BackBrowsing Artículos by Subject "BIOCHEMISTRY AND MOLECULAR BIOLOGY"
Now showing items 21-40 of 176
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Association between CASP8-652 6N Del Polymorphism (rs3834129) and Colorectal Cancer Risk: Results from a Multi-Centric Study
Pardini, Barbara; Verderio, Paolo; Pizzamiglio, Sara; Nici, Carmela; Maiorana, Maria Valeria; Naccarati, Alessio; Vodickova, Ludmila; Vymetalkova, Veronika; Veneroni, Silvia; Daidone, Maria Grazia; Ravagnani, Fernando; Bianchi, Tiziana; Bujanda Fernández de Pierola, Luis
; Carracedo, Angel; Castells, Antoni; Ruiz Ponte, Clara; Morreau, Hans; Howarth, Kimberley; Jones, Angela; Castellví-Bel, Sergi; Li, Li; Tomlinson, Ian; Van Wezel, Tom; Vodicka, Pavel; Radice, Paolo; Peterlongo, Paolo; EPICOLON Consortium (Public Library Science, 2014-01)
The common 2652 6N del variant in the CASP8 promoter (rs3834129) has been described as a putative low-penetrance risk factor for different cancer types. In particular, some studies suggested that the deleted allele (del) ... -
Autophagic Marker MAP1LC3B Expression Levels Are Associated with Carotid Atherosclerosis Symptomatology
(Public Library Science, 2014-12-12)Objectives: The mechanism by which atheroma plaque becomes unstable is not completely understood to date but analysis of differentially expressed genes in stable versus unstable plaques may provide clues. This will be ... -
Biotic vs. Abiotic Control of Decomposition: A Comparison of the Effects of Simulated Extinctions and Changes in Temperature
Boyero González, María Luz; Cardinale, Bradley J.; Bastian, Mikis; Pearson, Richard G. (Public Library of Science, 2014-01)
The loss of species is known to have significant effects on ecosystem functioning, but only recently has it been recognized that species loss might rival the effects of other forms of environmental change on ecosystem ... -
Birth Weight, Working Memory and Epigenetic Signatures in IGF2 and Related Genes: A MZ Twin Study
González Pinto Arrillaga, Ana María; Córdova-Palomera, Aldo; Alemany, Silvia; Fatjó-Vilas, Mar; Goldberg, Ximena; Leza, Juan Carlos; Nenadic, Igor; Fañanás, Lourdes (Public Library Science, 2014-08-29)
Neurodevelopmental disruptions caused by obstetric complications play a role in the etiology of several phenotypes associated with neuropsychiatric diseases and cognitive dysfunctions. Importantly, it has been noticed that ... -
Ca2+ Influx and Tyrosine Kinases Trigger Bordetella Adenylate Cyclase Toxin (ACT) Endocytosis. Cell Physiology and Expression of the CD11b/CD18 Integrin Major Determinants of the Entry Route
Belloso Uribe, Kepa; ; Etxebarria, Aitor; González Bullón, David; Gómez Bilbao, Geraxane; (Public Library Publishing, 2013-09)
Humans infected with Bordetella pertussis, the whooping cough bacterium, show evidences of impaired host defenses. This pathogenic bacterium produces a unique adenylate cyclase toxin (ACT) which enters human phagocytes and ... -
Calpain-Mediated Processing of Adenylate Cyclase Toxin Generates a Cytosolic Soluble Catalytically Active N-Terminal Domain
(Public Library Publishing, 2013-06)Bordetella pertussis, the whooping cough pathogen, secretes several virulence factors among which adenylate cyclase toxin (ACT) is essential for establishment of the disease in the respiratory tract. ACT weakens host ... -
Candida albicans Increases Tumor Cell Adhesion to Endothelial Cells In Vitro: Intraspecific Differences and Importance of the Mannose Receptor
; Arteta Ruiz, Beatriz; Abad Díaz de Cerio, Ana ; ; Antorán Díaz, Aitziber ; Márquez Clavijo, Joana ; ; (PloS ONE, 2013-01-02)
The dimorphic fungus Candida albicans is able to trigger a cytokine-mediated pro-inflammatory response that increases tumor cell adhesion to hepatic endothelium and metastasis. To check the intraspecific differences in ... -
Classifier Subset Selection for the Stacked Generalization Method Applied to Emotion Recognition in Speech
; Sierra Araujo, Basilio; Arruti Illarramendi, Andoni ; ; Garay Vitoria, Néstor (MDPI, 2016-01)
In this paper, a new supervised classification paradigm, called classifier subset selection for stacked generalization (CSS stacking), is presented to deal with speech emotion recognition. The new approach consists of an ... -
Combined Fluorescent-Chromogenic In Situ Hybridization for Identification and Laser Microdissection of Interphase Chromosomes
Paz Gandiaga, Nerea; Zabala, Amaia; Royo, Félix; García-Orad Carles, África; Zugaza Gurruchaga, José Luis ; Parada, Luis A. (Public Library of Science, 2013)
Chromosome territories constitute the most conspicuous feature of nuclear architecture, and they exhibit non-random distribution patterns in the interphase nucleus. We observed that in cell nuclei from humans with Down ... -
Comparison of the Transcriptional Profiles of Melanocytes from Dark and Light Skinned Individuals under Basal Conditions and Following Ultraviolet-B Irradiation
; ; García de Galdeano Zaldivar, María Alicia; Boyano López, María Dolores ; ; ; ; Izagirre Arribalzaga, Neskuts ; De la Rúa Vaca, Concepción ; Alonso Alegre, Santos (Public Library Science, 2015-08-05)
We analysed the whole-genome transcriptional profile of 6 cell lines of dark melanocytes (DM) and 6 of light melanocytes (LM) at basal conditions and after ultraviolet-B (UVB) radiation at different time points to investigate ... -
Contribution of Pannexin1 to Experimental Autoimmune Encephalomyelitis
Lutz, Sarah E.; González Fernández, Estibaliz; Chara Ventura, Juan Carlos; Pérez Samartín, Alberto Luis; Tarassishin, Leonid; Negoro, Hiromitsu; Patel, Naman K.; Suadicani, Sylvia O.; Lee, Sunhee C.; ; Scemes, Eliana (Public Library of Science, 2013-06)
Pannexin1 (Panx1) is a plasma membrane channel permeable to relatively large molecules, such as ATP. In the central nervous system (CNS) Panx1 is found in neurons and glia and in the immune system in macrophages and T-cells. ... -
Data Gathering Bias: Trait Vulnerability to Psychotic Symptoms?
Catalán Alcántara, Ana; Simons, Claudia J. P.; Bustamante Madariaga, Sonia; Olazabal Eizaguirre, Nora; Ruiz Parra, Eduardo; González de Artaza Lavesa, Maider; Penas, Alberto; Maurottolo, Claudio; González, Andrea; González Torres, Miguel Ángel (Public Library Science, 2015-07-06)
Background Jumping to conclusions (JTC) is associated with psychotic disorder and psychotic symptoms. If JTC represents a trait, the rate should be (i) increased in people with elevated levels of psychosis proneness ... -
Data Preprocessing and Model Design for Medicine Problems
(Hindawi Publishing Corporation, 2013)... -
Dealing with the Effects of Sensor Displacement in Wearable Activity Recognition
(MDPI, 2014-06)Most wearable activity recognition systems assume a predefined sensor deployment that remains unchanged during runtime. However, this assumption does not reflect real-life conditions. During the normal use of such systems, ... -
Depression of Serotonin Synaptic Transmission by the Dopamine Precursor L-DOPA
; ; Llamosas Muñozguren, Nerea; ; (Cell Press, 2015-08-11)
Imbalance between the dopamine and serotonin (5-HT) neurotransmitter systems has been implicated in the comorbidity of Parkinson's disease (PD) and psychiatric disorders. L-DOPA, the leading treatment of PD, facilitates ... -
Design and Development of a Low-Cost Optical Current Sensor
; Casado, Luciano; Aldabaldetreku Etxeberria, Gotzon; Montero, Alfonso; Zubia, Eneko; Durana Apaolaza, Gaizka (MDPI, 2013-10)
In this paper we demonstrate the design of a low-cost optical current sensor. The sensor principle is the Faraday rotation of a light beam through a magneto-optical material, SF2, when a magnetic field is present. The ... -
Design and implementation of a cloud computing adoption decision tool: Generating a cloud road
Bildosola Agirregomezkorta, Iñaki; Río Belver, Rosa María ; Cilleruelo Carrasco, Ernesto Jesús ; Garechana Anacabe, Gaizka (Public Library of Science, 2015-07-31)
Migrating to cloud computing is one of the current enterprise challenges. This technology provides a new paradigm based on "on-demand payment" for information and communication technologies. In this sense, the small and ... -
Design of a Sensor Based on Plastic Optical Fibre (POF) to Measure Fluid Flow and Turbidity
Aiestaran Matxinandiarena, Pedro María; Arrue Aramburu, Juan Antonio; (MDPI, 2009-05)
Although many optical fibre applications are based on their capacity to transmit optical signals with low losses, it can also be desirable for the optical fibre to be strongly affected by a certain physical parameter in ... -
Detection of Atomic Scale Changes in the Free Volume Void Size of Three-Dimensional Colorectal Cancer Cell Culture Using Positron Annihilation Lifetime Spectroscopy
Axpe Iza, Eneko; López Euba, Tamara; Castellanos Rubio, Ainara; Mérida Sanz, David; ; Plaza-Izurieta, Leticia; Fernández-Jiménez, Nora; Plazaola Muguruza, Fernando; Bilbao Catalá, José Ramón (Public Library of Science, 2014-01-02)
Positron annihilation lifetime spectroscopy (PALS) provides a direct measurement of the free volume void sizes in polymers and biological systems. This free volume is critical in explaining and understanding physical and ... -
Differential Micro RNA Expression in PBMC from Multiple Sclerosis Patients
; ; ; Calvo Molinos, Borja; ; ; Inza Cano, Iñaki ; ; ; ; ; (Public Library of Science, 2009-07-20)
Differences in gene expression patterns have been documented not only in Multiple Sclerosis patients versus healthy controls but also in the relapse of the disease. Recently a new gene expression modulator has been identified: ...