2021. Kimikako Nobel Saria natura imitatzeari. Biomimetikaren eragina organokatalisiaren garapene
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Date
2023Author
Prieto Aretxabaleta, Liher
Reyes Martín, Efraim
Uria Pujana, Uxue
Carrillo Fernández, María Luisa
Vicario Hernando, José Luis
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Ekaia 43 : 59-66 (2023)
Abstract
Prozesu biokimikoen behaketak eta ulerkuntzak ikertzailea inspiratu du entzimen jarrera antzeratzen duten molekula organiko bakunak aurkitzeko. 2021eko Kimikako Nobel Sariak biomimetikan oinarritutako organokatalisian egin den garapena nabarmendu du; gainera, organokatalizatzaileek zenbait abantaila ditzute jatorrizko aitzindari entzimatikoekin alderatuta, hautakortasun eta espezifikotasun hobetua erakusten baitute, besteak beste.; Observation and understanding of biochemical processes has inspired the researcher to find simple organic molecules that resemble the mechanism of action of certain enzymes. The 2021 Nobel Prize in Chemistry recognizes the development of organocatalysis which is based on biomimetics, but in comparison with enzime precur-sors organocatalysts have advantages, showing improved selectivity and specificity.