Now showing items 21-40 of 157

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      BRAF V600E mutational load as a prognosis biomarker in malignant melanoma 

      Sevilla Mambrilla, Arrate ORCID; Morales González, María Celia; Ezcurra García Unzueta, Pilar Ariadna ORCID; Rasero, Javier; Velasco, Verónica; Cancho Galán, Goikoane; Sánchez Díez, Ana; Mujika, Karmele; Penas Lago, Cristina; Smith Zubiaga, Isabel; Asumendi Mallea, Aintzane ORCID; Cortés Díaz, Jesús María; Boyano López, María Dolores ORCID; Alonso Alegre, Santos ORCID (Public Library Science, 2020-03-13)
      Analyzing the mutational load of driver mutations in melanoma could provide valuable information regarding its progression. We aimed at analyzing the heterogeneity of mutational load of BRAF V600E in biopsies of melanoma ...
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      Cannabinoid-mediated Modulation of Oxidative Stress and Early Inflammatory Response after Hypoxia–Ischemia 

      Alonso-Alconada, Daniel ORCID; Álvarez, Francisco José; Goñi de Cerio, Felipe; Hilario Rodríguez, Enrique; Álvarez Díaz, Antonia Ángeles (MDPI, 2020-02-14)
      In the process of neonatal encephalopathy, oxidative stress and neuroinflammation have a prominent role after perinatal asphyxia. With the exception of therapeutic hypothermia, no therapeutic interventions are available ...
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      Caregiver Characteristics of Adults with Acute Traumatic Brain Injury in the United States and Latin America 

      Juengst, Shannon B.; Perrin, Paul B.; Klyce, Daniel W.; O’Neil-Pirozzi, Therese M.; Herrera, Susan; Wright, Brittany; Lengenfelder, Jean; Lercher, Kirk; Callender, Librada; Arango Lasprilla, Juan Carlos (MDPI, 2022-05)
      Objectives: To compare characteristics of caregivers of adults with acute traumatic brain injury (TBI) in the U.S. and Latin America (Mexico and Colombia). Design: Secondary data analysis of two cohorts. Cohort 1: ...
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      Cell Reprogramming, IPS Limitations, and Overcoming Strategies in Dental Bioengineering 

      Ibarretxe Bilbao, Gaskon ORCID; Álvarez Díaz, Antonia Ángeles; Cañavate Escribano, María Luz; Hilario Rodríguez, Enrique; Aurrekoetxea Campo, Maitane; Unda Rodríguez, Fernando José ORCID (SAGE-Hindawi Access to Research, 2012-03-29)
      The procurement of induced pluripotent stem cells, or IPS cells, from adult differentiated animal cells has the potential to revolutionize future medicine, where reprogrammed IPS cells may be used to repair disease-affected ...
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      Cell-Centric View of Apoptosis and Apoptotic Cell Death-Inducing Antitumoral Strategies 

      Apraiz García, Aintzane ORCID; Boyano López, María Dolores ORCID; Asumendi Mallea, Aintzane ORCID (MDPI, 2011-03-03)
      Programmed cell death and especially apoptotic cell death, occurs under physiological conditions and is also desirable under pathological circumstances. However, the more we learn about cellular signaling cascades, the ...
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      Cellulose and Graphene Based Polyurethane Nanocomposites for FDM 3D Printing: Filament Properties and Printability 

      Larraza Arocena, Izaskun; Vadillo del Ser, Julen; Calvo Correas, Tamara; Tejado, Alvaro; Olza, Sheila; Peña Rodríguez, Cristina; Arbelaiz Garmendia, Aitor; Eceiza Mendiguren, María Aranzazu (MDPI, 2021-03-09)
      3D printing has exponentially grown in popularity due to the personalization of each printed part it offers, making it extremely beneficial for the very demanding biomedical industry. This technique has been extensively ...
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      Changes in Surface Tension of Aqueous Humor in Anterior Segment Ocular Pathologies 

      Cabrerizo Núñez, Francisco Javier; Urcola Carrera, Javier Haritz ORCID; Vecino Cordero, Elena ORCID (MDPI, 2016-09)
      The aim of this study was to identify and determine differences in surface tension (ST) of aqueous humor (AH) in patients with cataract, glaucoma and Fuchs endothelial dystrophy (FED). Two hundred and two samples of AH ...
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      Characterisation of corneas following different time and storage methods for their use as a source of stem-like limbal epithelial cells 

      Romo Valera, Cristina; Pérez Garrastachu, Miguel; Hernáez Moya, Raquel; Rodríguez Astigarraga, Maddalen; Romano Ruiz, Paula; Etxebarria Ecenarro, Jaime; Arluzea de Jauregizar, Jon Andoni ORCID; Andollo Victoriano, María Noelia ORCID (Elsevier, 2021-10)
      The transplantation of expansions of limbal epithelial stem cells (LESC) remains one of the most efficient therapies for the treatment of limbal stem cell deficiency (LSCD) to date. However, the available donor corneas are ...
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      Characteristics of Whale Muller Glia in Primary and Immortalized Cultures 

      Pereiro Díez, Xandra ORCID; Beriain Viguria, Sandra; Rodríguez, Lara; Roiz Valle, David; Ruzafa Andrés, Noelia ORCID; Vecino Cordero, Elena ORCID (Frontiers Media, 2022)
      [EN] Muller cells are the principal glial cells in the retina and they assume many of the functions carried out by astrocytes, oligodendrocytes and ependymal cells in other regions of the central nervous system. Muller ...
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      Chronology protection implementation in analogue gravity 

      Barceló Serón, Carlos; Eguia Sánchez, Jokin; García Moreno, Gerardo; Jannes, Gil (Springer, 2022)
      [EN] Analogue gravity systems offer many insights into gravitational phenomena, both at the classical and at the semiclassical level. The existence of an underlying Minkowskian structure (or Galilean in the non-relativistic ...
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      Comparative lipidomic analysis of mammalian retinal ganglion cells and Muller glia in situ and in vitro using High-Resolution Imaging Mass Spectrometry 

      Pereiro Díez, Xandra ORCID; Fernández, Roberto; Barreda Gómez, Gabriel; Ruzafa Andrés, Noelia ORCID; Acera Osa, Arantxa; Araiz Iribarren, José Javier; Astigarraga Arribas, Egoitz; Vecino Cordero, Elena ORCID (Nature, 2020-11-18)
      In order to better understand retinal physiology, alterations to which underlie some ocular diseases, we set out to establish the lipid signature of two fundamental cell types in the retina, Muller Glia and Retinal Ganglion ...
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      Comparative study of the lipid profile of tears and plasma enriched in growth factors. 

      Acera Osa, Arantxa; Abad García, Beatriz; Pereiro Díez, Xandra ORCID; Rodríguez, Francisco David; Ruzafa Andrés, Noelia ORCID; Durán de la Colina, Juan Antonio; Vecino Cordero, Elena ORCID (Elsevier, 2022-06)
      [EN] The Tear Film Lipid Layer (TFLL) acts primarily as an interface between the aqueous layer and air. Tear film lipid is composed of a thin layer of polar lipids that interact with the secretory layer of the underlying ...
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      Comparison of the Transcriptional Profiles of Melanocytes from Dark and Light Skinned Individuals under Basal Conditions and Following Ultraviolet-B Irradiation 

      López López, Saioa; Smith Zubiaga, Isabel; García de Galdeano Zaldivar, María Alicia ORCID; Boyano López, María Dolores ORCID; García, Oscar; Gardeazabal García, Jesús; Martinez Cadenas, Conrado; Izagirre Arribalzaga, Neskuts ORCID; De la Rúa Vaca, Concepción ORCID; Alonso Alegre, Santos ORCID (Public Library Science, 2015-08-05)
      We analysed the whole-genome transcriptional profile of 6 cell lines of dark melanocytes (DM) and 6 of light melanocytes (LM) at basal conditions and after ultraviolet-B (UVB) radiation at different time points to investigate ...
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      Computational and Experimental Evaluation of the Immune Response of Neoantigens for Personalized Vaccine Design 

      Malaina Celada, Iker ORCID; González Melero, Lorena; Martínez Fernández, Luis ORCID; Salvador Martínez, Aiala ORCID; Sánchez Díez, Ana; Asumendi Mallea, Aintzane ORCID; Margareto, Javier; Carrasco Pujante, José; Legarreta Solaguren, Leire; García, María Asunción; Pérez Pinilla, Martín Blas ORCID; Izu Belloso, Rosa María; Martínez de la Fuente Martínez, Ildefonso Abel; Igartua Olaechea, Manuela ORCID; Alonso Alegre, Santos ORCID; Hernández Martín, Rosa María ORCID; Boyano López, María Dolores ORCID (MDPI, 2023-05-19)
      In the last few years, the importance of neoantigens in the development of personalized antitumor vaccines has increased remarkably. In order to study whether bioinformatic tools are effective in detecting neoantigens that ...
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      Conditioned Medium from H2O2-Preconditioned Human Adipose-Derived Stem Cells Ameliorates UVB-Induced Damage to Human Dermal Fibroblasts 

      Burón Aizpiri, María ORCID; Palomares Casado, Teodoro; Garrido Pascual, Patricia; Herrero de la Parte, Borja; García Alonso, Ignacio; Alonso Varona, Ana Isabel (MDPI, 2022-10-11)
      Human skin exposure to ultraviolet B (UVB) radiation can result in acute photodamage through oxidative modifications of cellular components and biomolecules involved in the metabolism of dermal cells. Recently, the therapeutic ...
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      Contributions of Women in Recent Research on Biopolymer Science 

      Veettil, Unnimaya Thalakkale; Olza, Sheila; Brugerolle de Fraissinette, Nelly; Bascans, Elodie; Castejón, Natalia; Adrien, Amandine; Fernández Marín, Rut; Nardin, Corinne; Fernandes, Susana C. M. (MDPI, 2022-03-30)
      Nowadays, biopolymers are playing a fundamental role in our society because of the environmental issues and concerns associated with synthetic polymers. The aim of this Special Issue entitled ‘Women in Polymer Science and ...
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      Cytocompatibility and Suitability of Protein-Based Biomaterials as Potential Candidates for Corneal Tissue Engineering 

      Romo Valera, Cristina; Guerrero Manso, Pedro Manuel ORCID; Arluzea de Jauregizar, Jon Andoni ORCID; Echevarría Ecenarro, Jesús ORCID; De la Caba Ciriza, María Coro ORCID; Andollo Victoriano, María Noelia ORCID (MDPI, 2021-03-31)
      The vision impairments suffered by millions of people worldwide and the shortage of corneal donors show the need of substitutes that mimic native tissue to promote cell growth and subsequent tissue regeneration. The current ...
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      Decreased expression of the β2 integrin on tumor cells is associated with a reduction in liver metastasis of colorectal cancer in mice 

      Benedicto García, Aitor; Márquez Clavijo, Joana ORCID; Herrero, Alba; Olaso Montero, Elvira; Kolaczkowska, Elzbieta; Arteta Ruiz, Beatriz ORCID (Biomed Central, 2017-12-06)
      Background: Lymphocyte Function-Associated Antigen-1 (LFA-1; CD18/CD11a) is one of the main adhesion molecules used by immune cells to infiltrate the liver under inflammatory conditions. Recently, the expression of this ...
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      Detection of Intratumor Heterogeneity in Modern Pathology: A Multisite Tumor Sampling Perspective 

      Cortés Díaz, Jesús María; De Petris, Giovanni; López, José I. (Frontiers Media, 2017-03-06)
      Current sampling protocols of neoplasms along the digestive tract and in the urinary bladder have to be updated, as they do not respond to the necessities of modern personalized medicine. We show here that an adapted version ...
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      Development and evaluation of different electroactive poly(vinylidene fluoride) architectures for endothelial cell culture 

      Durán Rey, David; Brito Pereira, Ricardo; Ribeiro, Clarisse; Ribeiro, Sylvie; Sánchez Margallo, Juan Alberto; Crisóstomo, Verónica; Irastorza Epelde, Igor ORCID; Silván, Unai; Lanceros Méndez, Senentxu; Sánchez Margallo, Francisco Miguel (Frontiers Media, 2022)
      Tissue engineering (TE) aims to develop structures that improve or even replace the biological functions of tissues and organs. Mechanical properties, physical-chemical characteristics, biocompatibility, and biological ...