BackBrowsing INVESTIGACIÓN by Subject "NEUROLOGY"
Now showing items 1-20 of 23
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A genealogical map of the concept of habit
Barandiaran Fernández, Xabier Eugenio
; (Frontiers Research Foundation, 2014-07-21)
The notion of information processing has dominated the study of the mind for over six decades. However, before the advent of cognitivism, one of the most prominent theoretical ideas was that of Habit. This is a concept ... -
A novel form of human disease with a protease-sensitive prion protein and heterozygosity methionine/valine at codon 129: Case report
Rodríguez Martínez, Ana B.; Garrido Urkullu, Joseba M.; Zarranz Imirizaldu, Juan José; Arteagoitia, Jose M.; Martínez de Pancorbo Gómez, María de los Angeles; Atares, Begona; Bilbao, Miren J.; Ferrer, Isidro; Juste Jordán, Ramón A. (BioMed Central, 2010-10)
Background: Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare neurodegenerative disorder in humans included in the group of Transmissible Spongiform Encephalopathies or prion diseases. The vast majority of sCJD cases are ... -
Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimer's disease mouse model : mechanism for deficient glutamatergic transmission?
(BioMed Central, 2011-07-30)Astrocytes are fundamental for brain homeostasis and the progression and outcome of many neuropathologies including Alzheimer's disease (AD). In the triple transgenic mouse model of AD (3xTg-AD) generalised hippocampal ... -
Automated Segmentation of the Human Hippocampus Along Its Longitudinal Axis
(Human Brain Mapping, 2016)The human hippocampal formation is a crucial brain structure for memory and cognitive function that is closely related to other subcortical and cortical brain regions. Recent neuroimaging studies have revealed differences ... -
Bayesian longitudinal segmentation of hippocampal substructures in brain MRI using subject-specific atlases
(NeuroImage, 2016)The hippocampal formation is a complex, heterogeneous structure that consists of a number of distinct, interacting subregions. Atrophy of these subregions is implied in a variety of neurodegenerative diseases, most ... -
Behavioral profile of adults with Prader-Willi syndrome : correlations with individual and environmental variables
(BioMed Central, 2013)Background: Maladaptive behavior has been reported as a phenotypical feature in Prader–Willi syndrome (PWS). It severely limits social adaptation and the quality of life of children and adults with the syndrome. Different ... -
Brca1 is expressed in human microglia and is dysregulated in human and animal model of ALS
(Biomed Central, 2015-08-01)Background: There is growing evidence that microglia are key players in the pathological process of amyotrophic lateral sclerosis (ALS). It is suggested that microglia have a dual role in motoneurone degeneration through ... -
Cytokine pathway disruption in a mouse model of schizophrenia induced by Munc18-1a overexpression in the brain
Gil de la Pisa, Itziar; Cebrián, Carolina; Ortega Calvo, Jorge; Meana Martínez, José Javier; Sulzer, David (Biomed Central, 2014-07-29)
Background: An accumulating body of evidence points to the significance of neuroinflammation and immunogenetics in schizophrenia, and an imbalance of cytokines in the central nervous system (CNS) has been suggested to be ... -
Early astrocytic atrophy in the entorhinal cortex of a triple transgenic animal model of Alzheimer's disease
(Portland Press, 2011)The EC (entorhinal cortex) is fundamental for cognitive and mnesic functions. Thus damage to this area appears as a key element in the progression of AD (Alzheimer's disease), resulting in memory deficits arising from ... -
Enactivism is not interactionism
De Jaegher, Hanneke; (Frontiers Research Foundation, 2013-01)
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Evaluation of multi-echo ICA denoising for task based fMRI studies: Block designs, rapid event-related designs, and cardiac-gated fMRI
(NeuroImage, 2016)Multi-echo fMRI, particularly the multi-echo independent component analysis (ME-ICA) algorithm, has previously proven useful for increasing the sensitivity and reducing false positives for functional MRI (fMRI) based resting ... -
Fast and sequence-adaptive whole-brain segmentation using parametric Bayesian modeling
(NeuroImage, 2016)Quantitative analysis of magnetic resonance imaging (MRI) scans of the brain requires accurate automated segmentation of anatomical structures. A desirable feature for such segmentation methods is to be robust against ... -
FTY720 attenuates excitotoxicity and neuroinflammation
Cipriani, Raffaela; Chara Ventura, Juan Carlos; Rodríguez-Antigüedad Zarranz, Alfredo; (BioMed Central, 2015-05-08)
Background: FTY720 (fingolimod, Gilenya(TM)), a structural analog of sphingosine-1-phosphate (S1P), is the first oral drug approved for treatment the relapsing-remitting form of multiple sclerosis (MS), and its efficacy ... -
Increased expression of cystine/glutamate antiporter in multiple sclerosis
Pampliega Ormaetxea, Olatz; Domercq García, María ; Soria Lannes, Federico Nicolás ; ; ; (BioMed Central, 2011-06-03)
Background: Glutamate excitotoxicity contributes to oligodendrocyte and tissue damage in multiple sclerosis (MS). Intriguingly, glutamate level in plasma and cerebrospinal fluid of MS patients is elevated, a feature which ... -
Learning to perceive in the sensor motor approach: Piaget's theory of equilibration interpreted dynamically
Di Paolo, Ezequiel; Barandiaran Fernández, Xabier Eugenio; Beaton, Michael James Stuart; Buhrmann, Thomas (Frontiers Research Foundation, 2014-07-30)
Learning to perceive is faced with a classical paradox: if understanding is required for perception, how can we learn to perceive something new, something we do not yet understand? According to the sensorimotor approach, ... -
Modeling habits as self-sustaining patterns of sensorimotor behavior
; Barandiaran Fernández, Xabier Eugenio (Frontiers Research Foundation, 2014-08-08)
In the recent history of psychology and cognitive neuroscience, the notion of habit has been reduced to a stimulus-triggered response probability correlation. In this paper we use a computational model to present an ... -
Out-of-Synchrony Speech Entrainment in Developmental Dyslexia
(Human Brain Mapping, 2016)Developmental dyslexia is a reading disorder often characterized by reduced awareness of speech units. Whether the neural source of this phonological disorder in dyslexic readers results from the malfunctioning of the ... -
Risk factors for dementia in the epidemiological study of Munguialde County (Basque Country-Spain)
(BioMed Central, 2008-10-15)Background: Prevalence of degenerative dementias and dementias associated with cerebrovascular disease is increasing. Dementia is one of the most significant public health problem. In recent years, the role of vascular ... -
Sleep in children triggers rapid reorganization of memory-related brain processes
(NeuroImage, 2016)Behavioral evidence shows that sleep is crucial for the consolidation of declarative memories in children as in adults. However, the underlying cerebral mechanisms remain virtually unexplored. Using magnetoencephalography, ... -
Sleep not just protects memories against forgetting, it also makes them more accessible
(Cortex, 2016)Two published datasets (Dumay & Gaskell, 2007, Psychological Science; Tamminen, Payne, Stickgold, Wamsley, & Gaskell, 2010, Journal of Neuroscience) showing a positive influence of sleep on declarative memory were ...