Now showing items 1-20 of 156

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      A Comparative Study of Cell Culture Conditions during Conversion from Primed to Naive Human Pluripotent Stem Cells 

      Romayor Arredondo, Irene ORCID; Herrera, Lara ORCID; Burón, María ORCID; Martín Inaraja, Myriam; Prieto López, Laura; Etxaniz Díaz de Durana, Jone; Inglés Ferrándiz, Marta; Pineda Martí, José Ramón ORCID; Eguizabal Argaiz, Cristina ORCID (MDPI, 2022)
      The successful reprogramming of human somatic cells into induced pluripotent stem cells (hiPSCs) represented a turning point in the stem cell research field, owing to their ability to differentiate into any cell type with ...
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      A Customized Pigmentation SNP Array Identifies a Novel SNP Associated with Melanoma Predisposition in the SLC45A2 Gene 

      Ibarrola Villava, Maider; Fernandez, Lara P.; Alonso Alegre, Santos ORCID; Boyano López, María Dolores ORCID; Peña Chilet, María; Pita, Guillermo; Avilés, José A.; Mayor, Matias; Gómez Fernández, Cristina; Casado, Beatriz; Martín González, Manuel; Izagirre Arribalzaga, Neskuts ORCID; De la Rúa Vaca, Concepción ORCID; Asumendi Mallea, Aintzane ORCID; Pérez-Yarza Pérez-Irezabal, Gorka ORCID; Arroyo Berdugo, Yoana; Boldo, Enrique; Lozoya, Rafael; Torrijos Aguilar, Arantxa; Pitarch, Ana; Pitarch, Gerard; Sánchez Motilla, José M.; Valcuende Cavero, Francisca; Tomás Cabedo, Gloria; Pérez Pastor, Gemma; Díaz Pérez, José Luis; Gardeazabal García, Jesús; Martínez de Lizarduy, Iñigo; Sánchez Díez, Ana; Valdés, Carlos; Pizarro, Angel; Casado, Mariano; Carretero, Gregorio; Botella Estrada, Rafael; Nagore, Eduardo; Lázaro, Pablo; Lluch, Ana; Benítez, Javier; Martínez Cadenas, Conrado; Ribas, Gloria (Public Library of Science, 2011-04-29)
      As the incidence of Malignant Melanoma (MM) reflects an interaction between skin colour and UV exposure, variations in genes implicated in pigmentation and tanning response to UV may be associated with susceptibility to ...
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      A manual-based family intervention for families living with the consequences of traumatic injury to the brain or spinal cord: a study protocol of a randomized controlled trial 

      Langer Soendergaard, Pernille; Moth Wolffbrandt, Mia; Biering Sørensen, Fin; Nordin, Malin; Schow, Trine; Arango Lasprilla, Juan Carlos; Norup, Anne (BMC, 2019-11-27)
      Background Acquiring a traumatic injury constitutes a severe life change for the survivor, but also for the surrounding family. The paradigm of helping the family has primarily been on psychosocial interventions targeting ...
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      A novel brain partition highlights the modular skeleton shared by structure and function 

      Diez Palacio, Ibai; Bonifazi, Paolo; Escudero, Iñaki; Mateos, Beatriz; Muñoz, Miguel A.; Stramaglia, Sebastiano; Cortés Díaz, Jesús María (Nature Publishing Group, 2015-06-03)
      Elucidating the intricate relationship between brain structure and function, both in healthy and pathological conditions, is a key challenge for modern neuroscience. Recent progress in neuroimaging has helped advance our ...
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      A Pilot Study of a Panel of Ocular Inflammation Biomarkers in Patients with Primary Sjögren’s Syndrome 

      Boto de los Bueis, Ana; de la Fuente, Miguel; Montejano Milner, Rafael; del Hierro Zarzuelo, Almudena; Vecino Cordero, Elena ORCID; Acera Osa, Arantxa (MDPI, 2023-04-01)
      Ocular diseases have a strong impact on individuals, the effects of which extend from milder visual impairment to blindness. Due to this and to their prevalence, these conditions constitute important health, social and ...
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      A Study of the Printability of Alginate-Based Bioinks by 3D Bioprinting for Articular Cartilage Tissue Engineering 

      Gorroñogoitia, Izar; Urtaza, Uzuri; Zubiarrain Laserna, Ana; Alonso Varona, Ana Isabel; Zaldua Huici, Ane Miren (MDPI, 2022-01-17)
      Three-dimensional bioprinting combined with natural hydrogels is a promising technology for the treatment of several pathologies and different tissue regeneration. One of the most studied tissues is cartilage, a complex ...
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      A Universal Antigen-Ranking Method to Design Personalized Vaccines Targeting Neoantigens against Melanoma 

      Malaina Celada, Iker ORCID; Martínez Fernández, Luis ORCID; Montoya, Juan Manuel; Alonso Alegre, Santos ORCID; Boyano López, María Dolores ORCID; Asumendi Mallea, Aintzane ORCID; Izu Belloso, Rosa María; Sánchez Díez, Ana; Cancho Galán, Goikoane; Martínez de la Fuente Martínez, Ildefonso Abel (MDPI, 2023-01-05)
      Background: The main purpose of this article is to introduce a universal mathematics-aided vaccine design method against malignant melanoma based on neoantigens. The universal method can be adapted to the mutanome of each ...
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      Adenylate Cyclase Toxin promotes bacterial internalisation into non phagocytic cells 

      Martín Plágaro, César Augusto ORCID; Etxaniz Iriondo, Asier ORCID; Belloso Uribe, Kepa; Etxebarria Gallego, Aitor; González Bullón, David ORCID; Arluzea de Jauregizar, Jon Andoni ORCID; Goñi Urcelay, Félix María ORCID; Arechaga Martínez, Juan Miguel ORCID; Ostolaza Echabe, Elena Amaya ORCID (Nature Publishing Group, 2015-09-08)
      Bordetella pertussis causes whooping cough, a respiratory infectious disease that is the fifth largest cause of vaccine-preventable death in infants. Though historically considered an extracellular pathogen, this bacterium ...
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      Advances and Perspectives in Dental Pulp Stem Cell Based Neuroregeneration Therapies 

      Luzuriaga González, Jon ORCID; Polo Arroyabe, Yurena; Pastor Alonso, Oier; Pardo Rodríguez, Beatriz; Larrañaga Espartero, Aitor ORCID; Unda Rodríguez, Fernando José ORCID; Sarasua Oiz, José Ramón ORCID; Pineda Martí, José Ramón ORCID; Ibarretxe Bilbao, Gaskon ORCID (MDPI, 2021-03-29)
      Human dental pulp stem cells (hDPSCs) are some of the most promising stem cell types for regenerative therapies given their ability to grow in the absence of serum and their realistic possibility to be used in autologous ...
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      Altered expression of fibroblast activation protein-α (FAP) in colorectal adenoma-carcinoma sequence and in lymph node and liver metastases 

      Solano Iturri, Jon Danel; Beitia Loinaz, Maider; Errarte Yarza, Peio; Calvete Candenas, Julio; Etxezarraga Zuluaga, María Carmen; Loizate Totoricagüena, Alberto; Echevarría Orella, Enrique ORCID; Badiola Echaburu, Iker ORCID; Larrinaga Embeita, Gorka ORCID (Impact Journals, 2020-06-15)
      Colorectal cancer (CRC) is a major health problem in elderly people because of its high incidence and high mortality rate. Despite early screening programs, more than half of CRC patients are diagnosed at advanced stages. ...
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      An E2F7-Dependent Transcriptional Program Modulates DNA Damage Repair And Genomic Stability 

      Michelena Sánchez, Jone ORCID; Apraiz García, Aintzane ORCID; Vallejo Rodríguez, Jon ORCID; García Santisteban, Iraia ORCID; Fullaondo Elordui-Zapaterieche, Asier ORCID; Alvarez Fernández, Mónica; Marcos, Marcos; Zubiaga Elordieta, Ana María ORCID (Oxford University Press, 2018-05-18)
      The cellular response to DNA damage is essential for maintaining the integrity of the genome. Recent evidence has identified E2F7 as a key player in DNA damage-dependent transcriptional regulation of cell-cycle genes. ...
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      An Integrative Omics Approach Reveals Involvement of BRCA1 in Hepatic Metastatic Progression of Colorectal Cancer 

      Gerovska, Daniela; Larrinaga Embeita, Gorka ORCID; Solano Iturri, Jon Danel; Márquez Clavijo, Joana ORCID; García Gallastegui, Patricia ORCID; Khatib, Abdel Majid; Poschmann, Gereon; Stühler, Kai; Armesto, María; Lawrie, Charles; Badiola Echaburu, Iker ORCID; Araúzo Bravo, Marcos J. (MDPI, 2020-08-22)
      (1) Background & Aims: The roles of different cells in the tumor microenvironment (TME) are critical to the metastatic process. The phenotypic transformation of the liver cells is one of the most important stages of the ...
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      Antioxidant-Based Therapy Reduces Early-Stage Intestinal Ischemia-Reperfusion Injury in Rats 

      Gutiérrez Sánchez, Gaizka; García-Alonso Montoya, Ignacio ORCID; Gutiérrez Sáenz de Santa María, Jorge; Alonso Varona, Ana Isabel; Herrero de la Parte, Borja (MDPI, 2021-05-27)
      Intestinal ischemia-reperfusion injury (i-IRI) is a rare disorder with a high mortality rate, resulting from the loss of blood flow to an intestinal segment. Most of the damage is triggered by the restoration of flow and ...
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      Aplicación de tecnologías disruptivas en telemedicina para la cobertura universal de servicios de salud 

      Galván, P.; Rivas, Ronald; Ortellado, José; Portillo, Juan; Mazzoleni, Julio; Hilario Rodríguez, Enrique ORCID (Instituto Nacional De Salud - MSP y BS, 2020-06)
      [ES] La aplicación de tecnologías disruptivas en telemedicina facilita la accesibilidad a tecnologías diagnósticas de poblaciones remotas sin acceso a especialistas y mejora la cobertura universal de servicios de salud. ...
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      Are environmental risk factors for current wheeze in the International Study of Asthma and Allergies in Childhood (ISAAC) phase three due to reverse causation? 

      ISAAC Phase Three Study Group; González Díaz, Carlos; Pérez-Yarza Pérez-Irezabal, Gorka ORCID (Wiley, 2019-04)
      Background: Phase Three of the International Study of Asthma and Allergies in Childhood (ISAAC) measured the global prevalence of symptoms of asthma in children. We undertook comprehensive analyses addressing risk factors ...
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      Association among University Students’ Motivation, Resilience, Perceived Competence, and Classroom Climate from the Perspective of Self-Determination Theory 

      Sánchez de Miguel, Manuel Norberto ORCID; Orkaizagirre Gomara, Aintzane ORCID; Izagirre Otaegi, Andrea; Badiola Echaburu, Iker ORCID; Ortiz de Elguea Díaz, Francisco Javier ORCID; Gómez Gastiasoro, Ainara; Ferriz Valero, Alberto; Goudas, Marios (MDPI, 2023-01-30)
      Self-determination theory (SDT) suggests that motivation can interact with resilience and perceived competence. The climate-related characteristics of the classroom can influence student motivation. This study aimed to ...
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      Association of TYR SNP rs1042602 with Melanoma Risk and Prognosis 

      Sevilla Mambrilla, Arrate ORCID; Sánchez Díez, Ana; Cobo, Sofía; Izagirre Arribalzaga, Neskuts ORCID; Martínez Cadenas, Conrado; Martí Laborda, Rosa María; Puértolas, Teresa; de Unamuno, Blanca; Bañuls, José; Izu Belloso, Rosa María; Gardeazabal García, Jesús; Asumendi Mallea, Aintzane ORCID; Boyano López, María Dolores ORCID; Alonso Alegre, Santos ORCID (MDPI, 2022-12-01)
      Cutaneous melanoma is the most aggressive of skin tumors. In order to discover new biomarkers that could help us improve prognostic prediction in melanoma patients, we have searched for germline DNA variants associated ...
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      Associative Conditioning Is a Robust Systemic Behavior in Unicellular Organisms: An Interspecies Comparison 

      Carrasco-Pujante, Jose; Bringas Roldán, Carlos; Malaina Celada, Iker ORCID; Fedetz, Maria; Martínez Fernández, Luis ORCID; Pérez-Yarza Pérez-Irezabal, Gorka ORCID; Boyano López, María Dolores ORCID; Berdieva, Mariia; Goodkov, Andrew; López, José I.; Knafo Farhi, Dina Shira; Martínez de la Fuente Martínez, Ildefonso Abel (Frontiers Media, 2021-07-19)
      The capacity to learn new efficient systemic behavior is a fundamental issue of contemporary biology. We have recently observed, in a preliminary analysis, the emergence of conditioned behavior in some individual amoebae ...
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      BDNF and NT3 Reprogram Human Ectomesenchymal Dental Pulp Stem Cells to Neurogenic and Gliogenic Neural Crest Progenitors Cultured in Serum-Free Medium 

      Luzuriaga González, Jon ORCID; Pineda Martí, José Ramón ORCID; Irastorza Epelde, Igor ORCID; Uribe Etxebarria, Veronica; García Gallastegui, Patricia ORCID; Encinas Pérez, Juan Manuel; Chamero, Pablo; Unda Rodríguez, Fernando José ORCID; Ibarretxe Bilbao, Gaskon ORCID (Cell Physiol Biochem Press, 2019-05-11)
      Background/aims: Human Dental Pulp Stem Cells (hDPSCs) are one of the most promising types of cells to regenerate nerve tissues. Standard DMEM+10% fetal bovine serum (FBS) culture medium allows a fast expansion of hDPSC ...
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      Bioactive Materials for Next-Generation Dentistry 

      Ibarretxe Bilbao, Gaskon ORCID (MDPI, 2022-12-08)
      Teeth were some of the first organs whose function was effectively restored by inert refilling materials that have become widely known to the general public; amalgams, polymeric resin composites, and gutta-percha are some ...