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Now showing items 9921-9930 of 10574
High Mitochondrial DNA Stability in B-Cell Chronic Lymphocytic Leukemia
(Public Library Science, 2009-11-18)
Background: Chronic Lymphocytic Leukemia (CLL) leads to progressive accumulation of lymphocytes in the blood, bone marrow, and lymphatic tissues. Previous findings have suggested that the mtDNA could play an important role ...
Systematic Review of the Potential of MicroRNAs in Diffuse Large B Cell Lymphoma
(MDPI, 2019-01-26)
Diffuse large B cell lymphoma (DLBCL) is the most common subtype of invasive non-Hodgkin's lymphoma (NHL). DLBCL presents with variable backgrounds, which results in heterogeneous outcomes among patients. Although new tools ...
MTHFR Polymorphisms In Childhood Acute lymphoblastic Leukemia: Influence On Methotrexate Therapy
(Dove Medical Press LTD, 2017)
Methotrexate (MTX) is an important component in the therapy used to treat childhood
acute lymphoblastic leukemia (ALL). Methylenetetrahydrofolate reductase (MTHFR) is a key
enzyme for MTX pharmacokinetics. Two single-nucleotide ...
Confirmation of involvement of new variants at CDKN2A/B in pediatric acute lymphoblastic leukemia susceptibility in the Spanish population
(Public Library Science, 2017-05-08)
The locus CDKN2A/B (9p21.3), which comprises the tumor suppressors genes CDKN2A and CDKN2B and the long noncoding RNA (lncRNA) known as ANRIL (or CDKN2B-AS), was associated with childhood acute lymphoblastic leukemia (ALL) ...
Involvement of SNPs in miR-3117 and miR-3689d2 in Childhood Acute Lymphoblastic Leukemia Risk
(Board, 2018-04-01)
Acute lymphoblastic leukemia (ALL) is the most common cancer in children. Numerous studies have shown that microRNAs (miRNAs) could play a role in this disease. Nowadays, more than 2500 miRNAs have been described, that ...
Synthesis of advanced bio-based green materials from renewable biopolymers
(Elsevier, 2021-01-30)
Polymeric materials such as hydrogels have become necessary in our daily lives. Hydrogels are three-dimensionally cross-linked polymeric networks that can absorb large amounts of water. Thanks to their properties, hydrogels ...
Synthesis and characterization of epoxy polymers containing azobenzene groups that exhibit optical birefringence
(2007-12-03)
A push–pull azo dye (DO3) was used as photosensitive substance to satisfactorily synthesize new epoxy polymers containing azo groups covalently linked. Three different amines BA, TA and MXDA were used as hardeners. Materials ...
Sistema literario vasco en el año 2020: recuperándose del covid-19
(2021-04)
Este artículo trata de revisar lo ofrecido por la literatura vasca durante el año 2020 en términos de sistema. Así, reseña los acontecimientos más relevantes del ámbito, así como los estragos que ha podido causar la crisis ...
El uso de juegos de Rol en la docencia: el juego de la Negociación Climática Internacional
(2015-05-14)
En este artículo presentamos un juego de rol sobre negociación climática internacional que ha sido diseñado por los autores. El juego ha sido utilizado tanto en la universidad, con alumnos que están cursando los mismos ...