Now showing items 1-3 of 3

    • Thumbnail

      Clinical management of the acute complications of sickle cell anemia: 11 years of experience in a tertiary hospital 

      Reparaz Goñi, Patricia; Serrano Pejenaute, Idoya; Adán Pedroso, Rosa; Astigarraga Aguirre, María Iciar; De Pedro Olabarri, Jimena; Echebarria Barona, Aizpea Beatriz; García Ariza, Miguel; López Almaraz, Ricardo; Del Orbe Barreto, Rafael Andrés; Vara Pampliega, Miriam; González Urdiales, Paula (Elsevier, 2022-07)
      Sickle cell disease is an emerging anemia in Europe leading to high morbidity with severe acute complications requiring hospital admission and chronic consequences. The management of these patients is complex and needs ...
    • Thumbnail

      Identification of germline cancer predisposition variants in pediatric sarcoma patients from somatic tumor testing 

      Alba Pavón, Piedad; Alaña, Lide; Gutiérrez Jimeno, Miriam; García Obregón, Susana; Imízcoz, Teresa; Panizo, Elena; González Urdiales, Paula; Echebarria Barona, Aizpea Beatriz; López Almaraz, Ricardo; Zaldumbide Dueñas, Laura; Astigarraga Aguirre, María Iciar; Patiño García, Ana; Villate, Olatz (Nature, 2023-02)
      Genetic predisposition is an important risk factor for cancer in children and adolescents but detailed associations of individual genetic mutations to childhood cancer are still under intense investigation. Among pediatric ...
    • Thumbnail

      Variants in vincristine pharmacodynamic genes involved in neurotoxicity at induction phase in the therapy of pediatric acute lymphoblastic leukemia 

      Martín Guerrero, Idoia; Gutiérrez Camino, Ángela ORCID; Echebarria Barona, Aizpea Beatriz; Astigarraga Aguirre, María Iciar; García de Andoin Barandiaran, Nagore; Navajas Gutiérrez, Aurora; García-Orad Carles, África (Springer, 2019-02-06)
      Vincristine is an important drug of acute lymphoblastic leukemia (ALL) treatment protocols that can cause neurotoxicity. Patients treated with LAL/SHOP protocols often suffer from vincristine-related neurotoxicity in early ...