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Desarrollo de nanopartículas sólidas lipídicas como sistemas de administración de ADN para terapia génica
(2013-10-24)
[EN] This work includes the development, characterization and optimization of a gene delivery system based on solid lipid nanoparticles (SLNs) . Formulations were characterized in terms of particle size , surface charge ...
Mechanism of transport of saquinavir-loaded nanostructured lipid carriers across the intestinal barrier
(Elsevier, 2013)
[EN] The aims of this work were (i) to evaluate the potential of nanostructured lipid carriers (NLCs) as a tool to 24
enhance the oral bioavailability of poorly soluble compounds using saquinavir (SQV), a BCS class IV ...
Dextran and protamine-based solid lipid nanoparticles as potential vectors for the treatment of X-linked juvenile retinoschisis
(Mary Ann Liebert, Inc., 2012-04)
[EN]The goal of the present study was to analyze the potential application of nonviral vectors based on solid lipid
nanoparticles (SLN) for the treatment of ocular diseases by gene therapy, specifically X-linked juvenile ...
The role of the cationic and helper lipids on niosomes for gene delivery applications: transfection of retina and brain as a main goal.
(2016-09-23)
Currently, gene delivery has become a tangible option for the treatment of several diseases. However, there are few available options in the market, where viral vectors are the preferred option due to their high transduction ...
Avances en el uso del plasma rico en factores de crecimiento en la regeneración periodontal.
(2018-12-20)
El envejecimiento global de la población está aumentando de manera acelerada. Estos cambios demográficos conllevan un aumento en la prevalencia de enfermedades crónicas y degenerativas relacionadas con la edad y asociadas ...
Terapias autólogas en dermatología regenerativa: la tecnología del plasma rico en factors de crecimiento.
(2019-07-11)
La medicina regenerativa definida como "un área interdisciplinar de la medicina dirigida a la reparación, reposición o regeneración de células, tejidos u órganos dañados estructural o funcionalmente", se postula como un ...
Tailored gelatin-based three-dimensional sysems for bone tissue engineering.
(2019-12-17)
The current Doctoral Thesis is focused on the development of three-dimensional systems for bone tissue engineering purposes. Gelatin was chosen as the main material to manufacture scaffolds capable for serving as both ...
Cationic Niosomes as Non-Viral Vehicles for Nucleic Acids: Challenges and Opportunities in Gene Delivery
(MDPI, 2019-02)
Cationic niosomes have become important non-viral vehicles for transporting a good number of small drug molecules and macromolecules. Growing interest shown by these colloidal nanoparticles in therapy is determined by their ...
Bioanthropology of obesity in a population of the Autonomus Community of the Basque Country
(2017-09-18)
Obesity has become a major health concern worldwide due to its increasing prevalence and its detrimental health impact. The overarching aim of the present thesis was to study the aetiology of obesity from anthropological, ...
Lipid Nanoparticles as Carriers for RNAi against Viral Infections: Current Status and Future Perspectives
(Hindawi Publishing, 2014)
The efforts made to develop RNAi-based therapies have led to productive research in the field of infections in humans, such as hepatitis C virus (HCV), hepatitis B virus (HBV), human immunodeficiency virus (HIV), human ...