Now showing items 1-20 of 31

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      Antibacterial and antifungal activity of the human endometrial fluid during the natural cycle 

      Bregón Villahoz, Marta; Moragues Tosantos, María Dolores; Arrieta Aguirre, Inés; Azkargorta, Mikel; Laínz, Lucía; Diez Zapirain, Miren; Iglesias Calabria, María; Prieto Molano, María Begoña; Matorras, Ana; Expósito Navarro, María Antonia; Elortza, Felix; Matorras Weinig, José Roberto (Hindawi, 2021-06-16)
      [EN] Purpose. Some microbiota patterns have been associated with favorable IVF prognosis and others with pathological conditions. The endometrial fluid aspirate (EFA) contains antibacterial proteins that are enriched in ...
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      Collision tumour involving a rectal gastrointestinal stromal tumour with invasion of the prostate and a prostatic adenocarcinoma 

      Macías García, Laura; De la Hoz Herazo, Haydee; Robles Frías, Antonio; Pareja Megía, María J.; López Garrido, Juan; López Fernández de Villaverde, José Ignacio (BioMed Central, 2012)
      Background: Gastrointestinal stromal tumours (GISTs) are the most common primary mesenchymal neoplasia in the gastrointestinal tract, although they represent only a small fraction of total gastrointestinal malignancies ...
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      Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal 

      Turajlic, Samra; Xu, Hang; Litchfield, Kevin; Rowan, Andrew; Horswell, Stuart; Chambers, Tim; O'Brien, Tim; López Fernández de Villaverde, José Ignacio; Watkins, Thomas B. K.; Nicol, David; Stares, Mark; Challacombe, Ben; Hazell, Steve; Chandra, Ashish; Mitchell, Thomas J.; Au, Lewis; Eichler-Jonsson, Claudia; Jabbar, Faiz; Soultati, Aspasia; Chowdhury, Simon; Rudman, Sarah; Lynch, Joanna; Archana Sinduri, Fernando; Stamp, Gordon; Nye, Emma; Stewart, Aengus; Xing, Wei; Smith, Jonathan C.; Escudero, Mickael; Huffman, Adam; Matthews, Nik; Elgar, Greg; Phillimore, Ben; Costa, Marta; Begum, Sharmin; Ward, Sophia; Salm, Max; Boeing, Stefan; Fisher, Rosalie; Spain, Lavinia; Navas, Carolina; Gronroos, Eva; Hobor, Sebastijan; Sharma, Sarkhara; Aurangzeb, Ismaeel; Lall, Sharanpreet; Polson, Alexander; Varia, Mary; Horsfield, Catherine; Fotiadis, Nicos; Pickering, Lisa; Schwarz, Roland F.; Silva, Bruno; Herrero, Javier; Luscombe, Nick M.; Jamal-Hanjani, Mariam; Rosenthal, Rachel; Birkbak, Nicolai J.; Wilson, Gareth A.; Pipek, Orsolya; Ribli, Dezso; Krzystanek, Marcin; Csabai, Istvan; Szállási, Zoltán; Gore, Martin E.; McGranahan, Nicholas; Van Loo, Peter; Campbell, Peter; Larkin, James; Swanton, Charles (Cell Press, 2018-04-19)
      The evolutionary features of clear-cell renal cell carcinoma (ccRCC) have not been systematically studied to date. We analyzed 1,206 primary tumor regions from 101 patients recruited into the multi-center prospective study, ...
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      Dipeptidyl-Peptidase IV Activity Is Correlated with Colorectal Cancer Prognosis 

      Larrinaga Embeita, Gorka; Pérez Urzelai, Itxaro; Sanz Echevarría, María Begoña; Beitia San Vicente, Maider; Errarte Yarza, Peio; Fernández Atucha, Ainhoa; Blanco Criado, Lorena; Etxezarraga Zuluaga, María Carmen; Gil Goicouría, Francisco Javier; López Fernández de Villaverde, José Ignacio (Public Library Science, 2015-03-19)
      Background Dipeptidyl-peptidase IV (EC 3.4.14.5) (DPPIV) is a serine peptidase involved in cell differentiation, adhesion, immune modulation and apoptosis, functions that control neoplastic transformation. Previous ...
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      Dual-Specificity Phosphatases in Neuroblastoma Cell Growth and Differentiation 

      Nunes Xavier, Caroline E.; Zaldumbide Dueñas, Laura; Aurtenetxe, Olaia; López Almaraz, Ricardo; López Fernández de Villaverde, José Ignacio; Pulido Murillo, Rafael (MDPI, 2019-03-01)
      Dual-specificity phosphatases (DUSPs) are important regulators of neuronal cell growth and differentiation by targeting proteins essential to neuronal survival in signaling pathways, among which the MAP kinases (MAPKs) ...
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      Effect of vitamin E administered to men in infertile couples on sperm and assisted reproduction outcomes: a double-blind randomized study 

      Matorras Weinig, José Roberto; Pérez Sanz, Jairo; Corcóstegui, Beatriz; Pérez Ruiz, Irantzu; Malaina Celada, Iker; Quevedo, Sara María; Aspichueta Vivanco, Fermín; Crisol, Lorena; Martinez Indart, Lorea; Prieto Molano, María Begoña; Expósito Navarro, María Antonia (Elsevier, 2020-12)
      Objective: To evaluate the influence on sperm parameters and invitro fertilization (IVF) outcomes of the administration of 400 mg/day of vitamin E for 3 months to men from infertile couples who are undergoing IVF. Design: ...
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      Estimation of preterm labor immediacy by nonlinear methods 

      Malaina Celada, Iker; Martínez Fernández, Luis; Matorras Weinig, José Roberto; Bringas Roldán, Carlos; Aranburu Laka, Larraitz; Fernández-Llebrez del Rey, Luis; González, Leire; Arana, Itziar; Pérez Pinilla, Martín Blas; Martínez de la Fuente Martínez, Ildefonso Abel (Public Library Science, 2017-06-01)
      Preterm delivery affects about one tenth of human births and is associated with an increased perinatal morbimortality as well as with remarkable costs. Even if there are a number of predictors and markers of preterm delivery, ...
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      Food groups, diet quality and colorectal cancer risk in the Basque Country 

      Alegría Lertxundi, Iker; Aguirre Gómez, Carmelo; Bujanda Fernández de Pierola, Luis; Fernández Pablos, Francisco Javier; Polo, Francisco; Ordovás, José María; Etxezarraga Zuluaga, María Carmen; Zabalza Estévez, Ignacio; Larzabal, Mikel; Portillo Villares, María Isabel; Martínez de Pancorbo Gómez, María de los Angeles; García Etxebarria, Koldo; Rocandio Pablo, Ana María; Arroyo Izaga, Marta (Baishideng Publishing Group Inc, 2020-07-28)
      BACKGROUND The results obtained to date concerning food groups, diet quality and colorectal cancer (CRC) risk vary according to criteria used and the study populations. AIM To study the relationships between food groups, ...
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      Gene Expression Study and Pathway Analysis of Histological Subtypes of Intestinal Metaplasia that Progress to Gastric Cancer 

      Companioni, Osmel; Sanz Anquela, José Miguel; Pardo López, María Luisa; Puigdecanet Riubugent, Eulàlia; Nonell Mazelón, Lara; García, Nadia; Parra Blanco, Verónica; López, Consuelo; Andreu, Victoria; Cuatrecasas, Miriam; Garmendia Irizar, Maddi; Gisbert, Javier P.; González, Carlos A.; Sala, Núria (Public Library Science, 2017-04-25)
      Background Intestinal metaplasia (IM) is a precursor lesion that precedes gastric cancer (GC). There are two IM histological subtypes, complete (CIM) and incomplete (IIM), the latter having higher progression rates to ...
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      Gene–Diet Interactions in Colorectal Cancer: Survey Design, Instruments, Participants and Descriptive Data of a Case–Control Study in the Basque Country 

      Alegría Lertxundi, Iker; Aguirre Gómez, Carmelo; Bujanda Fernández de Pierola, Luis; Fernández Pablos, Francisco Javier; Polo, Francisco; Ordovás, José María; Etxezarraga Zuluaga, María Carmen; Zabalza Estévez, Ignacio; Larzabal, Mikel; Portillo Villares, María Isabel; Martínez de Pancorbo Gómez, María de los Angeles; Palencia Madrid, Leire; García Etxebarria, Koldo; Rocandio Pablo, Ana María; Arroyo Izaga, Marta (MDPI, 2020)
      Epidemiologic studies have revealed inconsistent evidence of gene-diet interaction in relation to colorectal cancer (CRC). The aim of this study was to analyze them in a sample of cases and controls from the population-based ...
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      Human Papillomavirus (HPV) genotype 18 variants in patients with clinical manifestations of HPV related infections in Bilbao, Spain 

      Arroyo, Sara L.; Basaras Ibarzabal, Miren; Arrese Arratibel, Miren Elixabete; Hernáez, Silvia; Andia Ortiz, Daniel; Esteban, Valetín; García Etxebarria, Koldo; Jugo Orrantia, Begoña Marina; Cisterna Cáncer, Ramón (BioMed Central, 2012)
      Background:Human papillomavirus (HPV) variants differ in their biological and chemical properties, and therefore, may present differences in pathogenicity. Most authors classified variants based on the phylogenetic analysis ...
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      Liver osteopontin is required to prevent the progression of age-related nonalcoholic fatty liver disease 

      Gómez Santos, Beatriz; Saenz de Urturi Indart, Diego; Nuñez García, Maitane; González Romero, Francisco; Buqué García, Xabier; Aurrekoetxea Galindo, Igor; Gutiérrez de Juan, Virginia; González Rellán, María Jesús; García Monzón, Carmelo; González Rodríguez, Águeda; Mosteiro González, Lorena; Errazti Olartecoechea, Gaizka; Mifsut Porcel, Patricia; Gaztambide Sáenz, María Sonia; Castaño González, Luis Antonio; Martín Plágaro, César Augusto; Nogueiras Pozo, Rubén; Martínez Chantar, María Luz; Syn, Wing-Kin; Aspichueta Celaá, Patricia (Wiley, 2020-07-07)
      [EN] Osteopontin (OPN), a senescence-associated secretory phenotype factor, is increased in patients with nonalcoholic fatty liver disease (NAFLD). Cellular senescence has been associated with age-dependent hepatosteatosis. ...
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      Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness 

      Ruiz de Garibay, Gorka; Herranz, Carmen; Llorente, Alicia; Boni, Jacopo; Serra- Musach, Jordi; Mateo, Francesca; Aguilar, Helena; Gómez-Baldó, Laia; Petit, Anna; Vidal, August; Climent, Fina; Hernández-Losa, Javier; Cordero, Álex; González- Suárez, Eva; Sánchez-Mut, José Vicente; Esteller, Manel; Llatjós, Roger; Varela, Mar; López Fernández de Villaverde, José Ignacio; García, Nadia; Extremera, Ana I.; Gumà, Anna; Ortega, Raúl; Plà, María Jesús; Fernández, Adela; Pernas, Sònia; Falo, Catalina; Morilla, Idoia; Campos, Miriam; Gil, Miguel; Román, Antonio; Molina-Molina, María; Ussetti, Piedad; Laporta, Rosalía; Valenzuela, Claudia; Ancochea, Julio; Xaubet, Antoni; Casanova, Álvaro; Pujana, Miguel Angel (Public Library Science, 2015-07-07)
      Lymphangioleiomyomatosis (LAM) is a rare lung-metastasizing neoplasm caused by the proliferation of smooth muscle-like cells that commonly carry loss-of-function mutations in either the tuberous sclerosis complex 1 or 2 ...
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      Meta-Analysis of the Embryo Freezing Transfer Interval 

      Matorras Weinig, José Roberto; Pijoán, José Ignacio; Pérez Ruiz, Irantzu; Laínz, Lucía; Malaina Celada, Iker; Borjaba Asensio, Sonia (Wiley, 2021-04)
      Background The decision of whether frozen embryo transfer (FET) should be performed in the cycle immediately after OPU or at least one cycle later is controversial. FET could improve pregnancy rates in IVF; however, how ...
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      Micrornas Expression Profile in Solid and Unicystic Ameloblastomas 

      Setién Olarra, Amaia; Marichalar Mendia, Xabier; García Bediaga, Naiara; Aguirre Echebarria, Pablo; Aguirre Urizar, José Manuel; Mosqueda Taylor, Adalberto (Public Library Science, 2017-10-20)
      Objectives Odontogenic tumors (OT) represent a specific pathological category that includes some lesions with unpredictable biological behavior. Although most of these lesions are benign, some, such as the ameloblastoma, ...
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      (Pro)renin Receptor Expression Increases throughout the Colorectal Adenoma-Adenocarcinoma Sequence and It Is Associated with Worse Colorectal Cancer Prognosis 

      Beitia San Vicente, Maider; Solano Iturri, Jon Danel; Errarte Yarza, Peio; Calvete Candenas, Julio; Loizate Totoricagüena, Alberto; Etxezarraga Zuluaga, María Carmen; Sanz Echevarría, María Begoña; Larrinaga Embeita, Gorka (MDPI, 2019-06-24)
      (Pro)renin receptor (PRR) is a protein that takes part in several signaling pathways such as Renin Angiotensin System and Wnt signalling. Its biological role has recently been related to cancer progression and in this ...
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      Protein tyrosine phosphatase modulates cell growth and associates with poor outcome in human neuroblastoma 

      Nunes Xavier, Caroline E.; Aurtenetxe, Olaia; Zaldumbide Dueñas, Laura; López Almaraz, Ricardo; Erramuzpe Aliaga, Asier; Cortés Díaz, Jesús María; López Fernández de Villaverde, José Ignacio; Pulido Murillo, Rafael (BMC, 2019-12-14)
      Background Protein tyrosine phosphatases (PTPs) regulate neuronal differentiation and survival, but their expression patterns and functions in human neuroblastoma (NB) are scarcely known. Here, we have investigated the ...
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      Sea Bass Primary Cultures versus RTgill-W1 Cell Line: Influence of Cell Model on the Sensitivity to Nanoparticles 

      Jimeno Romero, Alba; Gwinner, Frederik; Müller, Michelle; Mariussen, Espen; Soto López, Manuel; Kohl, Yvonne (MDPI, 2021-11-20)
      Determination of acute toxicity to vertebrates in aquatic environments is mainly performed following OECD test guideline 203, requiring the use of a large number of fish and with mortality as endpoint. This test is also ...
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      Self-Organization and Information Processing: from Basic Enzymatic Activities to Complex Adaptive Cellular Behavior 

      Martínez de la Fuente Martínez, Ildefonso Abel; Martínez Fernández, Luis; Carrasco Pujante, José; Fedetz, María; López Fernández de Villaverde, José Ignacio; Malaina Celada, Iker (Frontiers Media, 2021-05-21)
      One of the main aims of current biology is to understand the origin of the molecular organization that underlies the complex dynamic architecture of cellular life. Here, we present an overview of the main sources of ...
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      Serotonin 5-HT2A receptor expression and functionality in postmortem frontal cortex of subjects with schizophrenia: Selective biased agonism via Gαi1-proteins 

      García Bea, Aintzane; Miranda Azpiazu, Patricia; Muguruza Millán, Carolina; Marmolejo Martínez-Arteseroa, Sara; Díez Alarcia, Rebeca; Gabilondo Urquijo, Ane Miren; Callado Hernando, Luis Felipe; Morentin Campillo, Benito; González Maeso, Javier; Meana Martínez, José Javier (Elsevier, 2019-12)
      Serotonin 5-HT2A receptors (5-HT(2A)Rs) have been implicated in schizophrenia. However, postmortem studies on 5-HT(2A)Rs expression and functionality in schizophrenia are scarce. The 5-HT2AR mRNA and immunoreactive protein ...