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Pulmonary delivery of antibiotic-loaded lipid nanoparticles for the treatment of Pseudomonas aeruginosa infections associated with cystic fibrosis
(2016-05-19)
El objetivo principal de esta tesis doctoral es el desarrollo de nanopartículas lipídicas sólidas (SLN) y partículas lipídicas nanoestructuradas (NLC) como vehículos para facilitar la liberación de antibióticos, colistimetato ...
Blending Electronics with the Human Body: a Pathway Toward a Cybernetic Future
(Wiley, 2018-10)
At the crossroads of chemistry, electronics, mechanical engineering, polymer science, biology, tissue engineering, computer science, and materials science, electrical devices are currently being engineered that blend ...
Determination of optimal cryoprotectant agents for 3D cell-based products cryopreservation by slow freezing
(2018-12-12)
En esta tesis doctoral, se describen y se determinan los crioprotectores clave para la preservación de productos celulares 3D mediante la congelación lenta. Para ello, se han llevado a cabo los siguientes estudios: (i) ...
Plasma Rich in Growth Factors Membrane as Coadjuvant Treatment in the Surgery of Ocular Surface Disorders
(Lippincott Williams & Wilkins, 2018-04)
To evaluate the safety and efficacy of the surgical use of plasma rich in growth factors fibrin membrane (mPRGF) in different ocular surface pathologies.Fifteen patients with different corneal and conjunctival diseases ...
Differential profile of protein expression on human keratocytes treated with autologous serum and plasma rich in growth factors (PRGF)
(Public Library Science, 2018-10-12)
Purpose
The main objective of this study is to compare the protein expression of human keratocytes treated with Plasma rich in growth factors (PRGF) or autologous serum (AS) and previously induced to myofibroblast by ...
Preparation and Characterization of Resveratrol Loaded Pectin/Alginate Blend Gastro-Resistant Microparticles
(MDPI, 2018-08)
Background: The use of resveratrol as a dietary supplement is limited because it is easily oxidized and, after oral ingestion, it is metabolized into enterocytes and hepatocytes. Thus, new formulations are needed in order ...
Self-Healing Hydrogels: The Next Paradigm Shift in Tissue Engineering?
(Wiley, 2019-08-21)
Given their durability and long-term stability, self-healable hydrogels have, in the past few years, emerged as promising replacements for the many brittle hydrogels currently being used in preclinical or clinical trials. ...
Optimization and application of encapsulation technology for cell therapy in diabetes.
(2019-06-25)
El eje central de esta tesis doctoral consiste en la búsqueda del conjunto de técnicas más adecuadas para la obtención de células productoras de insulina diferenciadas a partir de células mesenquimales en el interior de ...
Terapia celular para el tratamiento de la enfermedad de Alzheimer: angiogénesis terapéutica inducida por células microencapsuladas secretoras del factor de crecimiento del endotelio vascular
(2013-10-02)
En la presente tesis doctoral se ha estudiado el potencial del VEGF como posible
tratamiento para la enfermedad de Alzheimer empleando como punto de partida la hipótesis vascular. La administración de dicho factor ...
Cell microencapsulation for therapeutic purposes: towards greater control over biocompatibility
(2012-04-17)
En la actualidad, los avances realizados en biología, genética y tecnología farmacéutica han permitido redefinir el concepto y las aplicaciones terapéuticas de la tecnología de
microencapsulación de células. Hoy en día ...