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Role of Monoubiquitylation on the Control of IκBα Degradation and NF-κB Activity 

Da Silva-Ferrada, Elisa; Torres-Ramos, Mónica; Aillet, Fabienne; Campagna, Michela; Matute Almau, Carlos José; Rivas, Carmen; Rodríguez Medina, Manuel Salvador (Public Library of Science, 2011-10-12)
The NF-κB pathway is regulated by multiple post-translational modifications including phosphorylation, ubiquitylation and SUMOylation. Many of these modifications act on the natural inhibitor IκBα modulating its capacity ...
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Interactome of the Autoimmune Risk Protein ANKRD55 

Ugidos Damboriena, Nerea; Mena Lucía, Jorge; Baquero, Sara; Alloza Moral, Iraide; Azkargorta, Mikel; Elortza, Felix; Vandenbroeck, Koen (Frontiers Media, 2019-09-18)
The ankyrin repeat domain-55 (ANKRD55) gene contains intronic single nucleotide polymorphisms (SNPs) associated with risk to contract multiple sclerosis, rheumatoid arthritis or other autoimmune disorders. Risk alleles of ...
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Exome sequencing in multiple sclerosis families identifies 12 candidate genes and nominates biological pathways for the genesis of disease 

Vilariño Güell, Carles; Zimprich, Alexander; Martinelli Boneschi, Filippo; Herculano, Bruno; Wang, Zhe; Matesanz, Fuencisla; Urcelay, Elena; Vandenbroeck, Koen; Leyva, Laura; Gris, Denis; Massaad, Charbel; Quandt, Jacqueline A.; Traboulsee, Anthony L.; Encarnacion, Mary; Bernales, Cecily Q.; Follett, Jordan; Yee, Irene M.; Criscuoli, Maria G.; Deutschlander, Angela; Reinthaler, Eva M.; Zrzavy, Tobias; Mascia, Elisabetta; Zauli, Andrea; Esposito, Federica; Alcina, Antonio; Izquierdo, Guillermo; Espino Paisan, Laura; Mena Lucía, Jorge; Rodríguez-Antigüedad Zarranz, Alfredo; Urbaneja Romero, Patricia; Ortega Pinazo, Jesús; Song, Weihong; Sadovnick, A. Dessa (Public Library Science 15(6) : (2019) // Article ID e1008180, 2019-06-06)
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system characterized by myelin loss and neuronal dysfunction. Although the majority of patients do not present familial aggregation, Mendelian forms ...
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Patient-Specific iPSC-Derived Cellular Models of LGMDR1 

Mateos Aierdi, Alba Judith; Dehesa Etxebeste, Martxel Pedro; Goicoechea Bianchi, María; Aiastui, Ana; Richaud-Patin, Yvonne; Jiménez Delgado‬, Senda; Raya, Ángel; Naldaiz Gastesi, Neia; López de Munain Arregui, Adolfo José (Elsevier, 2021-04-08)
Limb-girdle muscular dystrophy recessive 1 (LGMDR1) represents one of the most common types of LGMD in the population, where patients develop a progressive muscle degeneration. The disease is caused by mutations in calpain ...

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AuthorMena Lucía, Jorge (2)Vandenbroeck, Koen (2)Aiastui, Ana (1)Aillet, Fabienne (1)... View MoreDepartamento (cas.)
Bioquímica y biología molecular (4)
Neurociencias (4)Departamento (eus.)Biokimika eta biologia molekularra (4)
Neurozientziak (4)
SubjectAGRICULTURAL AND BIOLOGICAL SCIENCES (1)BIOCHEMISTRY AND MOLECULAR BIOLOGY (1)MEDICINE (1)... View MoreDate Issued2021 (1)2019 (2)2011 (1)Language(ISO)eng (4)

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