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Now showing items 37030-37049 of 39217
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Transannular Approach to 2,3-Dihydropyrrolo[1,2‑b]isoquinolin- 5(1H)‑ones through Brønsted Acid-Catalyzed Amidohalogenation
; ; ; Uria Pujana, Uxue
; Prieto Aretxabaleta, Liher ; ; Carrillo Fernández, María Luisa ; Vicario Hernando, José Luis (ACS. American Chemical Society, 2022-07-26)
A transannular approach has been developed for the construction of pyrrolo[1,2-b]isoquinolinones starting from benzofused nine-membered enelactams. This process takes place in the presence of a halogenating agent and under ... -
Transannular Enantioselective (3 + 2) Cycloaddition of Cycloalkenone Hydrazones under Bronsted Acid Catalysis.
Sendra, Jana; Reyes Martín, Efraim; Prieto Aretxabaleta, Liher; Fernández Gutiérrez, Elena; Vicario Hernando, José Luis (American Chemical Society, 2021-11-19)
[EN]Hydrazones derived from cycloalkenones undergo an enantioselective transannular formal (3 + 2) cycloaddition catalyzed by a chiral phosphoric acid. The reaction provides high yields and excellent stereocontrol in the ... -
Transartea. Arte-praktika kolaboratzaileak, teknologia erlazionalak eta performatibitate soziala
Del Olmo Alonso, Saioa (2018-11-16)
TRANSARTE es una investigación sobre proyectos artísticos relacionales creados a travésde procesos participativos y colaborativos, y sobre su capacidad para generartransformaciones e intercambios en el contexto en el que ... -
Transboundary Externalities in the Environmental Transition Hypothesis
Ansuategui Cobo, José Alberto; Perrings, Charles (1999-01)
The Environmental Kuznets Curve (EKC) is a hypothesis which implies that it is possible to "grow out of environmental degradation." Most theoretical models of the EKC relation have not accounted for transboundary and ... -
Transcription Factor Binding Site Enrichment Analysis In Co-Expression Modules In Celiac Disease
Romero Garmendia, Irati; García Etxebarria, Koldo; Hernández Vargas, Hector; ; ; Plaza Izurieta, Leticia; Cros, Marie-Pierre; Legarda Tamara, María; Irastorza Terradillos, Iñaki Xarles; Herceg, Zdenko; Fernández Jiménez, Nora ; Bilbao Catalá, José Ramón (MDPI, 2018-05-10)
The aim of this study was to construct celiac co-expression patterns at a whole genome level and to identify transcription factors (TFs) that could drive the gliadin-related changes in coordination of gene expression ... -
Transcription Factors in the Fungus Aspergillus nidulans: Markers of Genetic Innovation, Network Rewiring and Conflict between Genomics and Transcriptomics
Echeveste Juárez, Oier (MDPI, 2021-07-25)
Gene regulatory networks (GRNs) are shaped by the democratic/hierarchical relationships among transcription factors (TFs) and associated proteins, together with the cis-regulatory sequences (CRSs) bound by these TFs at ... -
Transcription of ribogenesis genes in fish gonads: Applications in the identification of stages of oogenesis and in environmental monitoring of intersex condition
Rojo Bartolomé, Iratxe; ; (Elsevier, 2017-06-13)
One of the best described effects of environmental xenoestrogens in fish is the generation of intersex gonads in males. Considering 5S rRNA a marker of the presence of oocytes, a 5S/18S rRNA index was calculated in 296 ... -
Transcriptional control of prostate cancer metabolism
(2017-12-18)La transformación y la progresión tumoral van acompañados de cambios metabólicos. Los principales co-reguladores metabólicos son capaces de orquestar la modulación de múltiples rutas metabólicas a través de la regulación ... -
Transcriptional deregulation of cell cycle by PGC1⍺ in prostate cancer
(2021-12-03)Prostate cancer (PCa) is the second most common cancer in men, only behind lung cancer. The development of precision medicine has become one of the main objectives for treating it and it seems increasingly crucial to find ... -
Transcriptional regulation of ASPA in prostate cancer cells
(2021-12-03)[EN] Prostate cancer (PCa) is a remarkably widespread disease. The role of modulator peroxisome proliferator-activated receptor gamma co-activator 1α (PGC1α) could be of distinguished relevance for diagnosis and treatment ... -
Transcriptional signatures of synaptic vesicle genes define myotonic dystrophy type I neurodegeneration
Jiménez Marín, Antonio; Díez Palacio, Ibai; Labayru Isusquiza, Garazi; Sistiaga Berrondo, Andone; Caballero, Maria C.; Andres-Benito, Pol; Sepulcre, Jorge; Ferrer, Isidro; López de Munain Arregui, Adolfo José; Cortés Díaz, Jesús María (Wiley, 2021-12)
Aim To delineate the neurogenetic profiles of brain degeneration patterns in myotonic dystrophy type I (DM1). Methods In two cohorts of DM1 patients, brain maps of volume loss (VL) and neuropsychological deficits (NDs) ... -
Transcriptome regulation network in Multiple sclerosis: Role of circular RNAs.
(2021-02-09)Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system, that leads to neurological disability. The disease course and clinical phenotype are highly variable and therefore, biomarkers that can ... -
Transcriptomic approach to identify biomarkers for primary progressive multiple sclerosis in populations of dendritic cells
(2022-09-16)[EN]Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) characterized by inflammation and demyelination as well as axonal and neuronal degeneration. To date, effective therapies to reverse ... -
Transcriptomic dataset for Sardina pilchardus: Assembly, annotation, and expression of nine tissues.
Langa Arranz, Jorge Eliseo; Huret, Martin; Montes Asperilla, Iratxe ; Conklin, Darrell; Estomba Recalde, Miren Andone (Elsevier, 2021-12)
[EN]European sardine or pilchard is a planktonic small pelagic fish present from the North Sea in Europe to the coast of Senegal in the North of Africa, and across the Mediterranean sea to the Black Sea. Ecologically, ... -
Transcriptomic meta-analysis reveals unannotated long non-coding RNAs related to the immune response in sheep
; Jugo Orrantia, Begoña Marina (Frontiers Media, 2022-11)
Long non-coding RNAs (lncRNAs) are involved in several biological processes, including the immune system response to pathogens and vaccines. The annotation and functional characterization of lncRNAs is more advanced in ... -
Transcriptomic profile reveals gender-specific molecular mechanisms driving multiple sclerosis progression
(Public Library Science, 2014-02-28)Background: Although the most common clinical presentation of multiple sclerosis (MS) is the so called Relapsing-Remitting MS (RRMS), the molecular mechanisms responsible for its progression are currently unknown. To tackle ... -
Transcutaneous Auricular Vagus Nerve Stimulation to Improve Emotional State
(MDPI, 2024-02-09)Emotional experiences are a part of our lives. The maladaptive functioning of an individual’s emotional field can lead to emotional disturbances of various kinds, such as anxiety and depression. Currently, there is an ... -
Transdisciplinar methodologies on medieval and post-medieval pottery analysis: an archaeometric approach to Basque and Riojan productions
Calparsoro Forcada, Estefanía (2019-06-07)
El eje central de la presente Tesis Doctoral es el análisis composicional de cerámicas arqueológicas, el cual es ampliamente utilizado en Arqueología para obtener profundizar en el conocimiento de las sociedades humanas ... -
Transdiscursividad fílmica, revisionismo y legitimación franquista: "¿Por qué morir en Madrid?" y su singularidad histórica
(Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2008)This article offers a perspective on the narrative strategies used in what might be labelled the "deliberate " documentary tradition which evoked the Civil War during the Seventies. Concretely, this research work studies ... -
Transediting Identity across Languages: Euronews coverage of Catalan Independence Aspirations
(Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2022)Our objective in this paper is to compare how lexical units created in Catalan discourse, and related to the aspirations of independence, are reproduced by Euronews in Spanish, English, German and French and how their ...