Browsing Artículos by Author "Xirodimas, Dimitri"

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      Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via DEPTOR-mTOR axis 

      Serrano Maciá, Marina; Simon, Jorge; González Rellán, María Jesús; Azkargorta, Mikel; Goikoetxea Usandizaga, Naroa; Lopitz Otsoa, Fernando; Saenz de Urturi Indart, Diego; Rodríguez Agudo, Rubén; Lachiondo Ortega, Sofía; Mercado Gómez, María; Gutiérrez de Juan, Virginia; Bizkarguenaga, Maider; Fernández Ramos, David; Buqué García, Xabier ORCID; Baselli, Guido A.; Valenti, Luca; Iruzubieta, Paula; Crespo, Javier; Villa, Erica; Bañales Asurmendi, Jesús María ORCID; Ávila, Matías A. ORCID; Marin, José J. G.; Aspichueta Celaá, Patricia; Sutherland, James D.; Barrio Olano, María Rosa; Mayor Martínez, Ugo ORCID; Elortza, Felix; Xirodimas, Dimitri; Nogueiras Pozo, Rubén; Delgado, Teresa C.; Martínez Chantar, María Luz ORCID (Elsevier, 2021-06-18)
      [EN] Objective: Neddylation is a druggable and reversible ubiquitin-like post-translational modification upregulated in many diseases, including liver fibrosis, hepatocellular carcinoma, and more recently, non-alcoholic ...