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Graphene Oxide–Silver Nanoparticle Nanohybrids: Synthesis, Characterization, and Antimicrobial Properties
dc.contributor.author | Cobos Zamarreño, Mónica | |
dc.contributor.author | De la Pinta Aresti, Iker | |
dc.contributor.author | Quindós Andrés, Guillermo | |
dc.contributor.author | Fernández Fernández, María Jesús | |
dc.contributor.author | Fernández Fernández, María Dolores | |
dc.date.accessioned | 2020-03-03T17:31:16Z | |
dc.date.available | 2020-03-03T17:31:16Z | |
dc.date.issued | 2020-02-21 | |
dc.identifier.citation | Nanomaterials 10(2) : (2020) // Article ID 376 | es_ES |
dc.identifier.issn | 2079-4991 | |
dc.identifier.uri | http://hdl.handle.net/10810/41921 | |
dc.description.abstract | Drug resistance of pathogenic microorganisms has become a global public health problem, which has prompted the development of new materials with antimicrobial properties. In this context, antimicrobial nanohybrids are an alternative due to their synergistic properties. In this study, we used an environmentally friendly one-step approach to synthesize graphene oxide (GO) decorated with silver nanoparticles (GO–AgNPs). By this process, spherical AgNPs of average size less than 4 nm homogeneously distributed on the surface of the partially reduced GO can be generated in the absence of any stabilizing agent, only with ascorbic acid (L-AA) as a reducing agent and AgNO<sub>3</sub> as a metal precursor. The size of the AgNPs can be controlled by the AgNO<sub>3</sub> concentration and temperature. Smaller AgNPs are obtained at lower concentrations of the silver precursor and lower temperatures. The antimicrobial properties of nanohybrids against Gram-negative bacteria <i>Escherichia coli</i> and <i>Pseudomonas aeruginosa</i>, Gram-positive <i>Staphylococcus aureus</i>, and the yeast <i>Candida albicans</i> were found to be concentration- and time-dependent. <i>C. albicans</i> and <i>S. aureus</i> showed the highest susceptibility to GO–AgNPs. These nanohybrids can be used as nanofillers in polymer nanocomposites to develop materials with antimicrobial activity for applications in different areas, and another potential application could be cancer therapeutic agents. | es_ES |
dc.description.sponsorship | This research was funded by the Basque Government (SAIOTEK S-PE13UN004 and GIC 15/78 IT990−16) and the University of The Basque Country (UFI11/56 and 11/25). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPÎ | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | |
dc.subject | graphene oxide | es_ES |
dc.subject | silver nanoparticles | es_ES |
dc.subject | nanohybrids | es_ES |
dc.subject | antimicrobial activity | es_ES |
dc.title | Graphene Oxide–Silver Nanoparticle Nanohybrids: Synthesis, Characterization, and Antimicrobial Properties | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.date.updated | 2020-03-02T12:41:08Z | |
dc.rights.holder | © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | es_ES |
dc.relation.publisherversion | https://www.mdpi.com/2079-4991/10/2/376 | es_ES |
dc.identifier.doi | 10.3390/nano10020376 | |
dc.departamentoes | Ciencia y tecnología de polímeros | es_ES |
dc.departamentoes | Inmunología, microbiología y parasitología | es_ES |
dc.departamentoeu | Immunologia, mikrobiologia eta parasitologia | es_ES |
dc.departamentoeu | Polimeroen zientzia eta teknologia | es_ES |
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Bestelakorik adierazi ezean, itemaren baimena horrela deskribatzen da:© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).