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Novel Population Pharmacokinetic Model for Linezolid in Critically Ill Patients and Evaluation of the Adequacy of the Current Dosing Recommendation
(MDPI, 2020-01-09)
Antimicrobial treatment in critically ill patients remains challenging. The aim of this study
was to develop a population pharmacokinetic model for linezolid in critically ill patients and to
evaluate the adequacy of ...
Novel advances in the design of three-dimensional bio-scaffolds to control cell fate: translation from 2D to 3D
(Elsevier, 2012-05-07)
Recreating the most critical aspects of the native extracellular matrix (ECM) is fundamental to understand and control the processes regulating cell fate and cell function. From the ill-defined complexity to the controlled ...
Has the adipokine profile an influence on the catch-up growth type in small for gestational age infants?
(Springer, 2019-06-17)
[EN] Infants born small for gestational age (SGA) are at increased risk of perinatal morbidity, persistent short stature, and metabolic alterations in later life. Moreover, the post-natal growth pattern of SGA infants may ...
On-campus food environment in two European public universities: food purchasing behaviours ,choice determinants and opinions on the food availability among the university community
(2022-02-16)
To date, there are no studies on the food environment (FE) in European universities, that include both external and personal domains. This cross-sectional observational study was designed to assess the FE through both ...
Optimization of 100 µm alginate-poly-L-lysine-alginate capsules for intravitreous administration
(Elsevier, 2011-09-24)
The field of cell microencapsulation is advancing rapidly. Particle size plays a critical role in terms of biocompatibility and limits decisively its applicability. Producing reduced size microcapsules involves broadening ...
Omega‐3 LCPUFA supplement: a nutritional strategy to prevent maternal and neonatal oxidative stress
(Wiley, 2016-04-13)
There is controversy about fish‐oil supplementation and oxidative damage. This ambiguity should be explored to elucidate its role as modulator of oxidative stress, especially during gestation and postnatal life. This is ...
The synergistic effects of the RGD density and the microenvironment on the behavior of encapsulated cells: In vitro and in vivo direct comparative study
(John Wiley & Sons, 2014-11)
The inclusion of the tripeptide RGD (Arg-Gly-Asp) in otherwise inert biomaterials employed for cell encapsulation has been observed to be an effective strategy to provide the immobilized cells with a more suitable ...
Design and evaluation of nucleic-acid based medicinal products to address corneal inflammation by gene therapy
(2022-03-04)
La suplementación génica consiste en la administración de ácidos nucleicos (ADN o ARNm) para inducir la producción de una proteína terapéutica. En la actualidad, el uso del ARNm se ha extendido debido su alta eficacia, ...
Resistencia a antibióticos en dos Unidades de Medicina Intensiva de un hospital terciario: efecto de la descontaminación digestiva selectiva.
(2023-01-27)
La descontaminación digestiva selectiva (DDS) es una estrategia profiláctica basada en la administración de antibióticos tópicos no absorbibles en la mucosa oral y en el tracto gastrointestinal y de un antibiótico de amplio ...
Mapping the concept of health care integration: A lexicographic analysis of scientific literature
(Elsevier, 2024-05)
Background
Systems fragmentation is a major challenge for an efficient organization, integration being a potential solution also proposed in health care field, including pharmacy as a player. However, the use of different ...