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Now showing items 11241-11250 of 12452
Candida albicans increases the aerobic glycolysis and activates MAPK–dependent inflammatory response of liver sinusoidal endothelial cells
(Elsevier, 2024-05)
The liver, and more specifically, the liver sinusoidal endothelial cells, constitute the beginning of one of the most important responses for the elimination of hematogenously disseminated Candida albicans. Therefore, we ...
Identification of the Most Immunoreactive Antigens of Candida auris to IgGs from Systemic Infections in Mice
(ACS, 2024-04)
The delay in making a correct diagnosis of Candida auris causes concern in the healthcare system setting, and immunoproteomics studies are important to identify immunoreactive proteins for new diagnostic strategies. In ...
On the parallelization of multipacting simulation codes for the design of particle accelerator components
(Springer Nature, 2024)
Particle trajectory and collision simulation is a critical step of the design and con-
struction of novel particle accelerator components. However it requires a huge
computational effort which can slow down the design ...
Enantiopure [6]-Azairidahelicene by Dynamic Kinetic Resolution of a Configurationally Labile [4]-Helicene
(Wiley, 2024-06)
A pair of enantiopure [6]-azairidahelicenes incorporating chirality at the metal center and on the helicenic ligand were synthesized by dynamic kinetic resolution (dkr) of a configurationally labile [4]-helicenic ligand ...
Materials and Strategies to Enhance Melt Electrowriting Potential
(Wiley, 2024-06)
Melt electrowriting (MEW) is an emerging additive manufacturing (AM) technology that enables the precise deposition of continuous polymeric microfibers, allowing for the creation of high-resolution constructs. In recent ...
Cholesterol-dependent membrane fusion induced by the gp41 membrane-proximal external region-transmembrane domain connection suggests a mechanism for broad HIV-1 neutralization
(ASM, 2014)
The HIV-1 glycoprotein 41 promotes fusion of the viral membrane with that of the target cell. Structural, biochemical, and biophysical studies suggest that its membrane-proximal external region (MPER) may interact with the ...
Electrical features of the diabetic myocardium. Arrhythmic and cardiovascular Safety considerations in diabetes
(Frontiers Media, 2021-07-08)
[EN] Diabetes is a chronic metabolic disease characterized by hyperglycemia in the absence
of treatment. Among the diabetes-associated complications, cardiovascular disease is
the major cause of mortality and morbidity ...
Conformational Plasticity Underlies Membrane Fusion Induced by an HIV Sequence Juxtaposed to the Lipid Envelope
(Springer Nature, 2021-01-14)
Envelope glycoproteins from genetically-divergent virus families comprise fusion peptides (FPs) that have been posited to insert and perturb the membranes of target cells upon activation of the virus-cell fusion reaction. ...
Conjugated linoleic acid metabolite impact in colorectal cancer: a potential microbiome-based precision nutrition approach
(Oxford University Press, 2024-05-10)
Colorectal cancer (CRC) is the second most deadly and the third most diagnosed cancer in both sexes worldwide. CRC pathogenesis is associated with risk factors such as genetics, alcohol, smoking, sedentariness, obesity, ...
Neologismos en la ciencia política. Analizando el concepto de partido desafiante.
(Asociación Vasca de Sociología y Ciencia Política, 2024-07-05)
Los partidos son actores políticos complejos y cambiantes que han ido adaptando sus estructuras organizativas y sus estrategias en función del contexto en el que operan. Debido a la necesidad de comprender la evolución de ...