Browsing Artículos, Comunicaciones, Libros by Author "Radulescu, Carola"
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Quantitative super-resolution imaging of pathological aggregates reveals distinct toxicity profiles in different synucleinopathies
Morten, Michael J.; Sirvio, Liina; Rupawala, Huzefa; Hayes, Emma Mee; Franco Budia, Aitor ; Radulescu, Carola; Barnes, Samuel J.; Muga Villate, Arturo ; Ye, Yu (National Academy of Sciences, 2022-10)Protein aggregation is a hallmark of major neurodegenerative disorders. Increasing data suggest that smaller aggregates cause higher toxic response than filamentous aggregates (fibrils). However, the size of small aggregates ...