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Antitumoral actions of Vismia baccifera on human hepatocellular carcinoma HepG2
(2016-07-26)
Nowadays there is an increasing interest in finding bioactive compounds which can be used as chemopreventive agents against cancer. In this work, we have studied the antitumoral actions of aqueous extracts from leaves of ...
Ariketa fisikoaren eragina adineko pertsonen hauskortasunari lotutako parametroetan
(2019-02-11)
Tesi honek barne hartzen dituen bi proiektuak ausazko entsegu klinikoak izan dira. Helburu nagusia hirugarren adineko pertsona zaurgarrietan (batetik hirugarren adineko egoitzetako pertsonetan eta bestetik minbizia zuten ...
Role of TREM2 receptor during the progression of liver disease; from acute liver injury, to chronic liver disease and the development of hepatocellular carcinoma (HCC).
(2018-12-17)
La lesión e inflamación hepática y el desarrollo del carcinoma hepatocelular (HCC) se modulan en parte a través de la señalización de los receptores de tipo Toll (TLR). El receptor TREM2 (triggering receptor expressed on ...
SND1en gainadierazpenaren eragina hepatoma zeluletan: lipidoen metabolismoa eta tumoreen garapena
(2018-01-08)
SND1 is an evolutionarily conserved multifunctional protein. Although its function has not been fully elucidated yet, is considered a multifunctional protein participating, among others, in mRNA metabolism, gene transcription ...
Controlled ovarian hyperstimulation cycle: alterations in redox status of the follicular fluid.
(2019-07-23)
Los ciclos de hiperstimulación ovárica controlada son ampliamente utilizados en las técnicas de reproducción asistida debido al mayor número de óvulos que se obtienen por ciclo y al consecuente aumento de las probabilidades ...
Role of endoplasmic reticulum stress in the pathogenesis of polycystic liver disease: new potential therapeutic target
(2019-11-29)
La enfermedad hepática poliquística (PLD) abarca un grupo heterogéneo de colangiopatías genéticas caracterizadaspor la dilatación del conducto biliar y el desarrollo de múltiples quistes biliares intrahepáticos (>10), que ...
Nanoparticle-filled micelles as versatile delivery vehicles for TLR4 mediated immunotherapy
(2019-07-11)
Despite the tremendous potential of Toll-like receptor (TLR) 4 agonists in cancer immunotherapy, only some lipopolysaccharides (LPS) isolated from particular bacterial strains or synthetic structures like monophosphoryl ...
Study of the epigenetic cellular memory induced by morphine: a next generation sequencing approach
(2019-09-09)
Epigenetikak, kanpo faktoreek edo inguruneak norbanakoan izan dezaketen eragina aztertzen du. Azken urteetan, zenbait ikerketek erakutsi dutenez, inguruneak eragin zuzena izan dezake norbanako helduaren ezaugarri ...
Proteomic study of sperm-specific molecular mechanisms in human spermatozoa underlying sperm fertility.
(2019-01-18)
Eiakulatu berri diren giza espermatozoideak heldugabeak dira eta ugalkortasun ahalmena lortzeko emakumezkoaren ugaltze-traktuan zenbat aldaketa biokimiko eta fisiologiko pairatu behar dituzte. Sekuentzialki, espermatozoideek ...
Targeting mitochondria and post-traslational modifications: new promising approaches for the treatment of liver disease
(2017-04-24)
En esta tesis doctoral hemos corroborado que tanto una correcta función mitocondrial como la homeostasis de proteínas son fundamentales para el correcto funcionamiento del hígado y que alteraciones en ambos procesos están ...