Browsing Artículos by Author "Haertle, Larissa"

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      Actin cytoskeleton deregulation confers midostaurin resistance in FLT3-mutant acute myeloid leukemia 

      Garitano Trojaola, Andoni; Sancho Erkizia, Ana ORCID; Götz, Ralph; Eiring, Patrick; Walz, Susanne; Jetani, Hardikkumar; Gil-Pulido, Jesús; Da Via, Matteo Claudio; Teufel, Eva; Rhodes, Nadine; Haertle, Larissa; Arellano-Viera, Estibaliz; Tibes, Raoul; Rosenwald, Andreas; Rasche, Leo; Hudecek, Michael; Sauer, Markus; Groll, Jürgen; Einsele, Hermann; Kraus, Sabrina; Kortüm, Martin K. (Nature Research, 2021-06-25)
      The presence of FMS-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) is one of the most frequent mutations in acute myeloid leukemia (AML) and is associated with an unfavorable prognosis. FLT3 inhibitors, ...