Browsing INVESTIGACIÓN by Author "Ubeda, María"

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      Testing a vaccine candidate against Hepatitis C virus designed by combinatorial optimization 

      Malaina Celada, Iker ORCID; Martínez Fernández, Luis ORCID; Salcines Cuevas, David; Terán Navarro, Héctor; Ocejo Vinyals, Javier Gonzalo; González López, Elena; Soriano, Vicente; Ubeda, María; Pérez Pinilla, Martín Blas ORCID; Martínez de la Fuente Martínez, Ildefonso Abel; Álvarez Domínguez, Carmen (Nature, 2023)
      This paper presents a new procedure for vaccine design against highly variable viruses such as Hepatitis C. The procedure uses an optimization algorithm to design vaccines that maximize the coverage of epitopes across ...