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Magnetic Cross-Linked Enzyme Aggregates (mCLEAs) of Candida antarctica Lipase: An Efficient and Stable Biocatalyst for Biodiesel Synthesis
(Public Library Science, 2014-12-31)
Enzyme-catalyzed production of biodiesel is the object of extensive research due to the global shortage of fossil fuels and increased environmental concerns. Herein we report the preparation and main characteristics of a ...
Detection of Atomic Scale Changes in the Free Volume Void Size of Three-Dimensional Colorectal Cancer Cell Culture Using Positron Annihilation Lifetime Spectroscopy
Axpe Iza, Eneko; López Euba, Tamara; Castellanos Rubio, Ainara; Mérida Sanz, David; ; Plaza-Izurieta, Leticia; Fernández-Jiménez, Nora; Plazaola Muguruza, Fernando 
; (Public Library of Science, 2014-01-02)
; (Public Library of Science, 2014-01-02)
Positron annihilation lifetime spectroscopy (PALS) provides a direct measurement of the free volume void sizes in polymers and biological systems. This free volume is critical in explaining and understanding physical and ...
Early Functional Deficit and Microglial Disturbances in a Mouse Model of Amyotrophic Lateral Sclerosis
(Public Library of Science, 2012-04-25)
Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by selective motoneurons degeneration. There is today no clear-cut pathogenesis sequence nor any treatment. However growing ...
Biotic vs. Abiotic Control of Decomposition: A Comparison of the Effects of Simulated Extinctions and Changes in Temperature
Boyero González, María Luz ; Cardinale, Bradley J.; Bastian, Mikis; Pearson, Richard G. (Public Library of Science, 2014-01)
; Cardinale, Bradley J.; Bastian, Mikis; Pearson, Richard G. (Public Library of Science, 2014-01)
The loss of species is known to have significant effects on ecosystem functioning, but only recently has it been recognized that species loss might rival the effects of other forms of environmental change on ecosystem ...
Temperature-and pH-Sensitive Nanohydrogels of Poly(N-Isopropylacrylamide) for Food Packaging Applications: Modelling the Swelling-Collapse Behaviour
(Public Library Science, 2014-02-10)
Temperature-sensitive poly(N-isopropylacrylamide) (PNIPA) nanohydrogels were synthesized by nanoemulsion polymerization in water-in-oil systems. Several cross-linking degrees and the incorporation of acrylic acid as comonomer ...
α2,3-Sialyltransferase ST3Gal III Modulates Pancreatic Cancer Cell Motility and Adhesion In Vitro and Enhances Its Metastatic Potential In Vivo
Pérez-Garay, Marta; Arteta Ruiz, Beatriz ; Pagès, Lluís; De Llorens, Rafael; De Bolòs, Carme; Vidal Vanaclocha, Fernando; Peracaula, Rosa (Public Library of Science, 2010-09-01)
; Pagès, Lluís; De Llorens, Rafael; De Bolòs, Carme; Vidal Vanaclocha, Fernando; Peracaula, Rosa (Public Library of Science, 2010-09-01)
Background: Cell surface sialylation is emerging as an important feature of cancer cell metastasis. Sialyltransferase expression has been reported to be altered in tumours and may account for the formation of sialylated ...
Optimal Resting-Growth Strategies of Microbial Populations in Fluctuating Environments
(Public Library of Science, 2011-04-15)
Bacteria spend most of their lifetime in non-growing states which allow them to survive extended periods of stress and starvation. When environments improve, they must quickly resume growth to maximize their share of limited ...
High-Throughput Sequencing of microRNAs in Peripheral Blood Mononuclear Cells: Identification of Potential Weight Loss Biomarkers
Milagro Yoldi, Fermín I.; Miranda Gómez, Jonatan ; Portillo Baquedano, María Puy ; Fernández Quintela, Alfredo ; Campión Zabalza, Javier; Martínez, José Alfredo (Public Library of Science (PLoS), 2013)
; Portillo Baquedano, María Puy ; Fernández Quintela, Alfredo ; Campión Zabalza, Javier; Martínez, José Alfredo (Public Library of Science (PLoS), 2013)
INTRODUCTION: MicroRNAs (miRNAs) are being increasingly studied in relation to energy metabolism and body composition homeostasis. Indeed, the quantitative analysis of miRNAs expression in different adiposity conditions ...
The Cryo-EM Structure of a Complete 30S Translation Initiation Complex from Escherichia coli
(Public Library of Science, 2011-07-05)
Formation of the 30S initiation complex (30S IC) is an important checkpoint in regulation of gene expression. The selection of mRNA, correct start codon, and the initiator fMet-tRNA(fMet) requires the presence of three ...
Pivoting between Calmodulin Lobes Triggered by Calcium in the Kv7.2/Calmodulin Complex
Alaimo Campi, Alessandro ; Alberdi González, Araitz; Gomis Pérez, Carolina; Fernández Orth, Juncal; Bernardo Seisdedos, Ganeko; Malo de la Fuente, Covadonga; Millet Aguilar-Galindo, Oscar; Areso Goiricelaya, María Pilar; Villarroel Muñoz, Álvaro (Public Library Science, 2014-01-28)
; Alberdi González, Araitz; Gomis Pérez, Carolina; Fernández Orth, Juncal; Bernardo Seisdedos, Ganeko; Malo de la Fuente, Covadonga; Millet Aguilar-Galindo, Oscar; Areso Goiricelaya, María Pilar; Villarroel Muñoz, Álvaro (Public Library Science, 2014-01-28)
Kv7.2 (KCNQ2) is the principal molecular component of the slow voltage gated M-channel, which strongly influences neuronal excitability. Calmodulin (CaM) binds to two intracellular C-terminal segments of Kv7.2 channels, ...