphisms (SNPs) are a source of diversity among human population, which may be responsible for the different individual susceptibility to diseases and/or response to drugs, among other phenotypic ...
    • Thumbnail

      Melanoma and Nevi Subtype Histopathological Characterization with Optical Coherence Tomography 

      Saratxaga, Cristina L.; Asumendi Mallea, Aintzane ORCID; Gardeazabal García, Jesús; Izu Belloso, Rosa María; Sánchez Díez, Ana; Cancho Galán, Goikoane; Morales González, María Celia; Lage, Sergio; Boyano López, María Dolores ORCID; Conde, Olga M.; Garrote Contreras, Estíbaliz (MDPI, 2023-02-23)
      Background: Melanoma incidence has continued to rise in the latest decades, and the forecast is not optimistic. Non-invasive diagnostic imaging techniques such as optical coherence tomography (OCT) are largely studied; ...