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Estimation of preterm labor immediacy by nonlinear methods
(Public Library Science, 2017-06-01)
Preterm delivery affects about one tenth of human births and is associated with an increased perinatal morbimortality as well as with remarkable costs. Even if there are a number of predictors and markers of preterm delivery, ...
Involvement of ANXA5 and ILKAP in Susceptibility to Malignant Melanoma
(Public Library Science, 2014-04-17)
Single nucleotide-polymorphisms (SNPs) are a source of diversity among human population, which may be responsible for the different individual susceptibility to diseases and/or response to drugs, among other phenotypic ...
GeromiRs Are Downregulated in the Tumor Microenvironment during Colon Cancer Colonization of the Liver in a Murine Metastasis Model
(MDPI, 2021-05-01)
Cancer is a phenomenon broadly related to ageing in various ways such as cell cycle deregulation, metabolic defects or telomerases dysfunction as principal processes. Although the tumor cell is the main actor in cancer ...
Foveal remodeling of retinal microvasculature in Parkinson’s disease
(Frontiers Media, 2021-07-12)
[EN] Background: Retinal microvascular alterations have been previously described in
Parkinson’s disease (PD) patients using optical coherence tomography angiography
(OCT-A). However, an extensive description of retinal ...
H2O2-preconditioned human adipose-derived stem cells (HC016) increase theirresistance to oxidative stress byoverexpressing Nrf2 and bioenergetic adaptation
(Biomed Central, 2020-08-03)
BackgroundMesenchymal stem cells, including those derived from human adipose tissue (hASCs), are currently being widely investigated for cell therapy. However, when transplanted at the site of injury, the survival and ...
Hydrogen Peroxide-Preconditioned Human Adipose-Derived Stem Cells Enhance the Recovery of Oligodendrocyte-Like Cells after Oxidative Stress-Induced Damage
(MDPI, 2020-12-14)
Oxidative stress associated with neuroinflammation is a key process involved in the pathophysiology of neurodegenerative diseases, and therefore, has been proposed as a crucial target for new therapies. Recently, the ...
Development and evaluation of different electroactive poly(vinylidene fluoride) architectures for endothelial cell culture
(Frontiers Media, 2022)
Tissue engineering (TE) aims to develop structures that improve or even replace the biological functions of tissues and organs. Mechanical properties, physical-chemical characteristics, biocompatibility, and biological ...
shinyCurves, a shiny web application to analyse multisource qPCR amplification data: a COVID‑19 case study
(BMC, 2021-10-03)
[EN]Background Quantitative, reverse transcription PCR (qRT-PCR) is currently the gold-standard for SARS-CoV-2 detection and it is also used for detection of other virus. Manual data analysis of a small number of qRT-PCR ...
Upregulated phospholipase D2 expression and activity is related to the metastatic properties of melanoma
(Spandidos, 2022-05)
[EN] The incidence rates of melanoma have increased steadily in recent decades and nearly 25% of the patients diagnosed with early-stage melanoma will eventually develop metastasis, for which there is currently no fully ...
Are environmental risk factors for current wheeze in the International Study of Asthma and Allergies in Childhood (ISAAC) phase three due to reverse causation?
(Wiley, 2019-04)
Background: Phase Three of the International Study of Asthma and Allergies in Childhood (ISAAC) measured the global prevalence of symptoms of asthma in children. We undertook comprehensive analyses addressing risk factors ...