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Soluble PD-L1 Is an Independent Prognostic Factor in Clear Cell Renal Cell Carcinoma
(MDPI, 2021-02-07)
(1). Background: Immunohistochemical (IHC) evaluation of programmed death-1 (PD-1) and its ligand (PD-L1) is being used to evaluate advanced malignancies with potential response to immune checkpoint inhibitors. We evaluated ...
Clinical Implications of (Pro)renin Receptor (PRR) Expression in Renal Tumours
(MDPI, 2021-02-10)
(1) Background: Renal cancer is one of the most frequent malignancies in Western countries, with an unpredictable clinical outcome, partly due to its high heterogeneity and the scarcity of reliable biomarkers of tumour ...
Altered Tissue and Plasma Levels of Fibroblast Activation Protein-α (FAP) in Renal Tumours
(MDPI, 2020-10-16)
(1) Background: Renal cell carcinoma (RCC) is a heterogeneous and complex disease with only partial response to therapy, high incidence of metastasis and recurrences, and scarce reliable biomarkers indicative of progression ...
Obesity Parameters, Physical Activity, And Physical Fitness are Correlated With Serum Dipeptidyl Peptidase IV Activity In A Healthy Population
(Elsevier, 2018-05)
Objective: To determine whether obesity, physical fitness, and physical activity parameters are associated with the enzymatic activity of serum dipeptidyl peptidase IV (sDPPIV) in a sample of healthy women and men.
Design ...
Sex differences in the aging pattern of renin–angiotensin system serum peptidases
(Biomed Central, 2017-02-03)
Background: Serum peptidases, such as angiotensin-converting enzyme (ACE), angiotensin-converting enzyme-2 (ACE2), neutral endopeptidase (NEP), aminopeptidase N (APN), and aminopeptidase A (APA), are important elements of ...
Injury risk is greater in physically mature versus biologically younger male soccer players from academies in different countries
(Elsevier, 2022-05)
Objectives: To investigate if maturity status was associated with injury risk in male academy soccer players. Design: Prospective cohort surveillance study. Setting: Professional soccer academies. Participants: 501 players ...
Metabolism of renin-angiotensin and enkephalin in human follicular fluid: An experimental study.
(Shahid Sadoughi University of Medical Sciences, 2022-10)
Background: The relationship between the biochemical characteristics of follicular fluid (FF), oocyte quality and embryonic development has not yet been elucidated. We compared samples of FF with a normal metabolic profile ...
Ramadan Observance Exacerbated the Negative Effects of COVID-19 Lockdown on Sleep and Training Behaviors: A International Survey on 1,681 Muslim Athletes
(Frontiers Media, 2022-06)
ObjectiveDisrupted sleep and training behaviors in athletes have been reported during the COVID-19 pandemic. We aimed at investigating the combined effects of Ramadan observance and COVID-19 related lockdown in Muslim ...
Lockdown Duration and Training Intensity Affect Sleep Behavior in an International Sample of 1,454 Elite Athletes
(Frontiers Media, 2022-06)
Objective: To investigate the effect of 1) lockdown duration and 2) training intensity on sleep quality and insomnia symptoms in elite athletes.Methods: 1,454 elite athletes (24.1 +/- 6.7 years; 42% female; 41% individual ...
Do Thirty-Second Post-activation Potentiation Exercises Improve the 50-m Freestyle Sprint Performance in Adolescent Swimmers?
(Frontiers Media, 2018-10-22)
Objectives: The purpose of the study was to investigate performance, biomechanical, physiological, and psychophysiological effects of a simple and easily organized post-activation potentiation (PAP) re-warm-up performed ...