Examinar OpenAire por departamento (eus.) "Farmakologia"

Now showing items 1-5 of 5

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      GAT-3 Dysfunction Generates Tonic Inhibition in Exter nal Globus Pallidus Neurons in Parkinsonian Rodents 

      Chazalon, Marine; Paredes Rodríguez, Elena; Morin, Stéphanie; Martinez, Audrey; Cristóvão-Ferreira, Sofia; Vaz, Sandra; Sebastiao, Ana; Panatier, Aude; Boué-Grabot, Eric; Miguélez Palomo, Cristina; Baufreton, Jérôme (Cell Press, 2018-05-08)
      The external globus pallidus (GP) is a key GABAergic hub in the basal ganglia (BG) circuitry, a neuronal network involved in motor control. In Parkinson's disease (PD), the rate and pattern of activity of GP neurons are ...
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      Locus coeruleus norepinephrine activity mediates sensory-evoked awakenings from sleep 

      Hayat, Hanna; Regev, Noa; Matosevich, Noa; Sales, Anna; Paredes Rodríguez, Elena; Krom, Aaron J.; Berg, Lottem; Li, Yong; Lavigne, Marina; Kremer, Eric J.; Yizhar, Ofer; Pickering, Anthony E.; Nirl, Yuval (American Association for the Advancement of Science, 2020-04-08)
      A defining feature of sleep is reduced responsiveness to external stimuli, but the mechanisms mediating sensory-evoked arousal remain unclear. We hypothesized that reduced locus coeruleus (LC) norepinephrine (NE) activity ...
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      Long-term hippocampal interneuronopathy drives sex-dimorphic spatial memory impairment induced by prenatal THC exposure 

      De Salas Quiroga, Adán; García Rincón, Daniel; Gómez Domínguez, Daniel; Valero, Manuel; Simón Sánchez, Samuel; Paraíso Luna, Juan; Aguareles, José; Pujadas, Mitona; Muguruza Millán, Carolina ORCID; Callado Hernando, Luis Felipe ORCID; Lutz, Beat; Guzmán, Manuel; Menéndez de la Prida, Liset; Galve Roperh, Ismael (Nature, 2020-04)
      Prenatal exposure to Delta(9)-tetrahydrocannabinol (THC), the most prominent active constituent of cannabis, alters neurodevelopmental plasticity with a long-term functional impact on adult offspring. Specifically, THC ...
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      Opposite Alterations of 5¬HT2A Receptor Brain Density in Subjects with Schizophrenia: Relevance of Radiotracers Pharmacological Profile 

      Díez Alarcia, Rebeca ORCID; Muguruza Millán, Carolina ORCID; Rivero Calera, Guadalupe ORCID; García Bea, Aintzane; Gómez Vallejo, Vanessa; Callado Hernando, Luis Felipe ORCID; Llop Roig, Jordi ORCID; Martín Muñoz, Abraham; Meana Martínez, José Javier ORCID (Springer, 2021-05-20)
      The status of serotonin 5HT2A receptors (5HT2ARs) in schizophrenia has been controversial. In vivo positron emission tomography neuroimaging and in vitro post-mortem binding studies have reported conflicting results about ...
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      The endocannabinoid system in mental disorders: Evidence from human brain studies 

      Ibarra Lecue, Inés ORCID; Pilar Cuéllar, Fuencisla; Muguruza Millán, Carolina ORCID; Florensa Zanuy, Eva; Díaz, Álvaro; Urigüen Echeverría, Leyre ORCID; Castro, Elena; Pazos, Ángel; Callado Hernando, Luis Felipe ORCID (Elsevier, 2018-07-17)
      Mental disorders have a high prevalence compared with many other health conditions and are the leading cause of disability worldwide. Several studies performed in the last years support the involvement of the endocannabinoid ...