Examinar Artículos, Comunicaciones, Libros por departamento (eus.) "https://www.liebertpub.com/doi/10.1089/zeb.2016.1313"

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Pharmacokinetic Modeling of Paracetamol Uptake and Clearance in Zebrafish Larvae: Expanding the Allometric Scale in Vertebrates with Five Orders of Magnitude

Kantae, Vasudev; Krekels, Elke H.J.; Ordas, Anita; González Mendia, Oscar ; van Wijk, Rob C.; Harms, Amy C.; Racz, Peter I.; van de Graaf, Piet H.; Spaink, Herman P.; Hankemeier, Thomas (Mary Ann Liebert, 2016-12-01)

Zebrafish larvae (Danio rerio) are increasingly used to translate findings regarding drug efficacy and safety from in vitro-based assays to vertebrate species, including humans. However, the limited understanding of drug ...