Now showing items 7422-7441 of 11533

    • Thumbnail

      Novel Loci for Childhood Body Mass Index and Shared Heritability with Adult Cardiometabolic Traits 

      Vogelezang, Suzanne; Bradfield, Jonathan P.; Ahluwalia, Tarunveer S.; Curtin, John A.; Lakka, Timo A.; Grarup, Niels; Scholz, Markus; Van der Most, Peter J.; Monnereau, Claire; Stergiakouli, Evie; Heiskala, Anni; Horikoshi, Momoko; Fedko, Iryna O.; Vilor Tejedor, Natalia; Cousminer, Diana L.; Standl, Marie; Wang, Carol A.; Viikari, Jorma; Geller, Frank; Iñiguez, Carmen; Pitkanen, Niina; Chesi, Alessandra; Bacelis, Jonas; Yengo, Loic; Torrent, Maties; Ntalla, Ioanna; Helgeland, Oyvind; Selzam, Saskia; Vonk, Judith M.; Zafarmand, Mohammed H.; Heude, Barbara; Farooqi, Ismaa Sadaf; Alyass, Akram; Beaumont, Robin N.; Have, Christian T.; Rzehak, Peter; Bilbao Catalá, José Ramón ORCID; Schnurr, Theresia M.; Barroso, Ines; Bonnelykke, Klaus; Beilin, Lawrence J.; Carstensen, Lisbeth; Charles, Marie Aline; Chawes, Bo; Clement, Karine; Closa Monasterolo, Ricardo; Custovic, Adnan; Eriksson, Johan G.; Escribano, Joaquín; Groen-Blokhuis, Maria; Grote, Veit; Gruszfeld, Dariusz; Hakonarson, Hakon; Hansen, Torben; Hattersley, Andrew T.; Hollensted, Mette; Hottenga, Jouke Jan; Hypponen, Elina; Johansson, Stefan; Joro, Raimo; Kahonen, Mika; Karhunen, Ville; Kiess, Wieland; Knight, Bridget A.; Koletzko, Berthold; Kuehnapfel, Andreas; Landgraf, Kathrin; Langhendries, Jean-Paul; Lehtimaki, Terho; Leinonen, Jaakko T.; Li, Aihuali; Lindi, Virpi; Lowry, Estelle; Bustamante, Mariona; Medina Gómez, Carolina; Melbye, Mads; Michaelsen, Kim F.; Morgen, Camilla S.; Mori, Trevor A.; Nielsen, Tenna R. H.; Niinikoski, Harri; Oldehinkel, Albertine J.; Pahkala, Katja; Panoutsopoulou, Kalliope; Pedersen, Oluf; Pennell, Craig E.; Power, Christine; Reijneveld, Sijmen A.; Rivadeneira, Fernando; Simpson, Angela; Sly, Peter D.; Stokholm, Jakob; Teo, Kook K.; Thiering, Elisabeth; Timpson, Nicholas J.; Uitterlinden, Andre G.; Van Beijsterveldt, Catharina E. M.; Van Schaik, Barbera D. C.; Vaudel, Marc; Verduci, Elvira; Vinding, Rebecca K.; Vogel, Mandy; Zeggini, Eleftheria; Sebert, Sylvain; Lind, Mads V.; Brown, Christopher D.; Santa Marina, Loreto; Reischl, Eva; Frithioff-Bojsoe, Christine; Meyre, David; Wheeler, Eleanor; Ong, Ken; Nohr, Ellen A.; Vrijkotte, Tanja G. M.; Koppelman, Gerard H.; Plomin, Robert; Njolstad, Pal R.; Dedoussis, George D.; Froguel, Philippe; Sorensen, Thorkild I. A.; Jacobsson, Bo; Freathy, Rachel M.; Zemel, Babette S.; Raitakari, Olli; Vrijheid, Martine; Feenstra, Bjarke; Lyytikainen, Leo-Pekka; Snieder, Harold; Kirsten, Holger; Holt, Patrick G.; Heinrich, Joachim; Widen, Elisabeth; Sunyer, Jordi; Boomsma, Dorret I.; Jarvelin, Marjo-Riitta; Koerner, Antje; Smith, George Davey; Holm, Jens-Christian; Atalay, Mustafa; Murray, Clare; Bisgaard, Hans; McCarthy, Mark I.; Jaddoe, Vincent W. V.; Grant, Struan F. A.; Felix, Janine F. (Public Library Science, 2020-10-12)
      The genetic background of childhood body mass index (BMI), and the extent to which the well-known associations of childhood BMI with adult diseases are explained by shared genetic factors, are largely unknown. We performed ...
    • Thumbnail

      Novel Mean-Type Inequalities via Generalized Riemann-Type Fractional Integral for Composite Convex Functions: Some Special Examples 

      Mukhtar, Muzammil; Yaqoob, Muhammad; Samraiz, Muhammad; Shabbir, Iram; Etemad, Sina; De la Sen Parte, Manuel ORCID; Rezapour, Shahram (MDPI, 2023-02-10)
      This study deals with a novel class of mean-type inequalities by employing fractional calculus and convexity theory. The high correlation between symmetry and convexity increases its significance. In this paper, we first ...
    • Thumbnail

      Novel Methodology for the Detection of Enveloped Viruses 

      Resa Infante, Patricia; Erkizia, Itziar; Nieto Garai, Jon Ander; Lorizate Nogales, Maier; Izquierdo Useros, Nuria; Martínez Picado, Javier (MDPI, 2020-06-15)
      Viral infections in humans cause a huge burden in worldwide healthcare that has increased due to the emergence of new pathogenic viruses, such as in the recent Ebola virus (EBOV) outbreaks. Viral particles in body fluids ...
    • Thumbnail

      Novel Papillomaviruses in Free-Ranging Iberian Bats: No Virus-Host Co-evolution, No Strict Host Specificity, and Hints for Recombination 

      García Pérez, Raquel; Ibáñez, Carlos; Godínez, José M.; Aréchiga, Nidia; Garín Atorrasagasti, Ignacio ORCID; Pérez Suárez, Gonzalo; De Paz, Oscar; Juste, Javier; Echevarría, Juan E.; Bravo, Ignacio G. (Oxford University Press, 2014)
      Papillomaviruses (PVs) are widespread pathogens. However, the extent of PV infections in bats remains largely unknown. This work represents the first comprehensive study of PVs in Iberian bats. We identified four novel PVs ...
    • Thumbnail

      Novel phosphine sulphide gold(I) complexes: topoisomerase I inhibitors and antiproliferative agents 

      Martín Encinas, Endika; Cornejo Rodríguez, Verónica; Miguel, Jesús Ángel; Martinez-Ilarduya, Jesus M.; Rubiales Alcaine, María Gloria ORCID; Knudsen, Birgitta R.; Palacios Gambra, Francisco Javier ORCID; Alonso Pérez, Concepción Estibaliz ORCID (RSC, 2020-05-20)
      This work describes the synthesis of the gold(I) complexes of phosphine sulphides. The formation of these new derivatives has been confirmed by X-ray crystallography. The coordination of gold(I) with the sulphur atom of ...
    • Thumbnail

      Novel Pixelwise Co-Registered Hematoxylin-Eosin and Multiphoton Microscopy Image Dataset for Human Colon Lesion Diagnosis 

      Picón Ruiz, Artzai ORCID; Terradillos Fernández, Elena; Sánchez Peralta, Luisa F.; Mattana, Sara; Cicchi, Riccardo; Blover, Benjamin J.; Arbide del Río, Nagore; Velasco Arteche, Jacques; Etxezarraga Zuluaga, María Carmen; Pavone, Francesco S.; Garrote Contreras, Estíbaliz; López Saratxaga, Cristina (Elsevier, 2022-02-07)
      Colorectal cancer presents one of the most elevated incidences of cancer worldwide. Colonoscopy relies on histopathology analysis of hematoxylin-eosin (H&E) images of the removed tissue. Novel techniques such as multi-photon ...
    • Thumbnail

      Novel Population Pharmacokinetic Model for Linezolid in Critically Ill Patients and Evaluation of the Adequacy of the Current Dosing Recommendation 

      Soraluce Olañeta, Amaia; Barrasa González, Helena; Asín-Prieto, Eduardo; Sánchez Izquierdo, José Ángel; Maynar, Javier; Isla Ruiz, Arantxazu ORCID; Rodríguez Gascón, Alicia (MDPI, 2020-01-09)
      Antimicrobial treatment in critically ill patients remains challenging. The aim of this study was to develop a population pharmacokinetic model for linezolid in critically ill patients and to evaluate the adequacy of ...
    • Thumbnail

      Novel Sol-Gel Route to Prepare Eu3+-Doped 80SiO2-20NaGdF4 Oxyfluoride Glass-Ceramic for Photonic Device Applications 

      Cruz, María Eugenia; Ngoc Lam Tran, Thi; Chiasera, Alessandro; Durán, Alicia; Fernández Rodríguez, Joaquín Manuel; Balda de la Cruz, Rolindes ORCID; Castro, Yolanda (MDPI, 2023-03-05)
      Oxyfluoride glass-ceramics (OxGCs) with the molar composition 80SiO2-20(1.5Eu3+: NaGdF4) were prepared with sol-gel following the “pre-crystallised nanoparticles route” with promising optical results. The preparation of ...
    • Thumbnail

      Novel Thermal Management Strategy for Improved Inverter Reliability in Electric Vehicles 

      Trancho Olabarri, Elena ORCID; Ibarra Basabe, Edorta ORCID; Prieto, Pablo; Arias, Antoni; Lis, Adrian; Pai, Ajay Poonjal (MDPI, 2020-11-12)
      Requirements for electric vehicle (EV) propulsion systems—i.e., power density, switching frequency and cost—are becoming more stringent, while high reliability also needs to be ensured to maximize a vehicle’s life-cycle. ...
    • Thumbnail

      Novel topoisomerase I inhibitors. Syntheses and biological evaluation of phosphorus substituted quinoline derivates with antiproliferative activity 

      Alonso Pérez, Concepción Estibaliz ORCID; Fuertes Sánchez, María ORCID; Martín Encinas, Endika; Selas Lanseros, Asier; Rubiales Alcaine, María Gloria ORCID; Tesauro, Cinzia; Knudsen, Birgitta K.; Palacios Gambra, Francisco Javier ORCID (Elsevier, 2018-02-22)
      This work describes the synthesis of 1,2,3,4-tetrahydroquinolinylphosphine oxides, phosphanes and phosphine sulfides as well as that of quinolinylphosphine oxides and phosphine sulfides, which were synthesized in good to ...
    • Thumbnail

      Novel Transcript Discovery Expands the Repertoire of Pathologically-Associated, Long Non-Coding RNAs in Vascular Smooth Muscle Cells 

      Bennett, Matthew; Ulitsky, Igor; Alloza Moral, Iraide; Vandenbroeck, Koen; Miscianinov, Vladislav; Mahmoud, Amira Dia; Ballantyne, Margaret; Rodor, Julie; Baker, Andrew H. (MDPI, 2021-02-02)
      Vascular smooth muscle cells (VSMCs) provide vital contractile force within blood vessel walls, yet can also propagate cardiovascular pathologies through proliferative and pro-inflammatory activities. Such phenotypes are ...
    • Thumbnail

      Novel Variant in the CNNM2 Gene Associated with Dominant Hypomagnesemia 

      García Castaño, Alejandro; Madariaga Domínguez, Leire ORCID; Antón Gamero, Montserrat; Mejia, Natalia; Ponce, Jenny; Gómez Conde, Sara; Pérez de Nanclares, Gustavo; De la Hoz, Ana Belén; Martínez Salazar, Rosa; Saso Jiménez, Laura; Martínez de la Piscina Martín, Idoia; Urrutia, Inés; Velasco, Olaia; Aguayo Calcena, Aníbal; Castaño González, Luis Antonio ORCID; Gaztambide Sáenz, María Sonia (Public Library Science, 2020-09-30)
      The maintenance of magnesium (Mg2+) homeostasis is essential for human life. The Cystathionine-beta-synthase (CBS)-pair domain divalent metal cation transport mediators (CNNMs) have been described to be involved in maintaining ...
    • Thumbnail

      La novela erótica griega: Dafnis y Cloe de Longo 

      Redondo Moyano, Elena ORCID (Euskal Herriko Unibertsitateko Argitalpen Zerbitzua / Servicio Editorial de la Universidad del País Vasco, 2011)
      La obra de Longo pertenece al grupo de las “novelas de amor y aventuras”, ya que relata una historia de amor mutuo entre una pareja heterosexual de bellos adolescentes pertenecientes a las clases altas de la sociedad, los ...
    • Thumbnail

      La novela y el surgimiento del neocatolicismo en España. Una interpretación de género 

      Mínguez Blasco, Raúl (UNED, 2017)
      A mediados del siglo XIX se produjo una importante transformación en la visión de muchos católicos respecto de la novela. De considerarse un género corruptor de la sociedad y especialmente peligroso para las mujeres, pasó ...
    • Thumbnail

      NPG–TRIS Thermal Storage System. Quantification of the Limiting Processes: Sublimation and Water’s Adsorption 

      De La Pinta Alonso, Noelia; Santos Moreno, Sergio; Doppiu, Stefania; Igartua Aldamiz, Josu Mirena ORCID; Palomo del Barrio, Elena; López, Gabriel Alejandro ORCID (MDPI, 2021-10-05)
      The NPG–TRIS binary system (NPG = (CH3)2C(CH2OH)2 = 2,2-dimetyl-1,3-propanodiol; TRIS = NH2C(CH2OH)3 = 2-Amino-2-(hydroxymethyl)-1,3-propanediol) was intensively investigated as a thermal energy storage system, due to the ...
    • Thumbnail

      NRN1 Gene as a Potential Marker of Early-Onset Schizophrenia: Evidence from Genetic and Neuroimaging Approaches 

      Almodóvar-Payá, Carmen; Guardiola-Ripoll, Maria; Giralt-López, Maria; Gallego, Carme; Salgado-Pineda, Pilar; Miret, Salvador; Salvador, Raymond; Muñoz, María J.; Lázaro, Luisa; Guerrero-Pedraza, Amalia; Parellada, Mara; Carrión, María I.; Cuesta, Manuel J.; Maristany, Teresa; Sarró, Salvador; Fañanás, Lourdes; Callado Hernando, Luis Felipe ORCID; Arias, Bárbara; Pomarol-Clotet, Edith; Fatjó-Vilas, Mar (MDPI, 2022)
      Included in the neurotrophins family, the Neuritin 1 gene (NRN1) has emerged as an attractive candidate gene for schizophrenia (SZ) since it has been associated with the risk for the disorder and general cognitive performance. ...
    • Thumbnail

      Nuclear energy: Twitter data mining for social listening analysis 

      Zarrabeitia Bilbao, Enara ORCID; Jaca-Madariaga Ominetti, Maite; Río Belver, Rosa María ORCID; Álvarez Meaza, Izaskun ORCID (Springer, 2023)
      Knowing the presence, attitude and sentiment of society is important to promote policies and actions that influence the development of different energy sources and even more so in the case of an energy source such as ...
    • Thumbnail

      Nucleation and crystallization in bio-based immiscible polyester blends 

      Fenni, Seif Eddine; Cavallo, Dario; Müller Sánchez, Alejandro Jesús ORCID (Springer, 2019-08-21)
      Bio-based thermoplastic polyesters are highly promising materials as they combine interesting thermal and physical properties and in many cases biodegradability. However, sometimes the best property balance can only be ...
    • Thumbnail

      Nucleation and Crystallization of PA6 Composites Prepared by T-RTM: Effects of Carbon and Glass Fiber Loading 

      Zaldua Carazo, Nerea; Maiz, Jon; De la Calle, Amaia; Garcia Arrieta, Sonia; Elizetxea, Cristina; Harismendy, Isabel; Tercjak Sliwinska, Agnieszka; Müller Sánchez, Alejandro Jesús ORCID (MDPI, 2019-10-14)
      Thermoplastic resin transfer molding (T-RTM) is attracting much attention due to the need for recyclable alternatives to thermoset materials. In this work, we have prepared polyamide-6 (PA6) and PA6/fiber composites by ...
    • Thumbnail

      Nucleation modalities in poly(lactide), poly(butylene succinate) and poly(ε-caprolactone) ternary blends with partial wetting morphology 

      Fenni, Seif Eddine; Wang, Jun; Haddaoui, Nacerddine; Favis, Basil D.; Müller Sánchez, Alejandro Jesús ORCID; Cavallo, Dario (John Wiley & Sons, Inc., 2020-08-17)
      Ternary biodegradable polymer blends of poly(lactic acid) (PLA), poly(butylene succinate) (PBS), and poly(ε‐caprolactone) (PCL) with the composition 45/10/45 wt% and exhibiting partial‐wetting morphology were prepared. In ...