Now showing items 81-100 of 175

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      Herramienta Informática VALINTAN (www.valintan.com) de Valoración Geriátrica para Atención Primaria 

      Martín Lesende, Iñaki; Mendibil Crespo, Luis Ignacio; Berrizbeitia González, Amaia; Llamosas Luengo, Iker (Doyma, 2020-10)
      la herramienta VALINTAN en http://www.valintan.com (fig. 1). Consiste en una herramienta informatizada y facilitada de valoración multidimensional tipo valoración geriátrica integral (VGI) pensada para ser utilizada por ...
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      Hidroxicloroquina en el tratamiento de las enfermedades autoinmunes sistémicas 

      Danza, Álvaro; Graña, Diego; Goñi, Mabel; Vargas, Andrea; Ruiz Irastorza, Guillermo (Sociedad Médica Santiago, 2016-02)
      Hydroxychloroquine (HCQ) is by far the most frequently used antimalarial for the management of Systemic Autoimmune Diseases. It has immunomodulatory, hypolipidemic, hypoglycemic and antithrombotic properties and it diminishes ...
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      Hole-in-one: simple non-surgical technique for the management of anterior chamber migrated Ozurdex implant 

      Rivera Pérez de Rada, Pablo; Fernández Avellaneda, Pedro; Barturen Herraiz, Lucia Teresa; Henares Fernández, Iker; Ispizua Mendivil, Estibaliz; Castellanos Relloso, María Ángeles; Hidalgo Santamaría, Javier; Grijalvo López, Jesús Alfonso (GMS, 2020-02-27)
      Introduction: The migration of a dexamethasone implant to the anterior chamber is a vision-threatening complication which can happen in non-compartmentalized eyes treated with this device. Previous literature suggests that ...
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      Identification of a Novel Candidate Gene for Serrated Polyposis Syndrome Germline Predisposition by Performing Linkage Analysis Combined With Whole-Exome Sequencing 

      Toma, Claudio; Díaz Gay, Marcos; Soares de Lima, Yasmin; Arnau Collell, Coral; Franch Expósito, Sebastià; Muñoz, Jenifer; Overs, Bronwyn; Bonjoch, Laia; Carballal, Sabela; Ocaña, Teresa; Cuatrecasas, Miriam; Díaz de Bustamante, Aranzazu; Castells, Antoni; Bujanda Fernández de Pierola, Luis ORCID; Cubiella, Joaquín; Balaguer, Francesc; Rodríguez Alcalde, Daniel; Fullerton, Janice M.; Castellví-Bel, Sergi (Lippincott Williams & Wilkins, 2019-09-19)
      OBJECTIVES: Serrated polyposis syndrome (SPS) is a complex disorder with a high risk of colorectal cancer for which the germline factors remain largely unknown. Here, we combined whole-exome sequencing (WES) and linkage ...
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      Immune Checkpoint Inhibitors: The Emerging Cornerstone in Cholangiocarcinoma Therapy? 

      Gutiérrez Larrañaga, María; González López, Elena; Roa Bautista, Adriel; Rodrigues, Pedro M.; Díaz González, Álvaro; Bañales Asurmendi, Jesús María ORCID; López Hoyos, Marcos; Santos Laso, Álvaro; Crespo, Javier (Karger, 2021-09)
      [EN]Background: Cholangiocarcinoma (CCA) encompasses a heterogeneous group of malignant tumors with dismal prognosis and increasing incidence worldwide. Both late diagnosis due to the lack of early symptoms and the refractory ...
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      Impact of chronic hepatitis C on mortality in cirrhotic patients admitted to intensive-care unit 

      Álvaro Meca, Luis Alejandro; Jiménez-Sousa, María A.; Boyer, Alexandre; Medrano Laporte, José ORCID; Reulen, Holger; Kneib, Thomas; Resino, Salvador (Biomed Central, 2016-03-12)
      Background: Cirrhosis and severe sepsis are factors associated with increased mortality in intensive care unit (ICU), but chronic hepatitis C (CHC) has been less studied in ICU. The aim of this study was to analyze the ...
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      Impact of COVID-19 pandemic on the PREDIMED-Plus randomized clinical trial: Effects on the interventions, participants follow-up, and adiposity 

      Alonso Gómez, Ángel María ORCID; PREDIMED-PLUS Investigators (Frontiers Media, 2023-01)
      Background: The COVID-19 pandemic has affected the implementation of most ongoing clinical trials worldwide including the PREDIMED-Plus study. The PREDIMED-Plus is an ongoing, multicenter, controlled intervention trial, ...
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      Impact of Positive Lymph Nodes and Resection Margin Status on the Overall Survival of Patients with Resected Perihilar Cholangiocarcinoma: The ENSCCA Registry 

      Nooijen, Lynn E.; Bañales Asurmendi, Jesús María ORCID; De Boer, Marieke T.; Braconi, Chiara; Folseraas, Trine; Forner, Alejandro; Holowko, Waclaw; Hoogwater, Frederik J. H.; Klümpen, Heinz-Josef; Groot Koerkamp, Bas; Lamarca, Angela; Lacasta, Adelaida; López López, Flora; Izquierdo Sánchez, Laura; Scheiter, Alexander; Utpatel, Kirsten; Swijnenburg, Rutger-Jan; Kazemier, Geert; Erdmann, Joris I. (MDPI, 2022-05-12)
      Background: Lymph node metastasis and positive resection margins have been reported to be major determinants of overall survival (OS) and poor recurrence-free survival (RFS) for patients who underwent resection for perihilar ...
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      Incidence of Diabetes Mellitus and Associated Risk Factors in the Adult Population of the Basque Country, Spain 

      Urrutia, Inés; Martín Nieto, Alicia; Martínez Salazar, Rosa; Casanovas Marsal, Josep Oriol; Aguayo Calcena, Aníbal; Del Olmo, Juan; Arana Arri, Eunate; Fernández Rubio, Elsa; Castaño González, Luis Antonio ORCID; Gaztambide Sáenz, María Sonia (Nature, 2021-02-04)
      The aim of this study was to estimate the incidence of diabetes mellitus in the Basque Country and the risk factors involved in the disease by reassessing an adult population after 7 years of follow-up. In the previous ...
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      Increased incidence of giant cell arteritis and associated stroke during the COVID-19 pandemic in Spain: A nation-wide population study 

      Moreno Torres, Víctor; Soriano, Vicente; Calderón Parra, Jorge; Martínez Urbistondo, María; Treviño, Ana; de San Vicente, Zayrho; de Mendoza, Carmen; Ruiz Irastorza, Guillermo (Elsevier, 2023-06)
      Introduction SARS-CoV-2 infection and COVID-19 vaccines might have increased the incidence of giant-cell arteritis (GCA) and the risk of associated stroke in Spain. Methods Retrospective nation-wide observational ...
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      Increased Th17-Related Cytokine Serum Levels in Patients With Multiple Polyps of Unexplained Origin 

      Alustiza, Miren; Hernández Illán, Eva; Juárez, Miriam; Giner Calabuig, Mar; Mira, Cristina; Martínez Roca, Alejandro; Bujanda Fernández de Pierola, Luis ORCID; Rodríguez Moranta, Francisco; Cubiella, Joaquín; De Castro, Luisa; Marín Gabriel, José Carlos; Herreros de Tejada, Alberto; Fernández Bañares, Fernando; Nicolás Pérez, David; Giménez, Paula; Martínez Cardona, Claudia; Francés, Rubén; Murcia, Oscar; Jover, Rodrigo (Wolters Kluwer, 2020-03)
      OBJECTIVES: Most patients with multiple colonic polyps do not have a known genetic or hereditary origin. Our aim was to analyze the presence of inflammatory cytokines and levels of glucose, insulin, and C-reactive protein ...
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      Infective endocarditis in hypertrophic cardiomyopathy A multicenter, prospective, cohort study 

      Dominguez, Fernando; Ramos, Antonio; Bouza, Emilio; Muñoz, Patricia; Valerio, Maricela C.; Fariñas, Carmen; De Berrazueta, José Ramón; Zarauza, Jesús; Pericás Pulido, Juan Manuel; Paré, Juan Carlos; De Alarcón, Arístides; Sousa, Dolores; Rodriguez Bailón, Isabel; Montejo Baranda, José Miguel; Noureddine, Mariam; García Vázquez, Elisa; Garcia-Pavia, Pablo (Lippincott Williams & Wilkins, 2016-06)
      Infective endocarditis (IE) complicating hypertrophic cardiomyopathy (HCM) is a poorly known entity. Although current guidelines do not recommend IE antibiotic prophylaxis (IEAP) in HCM, controversy remains.This study ...
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      Inflammatory Markers and Obstructive Sleep Apnea in Obese Children: The NANOS Study 

      Gileles Hillel, Alex; Alonso Álvarez, María Luz; Kheirandish Gozal, Leila; Peris, Eduard; Cordero Guevara, José Aurelio; Terán Santos, Joaquín; González Martínez, Mónica; Jurado Luque, María José; Corral Peñafiel, Jaime; Durán Cantolla, Joaquín; Gozal, David (Hindawi Publishing, 2014)
      Introduction. Obesity and obstructive sleep apnea syndrome (OSA) are common coexisting conditions associated with a chronic low-grade inflammatory state underlying some of the cognitive, metabolic, and cardiovascular ...
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      Inflammatory Mediators of Hepatic Steatosis 

      Hijona Muruamendiaraz, Elizabeth; Hijona Muruamendiaraz, Lander; Arenas Mirave, Juan Ignacio; Bujanda Fernández de Pierola, Luis ORCID (Hindawi Publishing Corporation, 2010)
      Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming a world-wide public health problem. NAFLD represents a spectrum of disease ranging from “simple steatosis”, which is considered relatively benign, to nonalcoholic ...
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      Influence of MUC5B gene on antisynthetase syndrome 

      López Mejías, Raquel; Remuzgo Martínez, Sara; Genre, Fernanda; Pulito Cueto, Verónica; Fernández Rozas, Sonia M.; Llorca, Javier; Iturbe Fernández, David; Mora Cuesta, Víctor M.; Ortego Centeno, Norberto; Pérez Gómez, Nair; Mera Varela, Antonio; Martínez Barrio, Julia; López Longo, Francisco Javier; Mijares, Verónica; Lera Gómez, Leticia; Usetti, María Piedad; Laporta, Rosalía; Pérez, Virginia; De Pablo Gafas, Alicia; Alfranca González, María Aránzazu; Calvo Alén, Jaime; Romero Bueno, Fredeswinda; Sánchez Pernaute, Olga; Nuño Nuño, Laura; Bonilla, Gema; Balsa, Alejandro; Hernández González, Fernanda; Grafia, Ignacio; Prieto González, Sergio; Narvaez, Javier; Trallero Araguas, Ernesto; Selva O’Callaghan, Albert; Gualillo, Oreste; Castañeda, Santos; Cavagna, Lorenzo; Cifrian, José M.; González Gay, Miguel A. (Nature, 2020-01-29)
      MUC5B rs35705950 (G/T) is strongly associated with idiopathic pulmonary fibrosis (IPF) and also contributes to the risk of interstitial lung disease (ILD) in rheumatoid arthritis (RA-ILD) and chronic hypersensitivity ...
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      Influence of MUC5B gene on antisynthetase syndrome 

      López Mejías, Raquel; Remuzgo Martínez, Sara; Genre, Fernanda; Pulito Cueto, Verónica; Fernández Rozas, Sonia M.; Llorca, Javier; Iturbe Fernández, David; Mora Cuesta, Víctor M.; Ortego Centeno, Norberto; Pérez Gómez, Nair; Mera Varela, Antonio; Martínez Barrio, Julia; López Longo, Francisco Javier; Mijares, Verónica; Lera Gómez, Leticia; Usetti, María Piedad; Laporta, Rosalía; Pérez, Virginia; De Pablo Gafas, Alicia; Alfranca González, María Aránzazu; Calvo Alén, Jaime; Romero Bueno, Fredeswinda; Sanchez Pernaute, Olga; Nuno, Laura; Bonilla, Gema; Balsa, Alejandro; Hernández González, Fernanda; Grafia, Ignacio; Prieto González, Sergio; Narváez, Javier; Trallero Araguas, Ernesto; Selva O’Callaghan, Albert; Gualillo, Oreste; Castañeda, Santos; Cavagna, Lorenzo; Cifrian, José M.; González Gay, Miguel A. (Nature, 2020-01-29)
      MUC5B rs35705950 (G/T) is strongly associated with idiopathic pulmonary fibrosis (IPF) and also contributes to the risk of interstitial lung disease (ILD) in rheumatoid arthritis (RA-ILD) and chronic hypersensitivity ...
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      Inhibition of NAE-dependent protein hyper-NEDDylation in cystic cholangiocytes halts cystogenesis in experimental models of polycystic liver disease 

      Lee-Law, Pui Y.; Olaizola Rebe, Paula; Caballero Camino, Francisco Javier ORCID; Izquierdo Sánchez, Laura; Rodrigues, Pedro M.; Perugorria Montiel, María Jesús; Azkargorta, Mikel; Elortza, Felix; Martínez Chantar, María Luz ORCID; Aspichueta Celaá, Patricia; Bujanda Fernández de Pierola, Luis ORCID; Drenth, Joost P. H.; Bañales Asurmendi, Jesús María ORCID (Sage, 2021-09)
      Background Polycystic liver diseases (PLDs) are genetic inherited disorders characterized by the progressive growth of numerous intrahepatic biliary cysts, which are the main cause of morbidity. Previous studies revealed ...
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      Integrated Analysis of Germline and Tumor DNA Identifies New Candidate Genes Involved in Familial Colorectal Cancer 

      Díaz Gay, Marcos; Franch Expósito, Sebastià; Arnau Collell, Coral; Park, Solip; Supek, Fran; Muñoz, Jenifer; Bonjoch, Laia; Gratacós Mulleras, Anna; Sánchez Rojas, Paula A.; Esteban-Jurado, Clara; Ocaña, Teresa; Cuatrecasas, Miriam; Vila Casadesús, Maria; Lozano, Juan José; Parra, Genis; Laurie, Steve; Beltran, Sergi; EPICOLON Consortium; Castells, Antoni; Bujanda Fernández de Pierola, Luis ORCID; Cubiella, Joaquín; Balaguer, Francesc; Castellví-Bel, Sergi (MDPI, 2019-03-13)
      Colorectal cancer (CRC) shows aggregation in some families but no alterations in the known hereditary CRC genes. We aimed to identify new candidate genes which are potentially involved in germline predisposition to familial ...
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      Integrative development of a short screening questionnaire of highly processed food consumption (sQ-HPF) 

      Martínez Pérez, Celia; Daimiel, Lidia; Climent Mainar, Cristina; Martínez González, Miguel Ángel; Salas Salvadó, Jordi; Corella, Dolores; Schröder, Helmut; Martínez Hernández, J. Alfredo; Alonso Gómez, Ángel María ORCID; Wärnberg, Julia; Vioque, Jesús; Romaguera, Dora; López Miranda, José; Estruch, Ramón; Tinahones, Francisco J.; Lapetra, José; Serra Majem, Lluís; Bueno Cavanillas, Aurora; Tur, Josep A.; Martín Sánchez, Vicente; Pintó, Xabier; Delgado Rodríguez, Miguel; Matía Martín, Pilar; Vidal, Josep; Vázquez, Clotilde; Ros, Emilio; Basterra, Javier; Babio, Nancy; Guillem Saiz, Patricia; Zomeño Fajardo, María Dolores; Abete, Itziar; Vaquero Luna, Jessica; Barón López, Francisco Javier; González Palacios, Sandra; Konieczna, Jadwiga; García Ríos, Antonio; Bernal López, María Rosa; Santos Lozano, José Manuel; Bes Rastrollo, Maira; Khoury, Nadine; Saiz, Carmen; Pérez Vega, Karla Alejandra; Zulet, M. Ángeles; Tojal Sierra, Lucas; Vázquez Ruiz, Zenaida; Martínez, María Ángeles; Malcampo, Mireia; Ordovás, José María; San Cristóbal, Rodrigo (BMC, 2022)
      Background: Recent lifestyle changes include increased consumption of highly processed foods (HPF), which has been associated with an increased risk of non-communicable diseases (NCDs). However, nutritional information ...
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      Intravenous cyclophosphamide improves functional outcomes in interstitial lung disease related to idiopathic inflammatory myopathies 

      Moreno Torres, Víctor; Martín Iglesias, Daniel; Vivero, Florencia; González Echavarri, Cristina; García Moyano, Marta; Enghelmayer, Juan Ignacio; Malfante, Pablo; Gaser, Adrián; Ruiz Irastorza, Guillermo; EPIMAR cohort investigators (Elsevier, 2023-04)
      OBJECTIVE: To compare the efficacy, toxicity and glucocorticoid (GC)-sparing effects of intravenous cyclophosphamide (iv CYC) with other immunosuppressive regimes as the induction treatment for Idiopathic Inflammatory ...