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Modular magnetite-filled nanomicelles for multimodal imaging-guided development of effective anticancer vaccines
(2017-09-08)
Tanto las células cancerosas como muchos de los patógenos que causan enfermedades crónicas han desarrollado mecanismos para evadir al sistema inmune. Por lo tanto, es necesario desarrollar nuevas tecnologías que nos permitan ...
Valoración diagnóstica y pronóstica de la citología oral en la enfermedad periimplantaria
(2017-07-19)
INTRODUCCIÓN:La rehabilitación de pacientes mediante implantes dentales es un método predecible, pero no exento de complicaciones. Diferentes técnicas clínicas (profundidad y sangrado al sondaje) y radiográficas, se aceptan ...
The 2018 biomembrane curvature and remodeling roadmap
(IOP Publishing, 2018-08-30)
The importance of curvature as a structural feature of biological membranes has been recognized for many years and has fascinated scientists from a wide range of different backgrounds. On the one hand, changes in membrane ...
Transcriptional control of prostate cancer metabolism
(2017-12-18)
La transformación y la progresión tumoral van acompañados de cambios metabólicos. Los principales co-reguladores metabólicos son capaces de orquestar la modulación de múltiples rutas metabólicas a través de la regulación ...
Mapeo por asociación mediante genes candidatos en Palmera de Aceite Africana (E. guineensis Jacq.)
(2017-04-07)
Actualmente, la palmera de aceite africana (E.guineensis Jacq.) es el mayor cultivooleaginoso en cuanto a producción y rendimiento. El proceso de mejora tradicional presentalimitaciones como los largos ciclos de selección ...
Selective Interaction of Syntaxin 1A with KCNQ2: Possible Implications for Specific Modulation of Presynaptic Activity
Regev, Noa; Degani-Katzav, Nurit; Korngreen, Alon; Etzioni, Adi; Siloni, Sivan; Alaimo Campi, Alessandro 
; Chikvashvili, Dodo; Villarroel Muñoz, Álvaro; Attali, Bernard; Lotan, Ilana (Public Library Science,, 2009-08-13)
; Chikvashvili, Dodo; Villarroel Muñoz, Álvaro; Attali, Bernard; Lotan, Ilana (Public Library Science,, 2009-08-13)
KCNQ2/KCNQ3 channels are the molecular correlates of the neuronal M-channels, which play a major role in the control of neuronal excitability. Notably, they differ from homomeric KCNQ2 channels in their distribution pattern ...
Highlights of the 2nd International Symposium on Tribbles and Diseases: Tribbles Tremble in Therapeutics for Immunity, Metabolism, Fundamental Cell Biology and Cancer
Cui, Bing; Eyers, Patrick A.; Dobens, Leonard L.; Tan, Nguan Soon; Mace, Peter D.; Link, Wolfgang A.; Kiss Toth, Endre; Keeshan, Karen; Nakamura, Takuro; Pear, Warren S.; Feseha, Yodit; Johnston, Jessica; Carracedo Pérez, Arkaitz ; Scheideler, Marcel; llyas, Zabran; Bauer, Robert C.; Erusalimsky, Jorge D.; Grzesik, Dominika; Salamanca Viloria, Juan; Lv, Xiaoxi; Jin, Yishi; Li, Ke; Velasco, Guillermo; Shang, Shuang; Lizcano de Vega, José Miguel; Zhang, Xiaowei; Zhou, Jichao; Yu, Jiaojiao; Hua, Fang; Wang, Feng; Liu, Shanshan; Yu, Jinmei; Hu, Zhuowei (Institute of Materia Medica, 2019-03)
; Scheideler, Marcel; llyas, Zabran; Bauer, Robert C.; Erusalimsky, Jorge D.; Grzesik, Dominika; Salamanca Viloria, Juan; Lv, Xiaoxi; Jin, Yishi; Li, Ke; Velasco, Guillermo; Shang, Shuang; Lizcano de Vega, José Miguel; Zhang, Xiaowei; Zhou, Jichao; Yu, Jiaojiao; Hua, Fang; Wang, Feng; Liu, Shanshan; Yu, Jinmei; Hu, Zhuowei (Institute of Materia Medica, 2019-03)
The Tribbles (TRIB) family of pseudokinase proteins has been shown to play key roles in cell cycle, metabolic diseases, chronic inflammatory disease, and cancer development. A better understanding of the mechanisms of TRIB ...
Application of Solid Lipid Nanoparticles to Improve the Efficiency of Anticancer Drugs
Bayón Cordero, Laura; ; Arana Urbieta, Lide (MDPI, 2019-03-22)
(MDPI, 2019-03-22)
Drug delivery systems have opened new avenues to improve the therapeutic effects of already-efficient molecules. Particularly, Solid Lipid Nanoparticles (SLNs) have emerged as promising nanocarriers in cancer therapy. SLNs ...
Solid Lipid Nanoparticles Surface Modification Modulates Cell Internalization and Improves Chemotoxic Treatment in an Oral Carcinoma Cell Line
Arana Urbieta, Lide ; Bayón Cordero, Laura; Sarasola Telleria, Laura Isabel; Berasategi, Miren; Ruiz, Sandra; (MDPI, 2019-03-20)
; Bayón Cordero, Laura; Sarasola Telleria, Laura Isabel; Berasategi, Miren; Ruiz, Sandra; (MDPI, 2019-03-20)
Solid lipid nanoparticles (SLN) present low toxicity, versatility to incorporate both lipophilic and hydrophilic drugs, controlled drug release and they are easy to scale-up. It is well known that the endocytosis pathway ...
In-Depth Proteomic Characterization of Classical and Non-Classical Monocyte Subsets
Segura, Victor; Valero, M. Luz; Cantero, Laura; Muñoz, Javier; Zarzuela, Eduardo; García, Fernando; Aloria Escolastico, Kerman; Beaskoetxea Lejarzegi, Javier; Arizmendi Bastarrika, Jesús María ; Navajas, Rosana; Paradela, Alberto; Díez, Paula; Degano, Rosa M.; Fuentes, Manuel; Orfao, Alberto; García Montero, Andrés; Garin-Muga, Alba; Corrales, Fernando J.; Sánchez del Pino, Manuel M. (MDPI, 2018-02-05)
; Navajas, Rosana; Paradela, Alberto; Díez, Paula; Degano, Rosa M.; Fuentes, Manuel; Orfao, Alberto; García Montero, Andrés; Garin-Muga, Alba; Corrales, Fernando J.; Sánchez del Pino, Manuel M. (MDPI, 2018-02-05)
Monocytes are bone marrow-derived leukocytes that are part of the innate immune system. Monocytes are divided into three subsets: classical, intermediate and non-classical, which can be differentiated by their expression ...