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Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses
(Elsevier, 2023-04)
Subunit vaccines typically require co-administration with an adjuvant to elicit protective immunity, adding development hurdles that can impede rapid pandemic responses. To circumvent the need for adjuvant in a severe acute ...
Influence of methyl donor nutrients as epigenetic regulators in colorectal cancer: A systematic review of observational studies
(Baishideng, 2023)
BACKGROUNDDietary methyl donors might influence DNA methylation during carcinogenesis of colorectal cancer (CRC). However, whether the influence of methyl donor intake is modified by polymorphisms in such epigenetic ...
Zeolites as Ingredients of Medicinal Products
(MDPI, 2023-04-28)
Development of new medicinal products for particular therapeutic treatment or for better manipulations with better quality and less side effects are possible as a result of advanced inorganic and organic materials application, ...
High resolution and fidelity 3D printing of Laponite and alginate ink hydrogels for tunable biomedical applications
(Elsevier, 2023-06)
The formulation of hydrogels that meet the necessary flow characteristics for their extrusion-based 3D printing while providing good printability, resolution, accuracy and stability, requires long development processes. ...
Tumour-derived extracellular vesicle based vaccines for melanoma treatment
(Springer, 2023-05)
The interest of extracellular vesicles (EVs) in cancer immunotherapy is increasing every day. EVs are lipid bilayer vesicles released by most cells, which contain the molecular signature of their parent cell. Melanoma-derived ...
Vegetable By-Products as Alternative and Sustainable Raw Materials for Ruminant Feeding: Nutritive Evaluation and Their Inclusion in a Novel Ration for Calf Fattening
(MDPI, 2023-04-18)
This research aimed to evaluate the nutritional composition, in vitro digestibility, and gas production kinetics of 15 vegetable by-products generated by the agri-food industry compared with corn silage as a reference raw ...
Prevalence and Predictors of Food Insecurity among Students of a Spanish University during the COVID-19 Pandemic: FINESCOP Project at the UPV/EHU
(MDPI, 2023-04-11)
Research related to food insecurity (FI) among European university student populations is currently limited, especially the studies carried out during the COVID-19 pandemic. The present study aimed to assess the prevalence ...
Pharmacokinetic/Pharmacodynamic Analysis of Oral Calcium Fosfomycin: Are Urine Levels Sufficient to Ensure Efficacy for Urinary Tract Infections?
(MDPI, 2023-04-07)
Urinary tract infections (UTIs) are extremely common and a major driver for the use of antimicrobials. Calcium fosfomycin is an old antibiotic indicated for the treatment of UTIs; however, data about its urine pharmacokinetic ...
Anti-Steatotic Effects of Chlorella vulgaris, Nannochloropsis gaditana and Gracilaria vermiculophylla Algae Extracts in AML-12 Hepatocytes
(MDPI, 2023-04-19)
Non-alcoholic fatty liver disease (NAFLD) is considered the most common chronic liver alteration whose prevalence is increasing in Western countries. Microalgae and macroalgae have attracted great interest due to the high ...
Characterization and assessment of new fibrillar collagen inks and bioinks for 3D printing and bioprinting
(AccScience Publishing, 2023-03-16)
Collagen is a cornerstone protein for tissue engineering and 3D bioprinting due to its outstanding biocompatibility, low immunogenicity, and natural abundance in human tissues. Nonetheless, it still poses some important ...