BackBrowsing INVESTIGACIÓN by Author "M. de Pancorbo, Marian"
Now showing items 21-40 of 40
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Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project
; ; ; ; Martínez de Pancorbo Gómez, María de los Angeles
; (Elsevier Science INC, 2019-10)
Introduction: Large variability among Alzheimer's disease (AD) cases might impact genetic discoveries and complicate dissection of underlying biological pathways. Methods: Genome Research at Fundacio ACE (GR@ACE) is a ... -
Influence of methyl donor nutrients as epigenetic regulators in colorectal cancer: A systematic review of observational studies
; ; Martínez de Pancorbo Gómez, María de los Angeles; (Baishideng, 2023)
BACKGROUNDDietary methyl donors might influence DNA methylation during carcinogenesis of colorectal cancer (CRC). However, whether the influence of methyl donor intake is modified by polymorphisms in such epigenetic ... -
Integración o preservación de las diferencias desde la perspectiva de la genética de las poblaciones humanas
Martínez de Pancorbo Gómez, María de los Angeles (Instituto Vasco de Criminología, 1995)
[ES] Partiendo de una exposición de la evolución de los derechos humanos, se analiza, desde la perspectiva de la Genética de las Poblaciones Humanas, la individualidad del ser humano, el origen común de la especie humana ... -
Límites de la tecnología basada en el ADN
Castro, Azucena; Fernández-Fernández, Isabel; Martínez de Pancorbo Gómez, María de los Angeles (Instituto Vasco de Criminología, 1998)
[ES] El perfil genético caracteriza a cualquier persona igual o mejor que sus huellas dactilares. Las aplicaciones del análisis del ADN de cara a la identificación genética son muy numerosas (diagnósticos de parentesco, ... -
Microtechnologies for Cell Microenvironment Control and Monitoring
Azuaje Hualde, Enrique; García Hernando, Maite ; Etxebarria Elezgarai, Jaione ; Martínez de Pancorbo Gómez, María de los Angeles ; Benito López, Fernando ; Basabe Desmonts, Lourdes (MDPI, 2017-06)
A great breadth of questions remains in cellular biology. Some questions cannot be answered using traditional analytical techniques and so demand the development of new tools for research. In the near future, the development ... -
Mitochondrial DNA Reveals the Trace of the Ancient Settlers of a Violently Devastated Late Bronze and Iron Ages Village
Núñez Domingo, Carolina; Baeta Bafalluy, Miriam; Cardoso Martín, Sergio; Palencia Madrid, Leire ; García Romero, Noemí; Llanos, Armando; Martínez de Pancorbo Gómez, María de los Angeles (Public Library Science, 2016-05-13)
La Hoya (Alava, Basque Country) was one of the most important villages of the Late Bronze and Iron Ages of the north of the Iberian Peninsula, until it was violently devastated around the 4th century and abandoned in the ... -
Naked Eye Y Amelogenin Gene Fragment Detection Using DNAzymes on a Paper-based Device
Azuaje Hualde, Enrique; Arroyo Jiménez, Susana; Garai Ibabe, Gaizka; Benito López, Fernando ; Martínez de Pancorbo Gómez, María de los Angeles (Elsevier, 2020-05-07)
Nowadays, there are strong efforts in developing new technology for rapid detection of specific DNA sequences for environmental monitoring, forensic analysis and rapid biomedical diagnosis applications. That is where ... -
New insights in the paternal genetic landscape of Southwestern Europe: dissection of haplogroup R1b-M269 and forensic applications
Villaescusa Urbaneja, Patricia (2019-03-29)
El cromosoma Y determina el sexo masculino y posee una naturaleza haploide que escapa a la recombinación, lo que hace que sólo esté presente en individuos varones y que se trasmita prácticamente sin cambios de padres a ... -
On-campus food purchase behaviors, choice determinants, and opinions on food availability in a Spanish university community
Martínez Pérez, Naiara; Telleria Aramburu, Nerea ; ; ; ; ; ; ; Martínez de Pancorbo Gómez, María de los Angeles ; Rocandio Pablo, Ana María ; (Elsevier, 2022-11)
Objective: The aim of this study was to investigate food purchasing behaviors, choice determinants, and opin-ions about on-campus food availability by a university community and to analyze differences in these aspects ... -
Optical Single Cell Resolution Cytotoxicity Biosensor Based onSingle Cell Adhesion Dot Arrays
García Hernando, Maite; Calatayud Sánchez, Alba ; ; Martínez de Pancorbo Gómez, María de los Angeles ; Benito López, Fernando ; Basabe Desmonts, Lourdes (American Chemical Society, 2020-05-28)
Low cost easy to use cell viability tests are needed in the pharmaceutical, biomaterial and environmental industry to measure adverse cellular effects. Herein we present a new methodology to track cell death with high ... -
Paper based microfluidic platform for single-step detection of mesenchymal stromal cells secreted VEGF
Azuaje Hualde, Enrique; Martínez de Pancorbo Gómez, María de los Angeles ; Benito López, Fernando ; Basabe Desmonts, Lourdes (Elsevier, 2022-03-22)
[EN] Low cost and user-friendly paper microfluidic devices, combined with DNA-based biosensors with binding capacities for specific molecules, have been proposed for the developing of novel platforms that ease and speed-up ... -
Potential relationship between single nucleotide polymorphisms used in forensic genetics and diseases or other traits in European population
; López López, Elixabet; ; García-Orad Carles, África ; Martínez de Pancorbo Gómez, María de los Angeles (Springer, 2015-03-13)
Single nucleotide polymorphisms (SNPs) are an interesting option to facilitate the analysis of highly degraded DNA by allowing the reduction of the size of the DNA amplicons. The SNPforID 52-plex panel is a clear example ... -
Protocolo de actuación para la recogida y registro de muestras entomológicas en una investigación pericial forense
Gil Arriortua, Maite; Urtiaga Villegas, Ailander; Martínez de Pancorbo Gómez, María de los Angeles; Saloña Bordas, Marta Inés (Instituto Vasco de Criminología, 2014)
[ES] Los artrópodos asociados a restos cadavéricos pueden aportar información fundamental que permita una estimación muy precisa del intervalo postmortem de un individuo (IPM). Por ello, su ... -
SIDA, el gran reto de un pequeño virus
Martínez de Pancorbo Gómez, María de los Angeles (Instituto Vasco de Criminología, 1991)
[ES] Los primeros caso de SIDA se diagnosticaron en 1981, entre joven es homosexuales de los Estados Unidos. Pronto quedó claro que todas las víctimas de SIDA sufrían una merma de una serie especifica de células del sistema ... -
Single nucleotide polymorphisms associated with susceptibility for development of colorectal cancer: Case-control study in a Basque population
; Aguirre Gómez, Carmelo; Bujanda Fernández de Pierola, Luis; Fernández Pablos, Francisco Javier; Polo, Francisco; Ordovás, José María; Etxezarraga Zuluaga, María Carmen; Zabalza Estévez, Ignacio; Larzabal, Mikel; Portillo Villares, María Isabel; Martínez de Pancorbo Gómez, María de los Angeles ; Palencia Madrid, Leire ; Rocandio Pablo, Ana María ; (Public Library Science, 2019-12-10)
Given the significant population diversity in genetic variation, we aimed to investigate whether single nucleotide polymorphisms (SNPs) previously identified in studies of colorectal cancer (CRC) susceptibility were also ... -
The COMT Val158 Met polymorphism as an associated risk factor for Alzheimer disease and mild cognitive impairment in APOE 4 carriers
Fernández Martínez, Manuel; Elcoroaristizabal Martín, Xabier; Galdos Alcelay, Luis; Castro Flores, Jessica; Uterga Valiente, Juan MarÍa; Indakoetxea Juanbeltz, Begoña; Gómez Beldarrain, María Angeles; Moraza López, Josefa; González Fernández, María Carmen; Molano Salazar, Ana; Bereincua Gandarias, Rocío; Inglés Borda, Sandra; Ortiz Marqués, Nuria; Barandiaran Amillano, Miryam; Carrasco Zabaleta, María; Martínez de Pancorbo Gómez, María de los Angeles (BioMed Central, 2009-09)
Background: The aim of this study is to examine the influence of the catechol-O-methyltranferase (COMT) gene (polymorphism Val158 Met) as a risk factor for Alzheimer's disease (AD) and mild cognitive impairment of amnesic ... -
The Expanded mtDNA Phylogeny of the Franco-Cantabrian Region Upholds the Pre-Neolithic Genetic Substrate of Basques
Cardoso Martín, Sergio; Valverde Potes, Laura; Alfonso Sánchez, Miguel Ángel; Palencia Madrid, Leire; Elcoroaristizabal Martín, Xabier; Algorta Pineda, Jaime; Catarino, Susana; Arteta, David; Herrera, Rene J.; Zarrabeitia, María Teresa; Peña García, José Ángel ; Martínez de Pancorbo Gómez, María de los Angeles (Public Library of Science, 2013-07-03)
The European genetic landscape has been shaped by several human migrations occurred since Paleolithic times. The accumulation of archaeological records and the concordance of different lines of genetic evidence during the ... -
The MAPT H1 Haplotype Is a Risk Factor for Alzheimer’s Disease in APOE ε4 Non-carriers
GR@ACE Study Group; DEGESCO Consortium; López de Munain Arregui, Adolfo José; Martínez de Pancorbo Gómez, María de los Angeles (Frontiers Media, 2019-12-04)
An ancestral inversion of 900 kb on chromosome 17q21, which includes the microtubule-associated protein tau (MAPT) gene, defines two haplotype clades in Caucasians (H1 and H2). The H1 haplotype has been linked inconsistently ... -
The Y chromosome of autochthonous Basque populations and the Bronze Age replacement
Rodriguez Luis, Javier; Palencia Madrid, Leire; Mendoza, Vivian C.; Garcia Bertrand, Ralph; Martínez de Pancorbo Gómez, María de los Angeles ; Herrera, Rene J. (Springer Nature, 2021-03-10)
Here we report on the Y haplogroup and Y-STR diversity of the three autochthonous Basque populations of Alava (n=54), Guipuzcoa (n=30) and Vizcaya (n=61). The same samples genotyped for Y-chromosome SNPs were typed for 17 ... -
X-chromosome markers in Forensic Genetics: Evaluation and development of a new 17 X-STR multiplex reaction
(2017-05-16)Actualmente, la demanda por los análisis de parentesco y la identificación genética se han convertido enun tema de interés social. Del mismo modo, la identificación de personas desaparecidas en desastres demasas, tanto ...